Family: Nitrogenase iron protein-like

core: parallel beta-sheet of 7 strands; order 3241567

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: P-loop containing nucleoside triphosphate hydrolases [52539]
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
4. Superfamily: P-loop containing nucleoside triphosphate hydrolases [52540]
   division into families based on beta-sheet topologies
   uperfamily
5. Family: Nitrogenase iron protein-like [52652]
   core: parallel beta-sheet of 7 strands; order 3241567

Protein Domains:

1. Dethiobiotin synthetase [52653]
   1. Escherichia coli [TaxId: 562] [52654] (13)
2. Adenylosuccinate synthetase, PurA [52655]
   common fold is interrupted by an all-alpha subdomain, residues 100-200
   1. Escherichia coli [TaxId: 562] [52656] (24)
   2. Mouse-ear cress (Arabidopsis thaliana) [TaxId: 3702] [52657] (1)
   3. Bread wheat (Triticum aestivum) [TaxId: 4565] [52658] (1)
   4. Mouse (Mus musculus) [TaxId: 10090] [69491] (9)
   5. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [102372] (1)
3. Formyltetrahydrofolate synthetase [52659]
   modified P-loop; there are many insertions in the common fold
   1. Moorella thermoacetica [TaxId: 1525] [52660] (3)
4. Nitrogenase iron protein [52661]
   1. Azotobacter vinelandii [TaxId: 354] [52662] (19)
   2. Clostridium pasteurianum [TaxId: 1501] [52663] (1)
5. Cell division regulator MinD [64019]
   1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [64020] (1)
   2. Archaeon Pyrococcus furiosus [TaxId: 2261] [64021] (2)
   3. Archaeon Pyrococcus horikoshii [TaxId: 53953] [64022] (1)
6. GTPase domain of the signal sequence recognition protein Ffh [52664]
   1. Thermus aquaticus [TaxId: 271] [52665] (25)
   2. Archaeon Acidianus ambivalens [TaxId: 2283] [64023] (2)
   3. Archaeon Sulfolobus solfataricus [TaxId: 2287] [102373] (2)
7. GTPase domain of the signal recognition particle receptor FtsY [52666]
   1. Escherichia coli [TaxId: 562] [52667] (2)
   2. Thermus aquaticus [TaxId: 271] [102374] (8)
   3. Thermotoga maritima [TaxId: 2336] [110550] (1)
      SQ Q9WZ40
8. Arsenite-translocating ATPase ArsA [52668]
   Duplication: consists of two domains of this fold arranged as the NIP subunits in the dimer
   1. Escherichia coli [TaxId: 562] [52669] (4)
9. Hypothetical protein YjiA, N-terminal domain [89671]
   homologue of the cobalamin biosynthesis protein CobW
   1. Escherichia coli [TaxId: 562] [89672] (1)
10. Molybdopterin-guanine dinucleotide biosynthesis protein MobB [89673]
    forms segment-swapped dimer
    1. Escherichia coli [TaxId: 562] [89674] (2)
    2. Bacillus stearothermophilus [TaxId: 1422] [117539] (1)
       SQ Q5L1X2 # 91% sequence identity
11. CTP synthase PyrG, N-terminal domain [110551]
    1. Escherichia coli [TaxId: 562] [110552] (1)
       SQ P08398
    2. Thermus thermophilus [TaxId: 274] [110553] (3)
       SQ Q5SIA8
    3. Human (Homo sapiens) [TaxId: 9606] [159561] (2)
       SQ Q5VW67 1-273
12. ATP(GTP)-binding protein PAB0955 [142297]
    PYRAB14380; belongs to Pfam 03029
    1. Pyrococcus abyssi [TaxId: 29292] [142298] (9)
       SQ Q9UYR9 30-273
13. Hypothetical protein TM0796 [142299]
    member of Pfam 07755; DUF1611; contains extra N-terminal alpha/beta fold of Rossmann-fold topology, parallel beta-sheet, strand order 312456
    1. Thermotoga maritima [TaxId: 2336] [142300] (2)
       SQ Q9WZQ3 1-338
14. LAO/AO transport system kinase ArgK [159562]
    member of Pfam 03308; contains extra N-terminal 3-helical bundle and extra C-terminal helical dimerisation domain
    1. Escherichia coli [TaxId: 562] [159563] (1)
       SQ P27254 1-327
15. Metallochaperone MeaB [159564]
    ArgK-like (sub)family; Pfam 03308
    1. Methylobacterium extorquens [TaxId: 408] [159565] (4)
       SQ Q8RPA0 5-327

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk