Structural Classification of Proteins
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Family: Alcohol dehydrogenase-like, C-terminal domain

N-terminal all-beta domain defines family

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: NAD(P)-binding Rossmann-fold domains [51734]
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. Superfamily: NAD(P)-binding Rossmann-fold domains [51735]
    link to SUPERFAMILY database - Superfamily
  5. Family: Alcohol dehydrogenase-like, C-terminal domain [51736]
    N-terminal all-beta domain defines family

Protein Domains:

  1. Alcohol dehydrogenase [51737]
    1. Horse (Equus caballus) [TaxId: 9796] [51738] (38) picpic
      SQ P00327
    2. Human (Homo sapiens), different isozymes [TaxId: 9606] [51739] (26) picpic
      SQ P00326 ! SQ P00325 ! SQ P07327
    3. Mouse (Mus musculus), class II [TaxId: 10090] [51740] (3) picpic
    4. Frog (Rana perezi) [TaxId: 8403] [89511] (2) picpic
    5. Cod (Gadus callarias) [TaxId: 8053] [51741] (1) picpic
    6. Archaeon Sulfolobus solfataricus [TaxId: 2287] [82286] (4) picpic
    7. Archaeon Aeropyrum pernix [TaxId: 56636] [102121] (1) picpic
    8. Pseudomonas aeruginosa [TaxId: 287] [102122] (1) picpic
    9. Bacillus stearothermophilus [TaxId: 1422] [102123] (1) picpic
  2. Hypothetical protein TM0436 [102124]
    1. Thermotoga maritima [TaxId: 2336] [102125] (1) picpic
  3. Hypothetical protein YhdH [102126]
    1. Escherichia coli [TaxId: 562] [102127] (2) picpic
      SQ P26646
  4. Hypothetical protein YahK [102128]
    1. Escherichia coli [TaxId: 562] [102129] (1) picpic
  5. Benzyl alcohol dehydrogenase [89512]
    1. Acinetobacter calcoaceticus [TaxId: 471] [89513] (1) picpic
  6. Bacterial secondary alcohol dehydrogenase [51742]
    1. Clostridium beijerinckii [TaxId: 1520] [51743] (3) picpic
    2. Thermoanaerobacter brockii [TaxId: 29323] [51744] (10) picpic
  7. Ketose reductase (sorbitol dehydrogenase) [51745]
    1. Silverleaf whitefly (Bemisia argentifolii) [TaxId: 77855] [51746] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [102130] (3) picpic
  8. Formaldehyde dehydrogenase [82287]
    1. Pseudomonas putida [TaxId: 303] [82288] (1) picpic
  9. Quinone oxidoreductase [51747]
    1. Escherichia coli [TaxId: 562] [51748] (1) picpic
    2. Thermus thermophilus [TaxId: 274] [89514] (2) picpic
    3. Human (Homo sapiens) [TaxId: 9606] [117402] (1) picpic
      SQ Q08257
  10. Putative enoyl reductase domain of polyketide synthase [89515]
    1. Mycobacterium tuberculosis [TaxId: 1773] [89516] (1) picpic
  11. 2,4-dienoyl-CoA reductase [89517]
    1. Yeast (Candida tropicalis) [TaxId: 5482] [89518] (5) picpic
  12. Putative zinc-binding alcohol dehydrogenase [102131]
    1. Mouse (Mus musculus) [TaxId: 10090] [102132] (1) picpic
  13. Cinnamyl alcohol dehydrogenase, ADH6 [110403]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110404] (3) picpic
      SQ Q04894
  14. Leukotriene b4 12-hydroxydehydrogenase/prostaglandin 15-keto reductase [110405]
    1. Guinea pig (Cavia porcellus) [TaxId: 10141] [110406] (5) picpic
      SQ Q9EQZ5
  15. B. subtilis YhfP homologue [117403]
    1. Bacillus stearothermophilus [TaxId: 1422] [117404] (1) picpic
      SQ Q5L022; 96% sequence identity; Geobacillus kaustophilus TaxID:1462
  16. Hypothetical protein YhfP [117405]
    1. Bacillus subtilis [TaxId: 1423] [117406] (2) picpic
      SQ O07615
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk