Structural Classification of Proteins
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Family: Nucleotide and nucleoside kinases

parallel beta-sheet of 5 strands, order 23145

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: P-loop containing nucleoside triphosphate hydrolases [52539]
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. Superfamily: P-loop containing nucleoside triphosphate hydrolases [52540]
    division into families based on beta-sheet topologies
    link to SUPERFAMILY database - Superfamily
  5. Family: Nucleotide and nucleoside kinases [52541]
    parallel beta-sheet of 5 strands, order 23145

Protein Domains:

  1. Guanylate kinase [52542]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [52543] (3) picpic
    2. Mouse (Mus musculus) [TaxId: 10090] [82393] (1) picpic
    3. Escherichia coli [TaxId: 562] [102338] (18) picpic
    4. Mycobacterium tuberculosis [TaxId: 1773] [102339] (5) picpic
      Rv1389
  2. Guanylate kinase-like domain of Cask [69474]
    1. Human (Homo sapiens) [TaxId: 9606] [69475] (1) picpic
  3. Guanylate kinase-like domain of Psd-95 [69476]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [69477] (3) picpic
  4. Uridylate kinase [52544]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [52545] (2) picpic
  5. Deoxynucleoside monophosphate kinase [52546]
    contains insert 4-helical bundle subdomain, residues 35-145
    1. Bacteriophage T4 [TaxId: 10665] [52547] (2) picpic
  6. Deoxyribonucleoside kinase [69478]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [69479] (37) picpic
  7. Deoxycytidine kinase [89657]
    1. Human (Homo sapiens) [TaxId: 9606] [89658] (13) picpic
  8. Deoxyguanosine kinase [69480]
    1. Human (Homo sapiens) [TaxId: 9606] [69481] (8) picpic
  9. CMP kinase [52548]
    1. Escherichia coli [TaxId: 562] [52549] (6) picpic
    2. Streptococcus pneumoniae [TaxId: 1313] [110525] (1) picpic
      SQ Q97PK6
  10. UMP/CMP kinase [52550]
    1. Dictyostelium discoideum [TaxId: 44689] [52551] (6) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [110526] (1) picpic
      SQ P30085
  11. Thymidine kinase [52552]
    contains insert all-alpha subdomain, res. 251-322
    1. Herpes simplex virus type 1, different strains [TaxId: 10298] [52553] (22) picpic
      SQ P03176 46-375
    2. Equine herpesvirus type 4 [TaxId: 10331] [102340] (4) picpic
    3. Varicella-zoster virus [TaxId: 10335] [89659] (1) picpic
  12. Adenylate kinase [52554]
    1. Pig (Sus scrofa) [TaxId: 9823] [52555] (1) picpic
    2. Archaeon Sulfolobus acidocaldarius [TaxId: 2285] [52556] (1) picpic
    3. Archaeon Methanococcus voltae [TaxId: 2188] [89660] (1) picpic
    4. Archaeon Methanococcus thermolithotrophicus [TaxId: 2186] [89661] (1) picpic
    5. Cow (Bos taurus), mitochondrial izozyme-3 [TaxId: 9913] [52557] (1) picpic
      contains a rudiment "zinc-finger" subdomain, residue 125-161
    6. Cow (Bos taurus), mitochondrial izozyme-2 [TaxId: 9913] [52558] (2) picpic
      contains a rudiment "zinc-finger" subdomain, residue 147-176
    7. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [52559] (4) picpic
      contains a rudiment "zinc-finger" subdomain, residue 131-168
    8. Escherichia coli [TaxId: 562] [52560] (6) picpic
      contains a rudiment "zinc-finger" subdomain, residue 122-156
    9. Maize (Zea mays) [TaxId: 4577] [52561] (1) picpic
    10. Bacillus stearothermophilus [TaxId: 1422] [52562] (3) picpic
      contains a zinc-finger subdomain, residues 126-160
    11. Bacillus subtilis [TaxId: 1423] [102341] (1) picpic
      contains a zinc-finger subdomain, residues 126-160
    12. Bacillus globisporus [TaxId: 1459] [102342] (1) picpic
      contains a zinc-finger subdomain, residues 126-160
    13. Mycobacterium tuberculosis [TaxId: 1773] [102343] (2) picpic
      contains no zinc finger-like insertion
    14. Human (Homo sapiens), isoenzyme 6 [TaxId: 9606] [117527] (1) picpic
      SQ Q9Y3D8
  13. Thymidylate kinase [52563]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [52564] (3) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [64010] (20) picpic
    3. Escherichia coli [TaxId: 562] [52565] (2) picpic
    4. Mycobacterium tuberculosis [TaxId: 1773] [69482] (13) picpic
  14. Dephospho-CoA kinase [75187]
    1. Haemophilus influenzae [TaxId: 727] [75188] (1) picpic
    2. Escherichia coli [TaxId: 562] [82394] (5) picpic
    3. Thermus thermophilus [TaxId: 274] [102344] (1) picpic
      TT1252
  15. Transcriptional regulator NadR, ribosylnicotinamide kinase domain [75189]
    1. Haemophilus influenzae [TaxId: 727] [75190] (1) picpic
  16. Polynucleotide kinase, kinase domain [75191]
    1. Bacteriophage T4 [TaxId: 10665] [75192] (17) picpic
  17. Guanylate kinase-like domain of the L-type calcium channel [110527]
    1. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [110528] (4) picpic
      SQ P54288 234-451
    2. Rat (Rattus norvegicus) [TaxId: 10116] [110529] (3) picpic
      SQ P54287 38-362
  18. Probable kinase LmjF30.1890 [117528]
    1. Leishmania major [TaxId: 5664] [117529] (1) picpic
      SQ Q4Q7A6
  19. Hypothetical protein YorR [142211]
    1. Bacillus subtilis [TaxId: 1423] [142212] (2) picpic
      SQ O31896 2-165
  20. 5' polynucleotide kinase-3' phosphatase, C-terminal domain [142213]
    1. Mouse (Mus musculus) [TaxId: 10090] [142214] (2) picpic
      SQ Q9JLV6 351-522
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk