Structural Classification of Proteins

Family: Class I DAHP synthetase

Lineage:

Root: scop
Class: Alpha and beta proteins (a/b) [51349]
Mainly parallel beta sheets (beta-alpha-beta units)
Fold: TIM beta/alpha-barrel [51350]
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites
Superfamily: Aldolase [51569]
Common fold covers whole protein structure
uperfamily
Family: Class I DAHP synthetase [51599]

Protein Domains:

3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG) [51600]
1. Escherichia coli, phenylalanine-regulated isozyme [TaxId: 562] [51601] (4)
  1. 1n8f
    complexed with mn, pep, so4; mutant
    1. chain a [85397]
    2. chain b [85398]
    3. chain c [85399]
    4. chain d [85400]
  2. 1gg1
    complexed with mn, pga, so4
    1. chain a [29187]
    2. chain b [29188]
    3. chain c [29189]
    4. chain d [29190]
  3. 1qr7
    complexed with pb, pep, so4
    1. chain a [29191]
    2. chain b [29192]
    3. chain c [29193]
    4. chain d [29194]
  4. 1kfl
    complexed with mn, mse, pep, phe, so4
    1. chain a [72413]
    2. chain b [72414]
    3. chain c [72415]
    4. chain d [72416]
    5. chain e [72417]
    6. chain f [72418]
    7. chain g [72419]
    8. chain h [72420]
2. Baker's yeast (Saccharomyces cerevisiae), tyrosine-regulated isozyme [TaxId: 4932] [82272] (11)
  1. 1of8
    complexed with co, g3p, gol, pep
    1. chain a [92819]
    2. chain b [92820]
  2. 1ofo
    complexed with pga
    1. chain a [92832]
    2. chain b [92833]
  3. 1oab
    complexed with mn, pep
    1. chain a [92702]
    2. chain b [92703]
  4. 1ofa
    complexed with co, gol, pep
    1. chain a [92822]
    2. chain b [92823]
  5. 1ofb
    complexed with gol, mn
    1. chain a [92824]
    2. chain b [92825]
  6. 1hfb
    complexed with pep
    1. chain a [76706]
    2. chain b [76707]
    3. chain c [76708]
    4. chain d [76709]
    5. chain e [76710]
    6. chain f [76711]
    7. chain g [76712]
    8. chain h [76713]
  7. 1of6
    complexed with mn
    1. chain a [92811]
    2. chain b [92812]
    3. chain c [92813]
    4. chain d [92814]
    5. chain e [92815]
    6. chain f [92816]
    7. chain g [92817]
    8. chain h [92818]
  8. 1ofp
    1. chain a [92834]
    2. chain b [92835]
    3. chain c [92836]
    4. chain d [92837]
  9. 1ofq
    complexed with mn
    1. chain a [92838]
    2. chain b [92839]
    3. chain c [92840]
    4. chain d [92841]
  10. 1og0
    complexed with mn, phe; mutant
    1. chain a [92854]
    2. chain b [92855]
    3. chain c [92856]
    4. chain d [92857]
    5. chain e [92858]
    6. chain f [92859]
    7. chain g [92860]
    8. chain h [92861]
  11. 1ofr
    complexed with mn, phe
    1. chain a [92842]
    2. chain b [92843]
    3. chain c [92844]
    4. chain d [92845]
    5. chain e [92846]
    6. chain f [92847]
    7. chain g [92848]
    8. chain h [92849]
3. Thermotoga maritima [TaxId: 2336] [110363] (5)
  SQ Q9WYH8
  1. 1vr6
    automatically matched to d1rzma_
    1. region a:1-338 [120439]
  2. 1vr6
    automatically matched to d1rzma_
    1. region b:1-338 [120440]
  3. 1vr6
    automatically matched to d1rzma_
    1. region c:1-338 [120441]
  4. 1vr6
    automatically matched to d1rzma_
    1. region d:1-338 [120442]
  5. 1rzm
    complexed with cd, e4p, pep
    1. chain a [105137]
    2. chain b [105138]
3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) [51602]
1. Escherichia coli [TaxId: 562] [51603] (10)
  SQ P17579
  1. 1d9e
    complexed with so4
    1. chain a [29195]
    2. chain b [29196]
    3. chain c [29197]
    4. chain d [29198]
  2. 1phw
    complexed with rob
    1. chain a [104155]
  3. 1x8f
    automatically matched to d1d9ea_
    1. region a:1-284 [121804]
  4. 1gg0
    complexed with po4
    1. chain a [29199]
  5. 1g7v
    complexed with pai
    1. chain a [60335]
  6. 1x6u
    automatically matched to d1d9ea_
    complexed with do8
    1. region a:1-284 [121754]
  7. 1q3n
    complexed with pep
    1. chain a [111653]
  8. 1pl9
    complexed with fpe
    1. chain a [104188]
  9. 1phq
    complexed with fpe
    1. chain a [104154]
  10. 1g7u
    complexed with pep
    1. chain a [60334]
2. Haemophilus influenzae [TaxId: 727] [102095] (1)
  1. 1o60
    structural genomics
    1. chain a [92532]
    2. chain b [92533]
    3. chain c [92534]
    4. chain d [92535]
3. Aquifex aeolicus [TaxId: 63363] [63922] (20)
  1. 2a21
    automatically matched to d1pe1a_
    complexed with pep, po4, zn
    1. region a:1002-1264 [126023]
  2. 2a21
    automatically matched to d1pe1a_
    complexed with pep, po4, zn
    1. region b:2003-2264 [126024]
  3. 1pe1
    complexed with 2pg, cd, po4
    1. chain a [94591]
    2. chain b [94592]
  4. 1lrq
    complexed with a5p, cd, pep, po4; mutant
    1. chain a [78163]
    2. chain b [78164]
  5. 1lro
    complexed with cd, pep, po4; mutant
    1. chain a [78161]
    2. chain b [78162]
  6. 1jcx
    complexed with cd, pai
    1. chain a [66510]
    2. chain b [66511]
  7. 1pck
    complexed with cd, pez, po4
    1. chain a [94438]
    2. chain b [94439]
  8. 1fxq
    complexed with a5p, pep
    1. chain a [60108]
    2. chain b [60109]
  9. 1pcw
    complexed with cd, h4p
    1. chain a [94495]
    2. chain b [94496]
  10. 1fxp
    complexed with cd, po4
    1. chain a [60106]
    2. chain b [60107]
  11. 1fws
    complexed with cd, pep, po4
    1. chain a [60063]
    2. chain b [60064]
  12. 1fww
    complexed with a5p, cd, pep, po4
    1. chain a [60067]
    2. chain b [60068]
  13. 1jcy
    complexed with cd, pep, po4, r5p
    1. chain a [66512]
    2. chain b [66513]
  14. 1fwt
    complexed with cd, e4p, pep, po4
    1. chain a [60065]
    2. chain b [60066]
  15. 2a2i
    automatically matched to d1pe1a_
    complexed with a5p, pep, zn
    1. region a:1002-1264 [126031]
  16. 2a2i
    automatically matched to d1pe1a_
    complexed with a5p, pep, zn
    1. region b:2003-2264 [126032]
  17. 1fy6
    complexed with a5p, cd, po4
    1. chain a [60111]
    2. chain b [60112]
  18. 1fwn
    complexed with pep, po4
    1. chain a [60060]
    2. chain b [60061]
  19. 1lrn
    complexed with cd, po4; mutant
    1. chain a [78159]
    2. chain b [78160]
  20. 1fx6
    complexed with po4
    1. chain a [60086]
    2. chain b [60087]