Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

family members also share a common alpha+beta fold in C-terminal domain

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: NAD(P)-binding Rossmann-fold domains [51734]
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar
4. Superfamily: NAD(P)-binding Rossmann-fold domains [51735]
   uperfamily
5. Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800]
   family members also share a common alpha+beta fold in C-terminal domain

Protein Domains:

1. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801]
   1. Escherichia coli [TaxId: 562] [51802] (13)
      SQ P06977
   2. Bacillus stearothermophilus, nca 1503 [TaxId: 1422] [51803] (14)
   3. Achromobacter xylosoxidans [TaxId: 85698] [89526] (1)
      formerly Alcaligenes xylosoxidans
   4. Thermus aquaticus [TaxId: 271] [51804] (13)
   5. Thermus thermophilus [TaxId: 274] [102157] (1)
   6. Thermotoga maritima [TaxId: 2336] [51805] (1)
   7. Archaeon Sulfolobus solfataricus [TaxId: 2287] [51806] (1)
   8. Archaeon Methanothermus fervidus [TaxId: 2180] [51807] (1)
   9. Trypanosoma brucei brucei, glycosome [TaxId: 5702] [51808] (1)
   10. Trypanosoma cruzi [TaxId: 5693] [75104] (7)
   11. Leishmania mexicana [TaxId: 5665] [51809] (5)
   12. American lobster (Homarus americanus) [TaxId: 6706] [51810] (2)
   13. South China Sea lobster (Palinurus versicolor) [TaxId: 150436] [51811] (5)
   14. Human (Homo sapiens) [TaxId: 9606] [51812] (1)
   15. Rabbit (Oryctolagus cuniculus) [TaxId: 9986] [102158] (1)
   16. Spinach (Spinacia oleracea) [TaxId: 3562] [69409] (24)
       SQ P19866
   17. Human(Homo sapiens), liver isoform [TaxId: 9606] [141915] (8)
       SQ P04406 2-150,315-334
   18. Malaria parasite (Plasmodium falciparum) [TaxId: 5833] [141916] (12)
       SQ Q8IKK7 4-152,319-335! SQ Q8T6B1 1-152,319-337
   19. Archaeon Pyrococcus horikoshii [TaxId: 53953] [159423] (4)
       SQ O59494 1-139,302-334
2. Aspartate beta-semialdehyde dehydrogenase [51813]
   1. Escherichia coli [TaxId: 562] [51814] (4)
      SQ P00353
   2. Vibrio cholerae [TaxId: 666] [82297] (2)
   3. Haemophilus influenzae [TaxId: 727] [102159] (12)
      SQ P44801
   4. Streptococcus pneumoniae [TaxId: 1313] [141917] (11)
      SQ Q8DQ00 2-127,330-357
3. Acetaldehyde dehydrogenase (acylating) [89527]
   1. Pseudomonas sp. [TaxId: 306] [89528] (1)
4. Homoserine dehydrogenase [51815]
   1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [51816] (4)
      SQ P31116
5. Saccharopine reductase [51817]
   1. Rice blast fungus (Magnaporthe grisea) [TaxId: 148305] [51818] (3)
6. Diaminopimelic acid dehydrogenase (DAPDH) [51819]
   1. Corynebacterium glutamicum [TaxId: 1718] [51820] (4)
7. Dihydrodipicolinate reductase [51821]
   1. Escherichia coli [TaxId: 562] [51822] (5)
   2. Mycobacterium tuberculosis [TaxId: 1773] [102160] (14)
   3. Thermotoga maritima [TaxId: 2336] [110417] (1)
      SQ Q9X1K8
8. Myo-inositol 1-phosphate synthase [75105]
   1. Mycobacterium tuberculosis [TaxId: 1773] [75106] (1)
   2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [75107] (9)
      SQ P11986
   3. Archaeoglobus fulgidus [TaxId: 2234] [110418] (1)
      SQ O28480
   4. Caenorhabditis elegans [TaxId: 6239] [110419] (1)
      SQ Q18664
9. Hypothetical protein TM1419 [102161]
   myo-inositol 1-phosphate synthase-related protein
   1. Thermotoga maritima [TaxId: 2336] [102162] (1)
10. Hypothetical protein TM1643 [75108]
    1. Thermotoga maritima [TaxId: 2336] [75109] (2)
11. 1-deoxy-D-xylulose-5-phosphate reductoisomerase [69410]
    1. Escherichia coli [TaxId: 562] [69411] (12)
       SQ P45568
    2. Zymomonas mobilis [TaxId: 542] [110420] (2)
       SQ Q9X5F2
12. Biliverdin reductase [51823]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [51824] (3)
13. Glucose-fructose oxidoreductase, N-terminal domain [51825]
    1. Zymomonas mobilis [TaxId: 542] [51826] (12)
14. Glucose 6-phosphate dehydrogenase, N-terminal domain [51827]
    1. Leuconostoc mesenteroides [TaxId: 1245] [51828] (9)
    2. Human (Homo sapiens) [TaxId: 9606] [51829] (1)
15. Virulence factor MviM [110421]
    1. Escherichia coli [TaxId: 562] [110422] (1)
       SQ P75931
16. N-acetyl-gamma-glutamyl-phosphate reductase ArgC [110423]
    1. Thermotoga maritima [TaxId: 2336] [110424] (1)
       SQ Q9X2A2
    2. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117428] (5)
       SQ O82187 15-359
    3. Salmonella typhimurium [TaxId: 90371] [141918] (1)
       SQ Q8ZKL8 1-153,309-334
17. Putative oxidoreductase VCA1048 [110425]
    1. Vibrio cholerae [TaxId: 666] [110426] (1)
       SQ Q9KKQ4
18. Probable oxidoreductase At4g09670 [117429]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117430] (1)
       SQ Q9SZ83
19. Putative semialdehyde dehydrogenase [141919]
    1. Rice (Oryza sativa) [TaxId: 4530] [141920] (4)
       SQ Q6AV34 68-218,384-415
20. Galactose/lactose metabolism regulatory protein GAL80 [141921]
    1. Yeast (Kluyveromyces lactis) [TaxId: 28985] [141922] (9)
       SQ Q06433 2-154,374-457
21. Usg-1 protein homolog PA3116 [141923]
    1. Pseudomonas aeruginosa [TaxId: 287] [141924] (1)
       SQ O87014 3-129,320-336
22. Hypothetical protein TM0312 [141925]
    1. Thermotoga maritima [TaxId: 2336] [141926] (2)
       SQ Q9WYE8 4-131,276-328

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk