Structural Classification of Proteins
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Family: RecA protein-like (ATPase-domain)

core: mixed beta-sheet of 8 strands, order 32451678; strand 7 is antiparallel to the rest

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: P-loop containing nucleoside triphosphate hydrolases [52539]
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily: P-loop containing nucleoside triphosphate hydrolases [52540]
    division into families based on beta-sheet topologies
    link to SUPERFAMILY database - Superfamily
  5. Family: RecA protein-like (ATPase-domain) [52670]
    core: mixed beta-sheet of 8 strands, order 32451678; strand 7 is antiparallel to the rest

Protein Domains:

  1. RecA protein, ATPase-domain [52671]
    C-terminal domain is alpha+beta
    1. Escherichia coli [TaxId: 562] [52672] (7) picpic
      SQ P0A7G6 P03017
    2. Mycobacterium tuberculosis [TaxId: 1773] [52673] (6) picpic
    3. Mycobacterium smegmatis [TaxId: 1772] [89675] (4) picpic
    4. Deinococcus radiodurans [TaxId: 1299] [117540] (1) picpic
      SQ P42443 15-341
  2. Gene 4 protein (g4p, DNA primase), helicase domain [52674]
    1. Bacteriophage T7 [TaxId: 10760] [52675] (7) picpic
  3. Hexameric replicative helicase repA [52676]
    1. Escherichia coli [TaxId: 562] [52677] (3) picpic
  4. Bacterial conjugative coupling protein TrwB [69492]
    1. Escherichia coli [TaxId: 562] [69493] (5) picpic
  5. Hexameric traffic ATPase, HP0525 [52719]
    type II/IV secretion system protein; includes N-terminal alpha+beta domain of a profilin-like topology
    1. Helicobacter pylori [TaxId: 210] [52720] (6) picpic
  6. Extracellular secretion NTPase EpsE [102375]
    type II/IV secretion system protein; overall structure is similar to HP0525
    1. Vibrio cholerae [TaxId: 666] [102376] (2) picpic
  7. DNA repair protein Rad51, catalytic domain [82412]
    1. Human (Homo sapiens) [TaxId: 9606] [82413] (1) picpic
    2. Archaeon Pyrococcus furiosus [TaxId: 2261] [102377] (1) picpic
    3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110554] (1) picpic
      SQ P25454 81-395
    4. Archaeon Methanococcus voltae [TaxId: 2188] [110555] (8) picpic
      SQ O73948
  8. Central domain of alpha subunit of F1 ATP synthase [88774]
    1. Cow (Bos taurus) [TaxId: 9913] [88775] (18) picpic
      SQ P19483
    2. Rat (Rattus norvegicus) [TaxId: 10116] [88776] (2) picpic
    3. Bacillus sp., strain ps3 [TaxId: 1409] [88777] (1) picpic
    4. Spinach (Spinacia oleracea), chloroplast [TaxId: 3562] [88778] (2) picpic
  9. Central domain of beta subunit of F1 ATP synthase [88779]
    1. Cow (Bos taurus) [TaxId: 9913] [88780] (12) picpic
      SQ P00829
    2. Rat (Rattus norvegicus) [TaxId: 10116] [88781] (8) picpic
    3. Bacillus sp., strain ps3 [TaxId: 1409] [88782] (1) picpic
    4. Spinach (Spinacia oleracea), chloroplast [TaxId: 3562] [88783] (2) picpic
  10. Transcription termination factor Rho, ATPase domain [89676]
    1. Escherichia coli [TaxId: 562] [89677] (10) picpic
      SQ P03002
  11. Adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase CobU [52682]
    lacks the last strand 8
    1. Salmonella typhimurium [TaxId: 90371] [52683] (2) picpic
  12. ATP:corrinoid adenosyltransferase CobA [52684]
    lacks the two last strands
    1. Salmonella typhimurium [TaxId: 90371] [52685] (3) picpic
  13. Meiotic recombination protein DMC1/LIM15 homolog [110556]
    1. Human (Homo sapiens) [TaxId: 9606] [110557] (1) picpic
      SQ Q14565
  14. Circadian clock protein KaiC [110558]
    duplication: contains two copies of this domain
    1. Synechococcus sp. strain PCC 7942 (Anacystis nidulans R2) [TaxId: 1140] [110559] (25) picpic
      SQ Q79PF4 14-497
  15. NTPase P4 [117541]
    contains extra N-terminal subdomain (~100 residues): [contains pseudo beta-barrel]
    1. Bacteriophage phi-12 [TaxId: 161736] [117542] (8) picpic
      SQ Q94M05
  16. Hypothetical kinase-like protein Aq_1292 [142301]
    member of Pfam 03266 (DUF265)
    1. Aquifex aeolicus [TaxId: 63363] [142302] (1) picpic
      SQ O67322 1-178
  17. Cancer-related NTPase, C1orf57 [159566]
    member of Pfam 03266; DUF265
    1. Human (Homo sapiens) [TaxId: 9606] [159567] (1) picpic
      SQ Q5TDE9 2-190
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk