Structural Classification of Proteins
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Family: beta-N-acetylhexosaminidase catalytic domain

Glycosyl hydrolase family 20, GH20

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: TIM beta/alpha-barrel [51350]
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily: (Trans)glycosidases [51445]
    link to SUPERFAMILY database - Superfamily
  5. Family: beta-N-acetylhexosaminidase catalytic domain [51550]
    Glycosyl hydrolase family 20, GH20

Protein Domains:

  1. Bacterial chitobiase (beta-N-acetylhexosaminidase) [51551]
    1. Serratia marcescens [TaxId: 615] [51552] (4)
      1. 1qba picpicxrefxrefxref
        complexed with so4
        1. region a:338-780 [29009] picpiclink
      2. 1c7s picpicxrefxrefxref
        complexed with cbs, so4; mutant
        1. region a:338-780 [29011] picpiclink
      3. 1qbb picpicxrefxrefxref
        complexed with cbs, so4
        1. region a:338-780 [29010] picpiclink
      4. 1c7t picpicxrefxrefxref
        complexed with cbs, so4; mutant
        1. region a:338-780 [29012] picpiclink
  2. beta-N-acetylhexosaminidase [63915]
    1. Streptomyces plicatus [TaxId: 1922] [63916] (6)
      1. 1jak picpicxref
        complexed with cl, gol, ifg, so4
        1. region a:151-506 [66472] picpiclink
      2. 1m03 picpicxref
        complexed with cl, gol, nag, so4; mutant
        1. region a:151-506 [78322] picpiclink
      3. 1m04 picpicxref
        complexed with cl, gol, nag, so4; mutant
        1. region a:151-506 [78324] picpiclink
      4. 1hp5 picpicxref
        complexed with cl, gol, ngt, so4
        1. region a:151-506 [61113] picpiclink
      5. 1m01 picpicxref
        complexed with cl, gol, nag, so4
        1. region a:151-506 [78320] picpiclink
      6. 1hp4 picpicxref
        complexed with cl, gol, so4
        1. region a:151-506 [61111] picpiclink
  3. beta-hexosaminidase B [89486]
    1. Human (Homo sapiens) [TaxId: 9606] [89487] (12)
      1. 1now picpicxref
        complexed with gol, ifg, nag, so4
        1. region a:200-552 [85936] picpiclink
        2. region b:200-552 [85938] picpiclink
      2. 1o7a picpicxref
        complexed with edo, gdl, nag
        1. region a:200-554 [92608] picpiclink
        2. region b:200-554 [92610] picpiclink
        3. region c:200-554 [92612] picpiclink
        4. region d:200-553 [92614] picpiclink
        5. region e:200-554 [92616] picpiclink
        6. region f:200-554 [92618] picpiclink
      3. 1nou picpicxref
        complexed with gol, nag, so4
        1. region a:200-552 [85932] picpiclink
        2. region b:200-552 [85934] picpiclink
      4. 1np0 picpicxref
        complexed with gol, nag, ngt, so4
        1. region a:200-552 [85940] picpiclink
        2. region b:200-552 [85942] picpiclink
      5. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ndg, so4
        1. region b:200-552 [135311] picpiclink
      6. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ndg, so4
        1. region c:200-552 [135313] picpiclink
      7. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ndg, so4
        1. region f:200-552 [135315] picpiclink
      8. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ndg, so4
        1. region g:200-552 [135317] picpiclink
      9. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ngt
        1. region b:200-552 [135319] picpiclink
      10. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ngt
        1. region d:200-552 [135321] picpiclink
      11. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ngt
        1. region f:200-552 [135323] picpiclink
      12. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1o7aa1
        complexed with bma, nag, ngt
        1. region h:200-552 [135325] picpiclink
  4. Dispersin B, DspB [141788]
    N-acetyl-beta-hexosaminidase
    1. Actinobacillus actinomycetemcomitans [TaxId: 714] [141789] (1)
      SQ Q840G9 16-359
      1. 1yht picpic
        complexed with acy, gol
        1. region a:16-359 [123213] picpiclink
  5. beta-hexosaminidase A [159387]
    1. Human (Homo sapiens) [TaxId: 9606] [159388] (8)
      SQ P06865 167-528
      1. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        complexed with bma, nag, ndg, so4
        1. region a:167-528 [145202] picpiclink
      2. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ndg, so4
        1. region d:167-528 [145204] picpiclink
      3. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ndg, so4
        1. region e:167-528 [145206] picpiclink
      4. 2gjx picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ndg, so4
        1. region h:167-528 [145208] picpiclink
      5. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ngt
        1. region a:167-528 [145210] picpiclink
      6. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ngt
        1. region c:167-528 [145212] picpiclink
      7. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ngt
        1. region e:167-528 [145214] picpiclink
      8. 2gk1 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to 2GJX A:167-528
        complexed with bma, nag, ngt
        1. region g:167-528 [145216] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk