Structural Classification of Proteins
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Superfamily: alpha/beta-Hydrolases

many members have left-handed crossover connection between strand 8 and additional strand 9
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: alpha/beta-Hydrolases [53473]
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. Superfamily: alpha/beta-Hydrolases [53474]
    many members have left-handed crossover connection between strand 8 and additional strand 9
    link to SUPERFAMILY database - Superfamily

Families:

  1. Acetylcholinesterase-like [53475] (11) picpic
  2. Carboxylesterase [53487] (9) picpic
  3. Mycobacterial antigens [53491] (4) picpic
  4. Hypothetical protein TT1662 [102616] (1) picpic
  5. PepX catalytic domain-like [69581] (4) picpic
  6. Prolyl oligopeptidase, C-terminal domain [53496] (1) picpic
    N-terminal domain is a 7-bladed beta-propeller
  7. DPP6 catalytic domain-like [82497] (3) picpic
    N-terminal domain is a 8-bladed beta-propeller
  8. Serine carboxypeptidase-like [53499] (5) picpic
  9. Gastric lipase [53506] (2) picpic
  10. Proline iminopeptidase-like [53509] (3) picpic
  11. Acetyl xylan esterase-like [82504] (2) picpic
    Pfam 05448; AXE1
  12. Haloalkane dehalogenase [53513] (3) picpic
  13. Dienelactone hydrolase [53518] (2) picpic
  14. Carbon-carbon bond hydrolase [53522] (4) picpic
    closely related to the Proline iminopeptidase-like family
  15. Biotin biosynthesis protein BioH [82509] (1) picpic
  16. Aclacinomycin methylesterase RdmC [102620] (1) picpic
  17. Carboxylesterase/lipase [102623] (1) picpic
  18. Epoxide hydrolase [53525] (4) picpic
  19. Haloperoxidase [53531] (7) picpic
  20. Thioesterases [53542] (3) picpic
  21. Carboxylesterase/thioesterase 1 [53547] (5) picpic
  22. Ccg1/TafII250-interacting factor B (Cib) [75285] (1) picpic
  23. A novel bacterial esterase [53552] (1) picpic
  24. Lipase [53555] (1) picpic
  25. Fungal lipases [53558] (12) picpic
  26. Bacterial lipase [53570] (7) picpic
    lack the first two strands of the common fold
  27. Pancreatic lipase, N-terminal domain [53577] (6) picpic
  28. Hydroxynitrile lyase-like [53585] (3) picpic
  29. Thioesterase domain of polypeptide, polyketide and fatty acid synthases [69584] (4) picpic
    Pfam 00975
  30. Cutinase-like [52260] (3) picpic
    minimal alpha/beta hydrolase lacking peripheral secondary structures; similar to a flavodoxin-like fold
  31. YdeN-like [110699] (1) picpic
    Pfam 06821; DUF1234; lack the first two strands of the common fold
  32. Putative serine hydrolase Ydr428c [110702] (1) picpic
  33. Acylamino-acid-releasing enzyme, C-terminal donain [117711] (1) picpic
    closely related to the prolyl peptidase and DPP6 domains (scop_fa 53496 and 82497)
  34. Hypothetical esterase YJL068C [117714] (1) picpic
    part of Pfam 00756
  35. Hypothetical protein VC1974 [117717] (1) picpic
  36. Atu1826-like [159742] (2) picpic
  37. PHB depolymerase-like [159747] (1) picpic
  38. IroE-like [159750] (1) picpic
  39. TTHA1544-like [159753] (1) picpic
    minimal hydrolase fold (one strand less than the cutinase-like family); there is neither catalytic triad, nor nucleopilic residue in the elbow motif
  40. O-acetyltransferase [159756] (3) picpic
  41. 2,6-dihydropseudooxynicotine hydrolase-like [159762] (1) picpic
    Pfam 06500; DUF1100
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk