Structural Classification of Proteins
Family: Acetylcholinesterase-like
Lineage:
Root:
scop
Class:
Alpha and beta proteins (a/b)
[51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold:
alpha/beta-Hydrolases
[53473]
core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
Superfamily:
alpha/beta-Hydrolases
[53474]
many members have left-handed crossover connection between strand 8 and additional strand 9
uperfamily
Family:
Acetylcholinesterase-like
[53475]
Protein Domains:
Acetylcholinesterase [53476]
Pacific electric ray (Torpedo californica)
[TaxId: 7787]
[53477] (79)
SQ
P04058
25-556
1ea5
complexed with nag
chain a
[34592]
2c5g
automatically matched to d1eve__
complexed with cl, etm, nag, pge
region a:4-535
[129915]
1e66
complexed with hux, nag
chain a
[59291]
1gpk
complexed with hup, nag
chain a
[76260]
2c4h
automatically matched to d1eve__
complexed with ace, act, at3, cl, nag, ndg, pge
region a:4-535
[129815]
2cek
automatically matched to d1eve__
complexed with mes, n8t, nag, ndg, pge
region a:4-535
[130347]
1qid
chain a
[34593]
1w6r
complexed with gnt, mg, nag
chain a
[114283]
1jjb
complexed with nag, pe7
chain a
[71695]
1w4l
complexed with gl8, nag
chain a
[114192]
1h23
complexed with e12, nag, ndg
chain a
[76515]
1h22
complexed with e10, nag
chain a
[76514]
1gqr
complexed with emm, nag, saf
chain a
[70374]
2c58
automatically matched to d1eve__
complexed with at3, cl, etm, nag, pge
region a:4-535
[129891]
1qie
chain a
[34594]
1qif
chain a
[34596]
2vjc
automatically matched to d1evea_
complexed with ccd, chh, cl, nag, pge
region a:4-535
[153190]
2vjc
automatically matched to d1evea_
complexed with ccd, chh, cl, nag, pge
region b:4-535
[153191]
1zgc
automatically matched to d1eve__
complexed with a2e, nag
region a:4-535
[125024]
1zgc
automatically matched to d1eve__
complexed with a2e, nag
region b:4-535
[125025]
1vxr
chain a
[34595]
2vja
automatically matched to d1evea_
complexed with ccd, cl, nag, pge
region a:4-535
[153186]
2vja
automatically matched to d1evea_
complexed with ccd, cl, nag, pge
region b:4-535
[153187]
2vjd
automatically matched to d1evea_
complexed with ccd, cl, nag, pge
region a:4-535
[153192]
2vjd
automatically matched to d1evea_
complexed with ccd, cl, nag, pge
region b:4-535
[153193]
1odc
automatically matched to d1eve__
complexed with a8b, nag
region a:4-535
[118700]
2vjb
automatically matched to d1evea_
complexed with ccd, cl, nag, pge
region a:4-535
[153188]
2vjb
automatically matched to d1evea_
complexed with ccd, cl, nag, pge
region b:4-535
[153189]
1zgb
automatically matched to d1eve__
complexed with a1e, nag
region a:4-535
[125023]
2ckm
automatically matched to d1eve__
complexed with aa7, nag
region a:4-535
[130567]
1qig
chain a
[34598]
1gpn
complexed with hub, nag
chain a
[76261]
2vt7
automatically matched to d1evea_
complexed with cl, nag, pge
region a:4-535
[153540]
2vt7
automatically matched to d1evea_
complexed with cl, nag, pge
region b:4-535
[153541]
1som
complexed with nag, som
chain a
[34584]
2c5f
automatically matched to d1eve__
complexed with chh, nag, ndg, nwa, pge
region a:4-535
[129914]
1eve
complexed with e20, nag
chain a
[34585]
2bag
automatically matched to d1eve__
complexed with 1pe, gsg, mes, nag
region a:4-535
[128236]
2va9
automatically matched to d1evea_
complexed with nag
region a:4-535
[152824]
2va9
automatically matched to d1evea_
complexed with nag
region b:4-535
[152825]
2vt6
automatically matched to d1evea_
complexed with cl, nag, pge
region a:4-535
[153538]
2vt6
automatically matched to d1evea_
complexed with cl, nag, pge
region b:4-535
[153539]
2dfp
complexed with mes, nag
chain a
[34597]
1dx6
chain a
[34602]
1vxo
chain a
[34599]
1qih
chain a
[34600]
1ut6
automatically matched to d1eve__
complexed with a8n, nag
region a:4-535
[119698]
1hbj
complexed with fbq, mes, nag, pg4
chain a
[65785]
1u65
automatically matched to d1eve__
complexed with cp0, fuc, ful, iod, man, nag, ndg
region a:4-535
[119563]
2v96
automatically matched to d1evea_
complexed with cfq, nag
region a:4-535
[152797]
2v96
automatically matched to d1evea_
complexed with cfq, nag
region b:4-535
[152798]
2ack
complexed with edr
chain a
[34581]
1w75
complexed with nag
chain a
[114313]
chain b
[114314]
1cfj
complexed with gb, nag
chain a
[34586]
1w76
complexed with gnt, nag
chain a
[114315]
chain b
[114316]
1qii
chain a
[34603]
2ace
complexed with ach
chain a
[34582]
1vot
complexed with hup
chain a
[34583]
2j3d
automatically matched to d1evea_
complexed with mg, nag
region a:4-535
[147858]
1qij
chain a
[34604]
2cmf
automatically matched to d1eve__
complexed with f11, nag
region a:4-535
[130629]
1qti
chain a
[34601]
1qik
chain a
[34606]
2j3q
automatically matched to d1evea_
complexed with mg, nag, ndg, tfl
region a:4-535
[147859]
1qim
chain a
[34605]
2v97
automatically matched to d1evea_
complexed with cfq, cl, nag
region a:4-535
[152799]
2v97
automatically matched to d1evea_
complexed with cfq, cl, nag
region b:4-535
[152800]
1acj
complexed with tha
chain a
[34588]
1ax9
complexed with edr
chain a
[34589]
1amn
complexed with naf, so4
chain a
[34587]
2j4f
automatically matched to d1eve__
complexed with hg
region a:4-535
[138002]
2vq6
automatically matched to d1evea_
complexed with fp1, nag, so4
region a:4-535
[153425]
1gqs
complexed with nag, saf
chain a
[70375]
1fss
complexed with nag, zn
chain a
[34608]
1acl
complexed with dme
chain a
[34590]
1e3q
complexed with ebw, nag, so4
chain a
[34607]
2v98
automatically matched to d1evea_
complexed with cfq, cl, nag
region a:4-535
[152801]
2v98
automatically matched to d1evea_
complexed with cfq, cl, nag
region b:4-535
[152802]
1oce
complexed with mf2
chain a
[34591]
Electric eel (Electrophorus electricus)
[TaxId: 8005]
[53478] (3)
1eea
chain a
[34609]
1c2o
chain a
[34610]
chain b
[34611]
chain c
[34612]
chain d
[34613]
1c2b
chain a
[34614]
Mouse (Mus musculus)
[TaxId: 10090]
[53479] (31)
2ha2
automatically matched to d1j06a_
complexed with fuc, nag, p6g, sck, scu
region a:1-542
[136274]
2ha2
automatically matched to d1j06a_
complexed with fuc, nag, p6g, sck, scu
region b:4-542
[136275]
2ha0
automatically matched to d1j06a_
complexed with chh, fuc, iod, nag, nwa, p6g
region a:3-542
[136272]
2ha0
automatically matched to d1j06a_
complexed with chh, fuc, iod, nag, nwa, p6g
region b:4-542
[136273]
2ha3
automatically matched to d1j06a_
complexed with cht, fuc, nag, p6g
region a:1-542
[136276]
2ha3
automatically matched to d1j06a_
complexed with cht, fuc, nag, p6g
region b:4-542
[136277]
1n5m
complexed with co3, fuc, gmn, iod, nag, p6g, pg4
chain a
[80031]
chain b
[80032]
2gyu
automatically matched to d1j06a_
complexed with fuc, hi6, nag, p4g, p6g
region a:1-542
[135873]
2gyu
automatically matched to d1j06a_
complexed with fuc, hi6, nag, p4g, p6g
region b:4-542
[135874]
2h9y
automatically matched to d1j06a_
complexed with fuc, naf, nag, p6g, pg4
region a:1-542
[136270]
2h9y
automatically matched to d1j06a_
complexed with fuc, naf, nag, p6g, pg4
region b:4-542
[136271]
1n5r
complexed with acy, fuc, nag, p6g, pg4, prm
chain a
[80037]
chain b
[80038]
1q84
complexed with nag, p6g, tz4
chain a
[96156]
chain b
[96157]
1j07
complexed with cl, co3, dcu, fuc, nag, p6g, pg4
chain a
[77023]
chain b
[77024]
1j06
complexed with co3, fuc, nag, p6g, pg4, pge
chain a
[77021]
chain b
[77022]
2c0p
automatically matched to d1j06a_
complexed with atj
region a:1-542
[129600]
2c0p
automatically matched to d1j06a_
complexed with atj
region b:4-542
[129601]
2gyw
automatically matched to d1j06a_
complexed with co3, fuc, nag, obi, p6g
region a:1-542
[135877]
2gyw
automatically matched to d1j06a_
complexed with co3, fuc, nag, obi, p6g
region b:4-542
[135878]
2c0q
automatically matched to d1j06a_
complexed with ntj, p6g
region a:1-542
[129602]
2c0q
automatically matched to d1j06a_
complexed with ntj, p6g
region b:4-542
[129603]
1q83
complexed with ful, nag, p6g, tz5
chain a
[96154]
chain b
[96155]
2gyv
automatically matched to d1j06a_
complexed with co3, hbp, nag, p3g
region a:1-542
[135875]
2gyv
automatically matched to d1j06a_
complexed with co3, hbp, nag, p3g
region b:4-542
[135876]
1ku6
complexed with edo, nag
chain a
[91037]
2jgm
automatically matched to d1j06a_
complexed with nag
region a:1-542
[138312]
2jgm
automatically matched to d1j06a_
complexed with nag
region b:4-540
[138313]
2jey
automatically matched to d1j06a_
complexed with hlo, p6g
region a:1-542
[148026]
2jey
automatically matched to d1j06a_
complexed with hlo, p6g
region b:4-542
[148027]
1maa
complexed with dme, fuc, gol, nag, po4
chain a
[34615]
chain b
[34616]
chain c
[34617]
chain d
[34618]
1mah
complexed with nag
chain a
[34619]
Human (Homo sapiens)
[TaxId: 9606]
[53480] (2)
1f8u
complexed with nag; mutant
chain a
[34620]
1b41
complexed with fuc, nag; mutant
chain a
[34621]
Fruit fly (Drosophila melanogaster)
[TaxId: 7227]
[53481] (3)
1dx4
complexed with 760, bma, nag, so4
chain a
[34622]
1qon
complexed with bma, i40, nag, so4
chain a
[34623]
1qo9
complexed with bma, nag
chain a
[34624]
Butyryl cholinesterase [102612]
Human (Homo sapiens)
[TaxId: 9606]
[102613] (9)
1p0i
complexed with bua, cl, fuc, gol, mes, nag, sul; mutant
chain a
[93867]
1xlw
automatically matched to d1p0ia_
complexed with cl, dep, fuc, ful, gol, nag, s, so4; mutant
region a:4-529
[122139]
1xlu
automatically matched to d1p0ia_
complexed with cl, ful, gol, mip, nag, s, so4; mutant
region a:4-529
[122137]
1xlv
automatically matched to d1p0ia_
complexed with cl, efs, ful, gol, nag, s, so4; mutant
region a:4-529
[122138]
1p0p
complexed with bch, cl, fuc, gol, nag, som, sul; mutant
chain a
[93869]
1p0q
complexed with cl, fuc, gol, nag, som, sul; mutant
chain a
[93870]
1p0m
complexed with cht, cl, fuc, gol, mes, nag, sul; mutant
chain a
[93868]
2pm8
automatically matched to d1p0ia_
complexed with gol, nag, ndg, so4
region a:4-529
[149655]
2pm8
automatically matched to d1p0ia_
complexed with gol, nag, ndg, so4
region b:4-529
[149656]
Bile-salt activated lipase (cholesterol esterase) [53482]
Cow (Bos taurus)
[TaxId: 9913]
[53483] (3)
2bce
mutant
chain a
[34625]
1akn
complexed with nag
chain a
[34626]
1aql
complexed with nag, tch
chain a
[34627]
chain b
[34628]
Human (Homo sapiens)
[TaxId: 9606]
[53484] (2)
1f6w
mutant
chain a
[34629]
1jmy
truncated recombinant enzyme
complexed with so4
chain a
[63182]
Mammalian carboxylesterase (liver carboxylesterase I) [75282]
Rabbit (Oryctolagus cuniculus)
[TaxId: 9986]
[75283] (1)
1k4y
complexed with 4pn, man, nag
chain a
[72069]
Human (Homo sapiens)
[TaxId: 9606]
[89768] (48)
2h7c
automatically matched to d1mx9d_
complexed with coa, nag, ndg, sia, so4
region a:1021-1553
[136207]
2h7c
automatically matched to d1mx9d_
complexed with coa, nag, ndg, sia, so4
region b:2022-2553
[136208]
2h7c
automatically matched to d1mx9d_
complexed with coa, nag, ndg, sia, so4
region c:3022-3553
[136209]
2h7c
automatically matched to d1mx9d_
complexed with coa, nag, ndg, sia, so4
region d:4021-4553
[136210]
2h7c
automatically matched to d1mx9d_
complexed with coa, nag, ndg, sia, so4
region e:5022-5553
[136211]
2h7c
automatically matched to d1mx9d_
complexed with coa, nag, ndg, sia, so4
region f:6022-6553
[136212]
1mx1
complexed with nag, sia, tha
chain a
[85165]
chain b
[85166]
chain c
[85167]
chain d
[85168]
chain e
[85169]
chain f
[85170]
2hrr
automatically matched to d1mx9d_
complexed with nag, ntj, sia, so4, suc
region a:1021-1553
[136696]
2hrr
automatically matched to d1mx9d_
complexed with nag, ntj, sia, so4, suc
region b:2022-2553
[136697]
2hrr
automatically matched to d1mx9d_
complexed with nag, ntj, sia, so4, suc
region c:3022-3553
[136698]
2hrq
automatically matched to d1mx9d_
complexed with gd7, nag, sia, so4, suc
region a:1021-1553
[136690]
2hrq
automatically matched to d1mx9d_
complexed with gd7, nag, sia, so4, suc
region b:2022-2553
[136691]
2hrq
automatically matched to d1mx9d_
complexed with gd7, nag, sia, so4, suc
region c:3022-3553
[136692]
2hrq
automatically matched to d1mx9d_
complexed with gd7, nag, sia, so4, suc
region d:4021-4553
[136693]
2hrq
automatically matched to d1mx9d_
complexed with gd7, nag, sia, so4, suc
region e:5022-5553
[136694]
2hrq
automatically matched to d1mx9d_
complexed with gd7, nag, sia, so4, suc
region f:6022-6553
[136695]
1mx5
complexed with cl, htq, nag, sia
chain a
[85171]
chain b
[85172]
chain c
[85173]
chain d
[85174]
chain e
[85175]
chain f
[85176]
2dqz
automatically matched to d1mx9d_
complexed with coa, f, htq, nag, plm, sia, so4
region a:1021-1553
[131647]
2dqz
automatically matched to d1mx9d_
complexed with coa, f, htq, nag, plm, sia, so4
region b:2021-2553
[131648]
2dqz
automatically matched to d1mx9d_
complexed with coa, f, htq, nag, plm, sia, so4
region c:3021-3553
[131649]
1yah
automatically matched to d1mx9d_
complexed with eee, nag, sia, so4
region a:22-553
[122818]
1yah
automatically matched to d1mx9d_
complexed with eee, nag, sia, so4
region b:22-553
[122819]
1yah
automatically matched to d1mx9d_
complexed with eee, nag, sia, so4
region c:22-553
[122820]
1ya8
automatically matched to d1mx9d_
complexed with mvb, nag, sia, smb, so4
region a:22-553
[122804]
1ya8
automatically matched to d1mx9d_
complexed with mvb, nag, sia, smb, so4
region b:22-553
[122805]
1ya8
automatically matched to d1mx9d_
complexed with mvb, nag, sia, smb, so4
region c:22-553
[122806]
1mx9
complexed with nag, nlx
chain a
[85179]
chain b
[85180]
chain c
[85181]
chain d
[85182]
chain e
[85183]
chain f
[85184]
chain g
[85185]
chain h
[85186]
chain i
[85187]
chain j
[85188]
chain k
[85189]
chain l
[85190]
2dr0
automatically matched to d1mx9d_
complexed with nag, sia, so4, tch
region a:1021-1553
[131650]
2dr0
automatically matched to d1mx9d_
complexed with nag, sia, so4, tch
region b:2021-2553
[131651]
2dr0
automatically matched to d1mx9d_
complexed with nag, sia, so4, tch
region c:3021-3553
[131652]
2dqy
automatically matched to d1mx9d_
complexed with chd, nag, plm, sia, so4
region a:1021-1553
[131644]
2dqy
automatically matched to d1mx9d_
complexed with chd, nag, plm, sia, so4
region b:2021-2553
[131645]
2dqy
automatically matched to d1mx9d_
complexed with chd, nag, plm, sia, so4
region c:3021-3553
[131646]
1ya4
automatically matched to d1mx9d_
complexed with ctx, nag, sia, so4
region a:22-553
[122787]
1ya4
automatically matched to d1mx9d_
complexed with ctx, nag, sia, so4
region b:22-553
[122788]
1ya4
automatically matched to d1mx9d_
complexed with ctx, nag, sia, so4
region c:22-553
[122789]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region a:22-553
[122821]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region b:22-553
[122822]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region c:22-553
[122823]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region d:22-553
[122824]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region e:22-553
[122825]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region f:22-553
[122826]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region g:22-553
[122827]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region h:22-553
[122828]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region i:22-553
[122829]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region j:22-553
[122830]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region k:22-553
[122831]
1yaj
automatically matched to d1mx9d_
complexed with bez, nag, sia, so4
region l:22-553
[122832]
Thermophilic para-nitrobenzyl esterase (PNB esterase) [53485]
Bacillus subtilis
[TaxId: 1423]
[53486] (3)
1qe3
complexed with so4, zn
chain a
[34630]
1c7j
complexed with k, so4; mutant
chain a
[34631]
1c7i
complexed with ca; mutant
chain a
[34632]
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Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright
© 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk