Structural Classification of Proteins
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Family: Histidine biosynthesis enzymes

structural evidence for the gene duplication within the barrel fold

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: TIM beta/alpha-barrel [51350]
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily: Ribulose-phoshate binding barrel [51366]
    link to SUPERFAMILY database - Superfamily
  5. Family: Histidine biosynthesis enzymes [51367]
    structural evidence for the gene duplication within the barrel fold

Protein Domains:

  1. Phosphoribosylformimino-5-aminoimidazole carboxamide ribotite isomerase HisA [51368]
    1. Thermotoga maritima [TaxId: 2336] [51369] (1) picpic
    2. Streptomyces coelicolor [TaxId: 1902] [141744] (2) picpic
      SQ P16250 2-240
  2. Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF [51370]
    1. Thermotoga maritima [TaxId: 2336] [51371] (4) picpic
    2. Thermus thermophilus [TaxId: 274] [82237] (1) picpic
    3. Baker's yeast (Saccharomyces cerevisiae), His7 [TaxId: 4932] [69379] (4) picpic
    4. Archaeon Pyrobaculum aerophilum [TaxId: 13773] [69380] (1) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk