Structural Classification of Proteins
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Family: Single strand DNA-binding domain, SSB

barrel, closed; n=5, S=10

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: OB-fold [50198]
    barrel, closed or partly opened n=5, S=10 or S=8; greek-key
  4. Superfamily: Nucleic acid-binding proteins [50249]
    link to SUPERFAMILY database - Superfamily
  5. Family: Single strand DNA-binding domain, SSB [50263]
    barrel, closed; n=5, S=10

Protein Domains:

  1. ssDNA-binding protein [50264]
    1. Human (Homo sapiens), mitochondria [TaxId: 9606] [50265] (4)
      SQ Q04837
      1. 3ull picpic
        1. chain a [25282] picpiclink
        2. chain b [25283] picpiclink
      2. 1s3o picpic
        1. chain a [105247] picpiclink
        2. chain b [105248] picpiclink
      3. 2dud picpic
        automatically matched to d1s3ob_
        1. region a:12-123 [131749] picpiclink
      4. 2dud picpic
        automatically matched to d1s3ob_
        1. region b:12-123 [131750] picpiclink
    2. Escherichia coli [TaxId: 562] [50266] (5)
      SQ P02339
      1. 1qvc picpic
        1. chain a [25284] picpiclink
        2. chain b [25285] picpiclink
        3. chain c [25286] picpiclink
        4. chain d [25287] picpiclink
      2. 1eyg picpic
        protein/DNA complex
        1. chain a [25292] picpiclink
        2. chain b [25293] picpiclink
        3. chain c [25294] picpiclink
        4. chain d [25295] picpiclink
      3. 1eqq picpic
        complexed with ssDNA
        complexed with 5mu
        1. chain a [90461] picpiclink
        2. chain b [90462] picpiclink
        3. chain c [90463] picpiclink
        4. chain d [90464] picpiclink
      4. 1sru picpic
        1. chain a [105971] picpiclink
        2. chain b [105972] picpiclink
        3. chain c [105973] picpiclink
        4. chain d [105974] picpiclink
      5. 1kaw picpic
        1. chain a [25288] picpiclink
        2. chain b [25289] picpiclink
        3. chain c [25290] picpiclink
        4. chain d [25291] picpiclink
    3. Mycobacterium tuberculosis [TaxId: 1773] [101760] (4)
      1. 1ue1 picpic
        complexed with zn
        1. chain a [99243] picpiclink
        2. chain b [99244] picpiclink
      2. 1ue5 picpic
        complexed with cd
        1. chain a [99245] picpiclink
        2. chain b [99246] picpiclink
      3. 1ue6 picpic
        1. chain a [99247] picpiclink
        2. chain b [99248] picpiclink
        3. chain c [99249] picpiclink
        4. chain d [99250] picpiclink
      4. 1ue7 picpic
        1. chain a [99251] picpiclink
        2. chain b [99252] picpiclink
        3. chain c [99253] picpiclink
        4. chain d [99254] picpiclink
    4. Deinococcus radiodurans [TaxId: 1299] [110194] (1)
      SQ Q9RY51
      1. 1se8 picpic
        1. chain a [105448] picpiclink
  2. Archaeal ssDNA-binding protein [89324]
    similar to the domains of the Replication protein A
    1. Archaeon Sulfolobus solfataricus [TaxId: 2287] [89325] (1)
      1. 1o7i picpic
        complexed with so4
        1. chain a [86642] picpiclink
        2. chain b [86643] picpiclink
  3. Replication protein A 70 KDa subunit (RPA70) [50267]
    duplication: consists of three domains of this fold; contains zinc-finger insert in the C-terminal domain, residues 479-511
    1. Human (Homo sapiens) [TaxId: 9606] [50268] (6)
      1. 2b3g picpic
        automatically matched to d1ewia_
        1. region a:3-114 [127786] picpiclink
      2. 2b29 picpic
        automatically matched to d1ewia_
        1. region a:3-114 [127705] picpiclink
      3. 1jmc picpic
        the N-terminal two domains in complex with ssDNA
        protein/DNA complex
        1. region a:183-298 [25300] picpiclink
        2. region a:299-420 [25301] picpiclink
      4. 1fgu picpic
        the N-terminal two domains free
        1. region a:181-298 [25296] picpiclink
        2. region a:299-426 [25297] picpiclink
        3. region b:181-289 [25298] picpiclink
        4. region b:298-426 [25299] picpiclink
      5. 1l1o picpicxrefxref
        C-terminal domain only
        complexed with zn
        1. chain c [73480] picpiclink
        2. chain f [73483] picpiclink
      6. 1ewi picpic
        N-terminal domain only
        1. chain a [25302] picpiclink
  4. Replication protein A 32 KDa subunit (RPA32) fragment [50269]
    1. Human (Homo sapiens) [TaxId: 9606] [50270] (10)
      1. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1ob_
        complexed with dio
        1. region a:44-171 [149493] picpiclink
      2. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1ob_
        complexed with dio
        1. region b:44-171 [149494] picpiclink
      3. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1ob_
        complexed with dio
        1. region c:44-171 [149495] picpiclink
      4. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1ob_
        complexed with dio
        1. region d:44-171 [149496] picpiclink
      5. 2pqa picpicxrefxref
        automatically matched to d1l1ob_
        1. region a:44-171 [149788] picpiclink
      6. 2pqa picpicxrefxref
        automatically matched to d1l1ob_
        1. region c:44-170 [149790] picpiclink
      7. 1quq picpicxref
        1. chain a [25303] picpiclink
        2. chain c [25304] picpiclink
      8. 2z6k picpicxrefxref
        automatically matched to d1l1ob_
        1. region a:44-171 [154176] picpiclink
      9. 2z6k picpicxrefxref
        automatically matched to d1l1ob_
        1. region b:44-171 [154177] picpiclink
      10. 1l1o picpicxrefxref
        complexed with zn
        1. chain b [73479] picpiclink
        2. chain e [73482] picpiclink
  5. Replication protein A 14 KDa (RPA14) subunit [50271]
    1. Human (Homo sapiens) [TaxId: 9606] [50272] (10)
      1. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1oa_
        complexed with dio
        1. region e:3-117 [149497] picpiclink
      2. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1oa_
        complexed with dio
        1. region f:3-117 [149498] picpiclink
      3. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1oa_
        complexed with dio
        1. region g:3-117 [149499] picpiclink
      4. 2pi2 picpicxrefxrefxrefxref
        automatically matched to d1l1oa_
        complexed with dio
        1. region h:3-117 [149500] picpiclink
      5. 2pqa picpicxrefxref
        automatically matched to d1l1oa_
        1. region b:3-116 [149789] picpiclink
      6. 2pqa picpicxrefxref
        automatically matched to d1l1oa_
        1. region d:4-117 [149791] picpiclink
      7. 1quq picpicxref
        1. chain b [25305] picpiclink
        2. chain d [25306] picpiclink
      8. 2z6k picpicxrefxref
        automatically matched to d1l1oa_
        1. region c:3-117 [154178] picpiclink
      9. 2z6k picpicxrefxref
        automatically matched to d1l1oa_
        1. region d:3-117 [154179] picpiclink
      10. 1l1o picpicxrefxref
        complexed with zn
        1. chain a [73478] picpiclink
        2. chain d [73481] picpiclink
  6. CDC13 ssDNA-binding domain [74948]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [74949] (2)
      1. 1s40 picpic
        1. chain a [98470] picpiclink
      2. 1kxl picpic
        1. chain a [73155] picpiclink
  7. Telomere end binding protein alpha subunit [50273]
    duplication: consists of three domains of this fold
    1. Oxytricha nova [TaxId: 200597] [50274] (18)
      1. 1jb7 picpicxref
        complexed with cl, na
        1. region a:36-204 [62836] picpiclink
        2. region a:205-328 [62837] picpiclink
        3. region a:329-495 [62838] picpiclink
      2. 2i0q picpicxref
        automatically matched to d1ph1a1
        complexed with cl, edo
        1. region a:35-204 [136956] picpiclink
      3. 2i0q picpicxref
        automatically matched to d1jb7a2
        complexed with cl, edo
        1. region a:205-328 [136957] picpiclink
      4. 2i0q picpicxref
        automatically matched to d1jb7a3
        complexed with cl, edo
        1. region a:329-495 [136958] picpiclink
      5. 1ph6 picpicxref
        complexed with na
        1. region a:35-204 [88095] picpiclink
        2. region a:205-328 [88096] picpiclink
        3. region a:329-495 [88097] picpiclink
      6. 1ph4 picpicxref
        complexed with cl, na; mutant
        1. region a:36-204 [88087] picpiclink
        2. region a:205-328 [88088] picpiclink
        3. region a:329-495 [88089] picpiclink
      7. 1ph3 picpicxref
        complexed with na
        1. region a:36-204 [88083] picpiclink
        2. region a:205-328 [88084] picpiclink
        3. region a:329-495 [88085] picpiclink
      8. 1ph8 picpicxref
        complexed with cl, na; mutant
        1. region a:36-204 [88103] picpiclink
        2. region a:205-328 [88104] picpiclink
        3. region a:329-495 [88105] picpiclink
      9. 1pa6 picpicxref
        complexed with cl, na; mutant
        1. region a:36-204 [88009] picpiclink
        2. region a:205-328 [88010] picpiclink
        3. region a:329-495 [88011] picpiclink
      10. 1ph9 picpicxref
        complexed with cl, na; mutant
        1. region a:36-204 [88107] picpiclink
        2. region a:205-328 [88108] picpiclink
        3. region a:329-495 [88109] picpiclink
      11. 1ph5 picpicxref
        complexed with 3dr, cl, na; mutant
        1. region a:36-204 [88091] picpiclink
        2. region a:205-328 [88092] picpiclink
        3. region a:329-494 [88093] picpiclink
      12. 1ph1 picpicxref
        1. region a:35-204 [88075] picpiclink
        2. region a:205-328 [88076] picpiclink
        3. region a:329-495 [88077] picpiclink
      13. 1kix picpic
        complexed with so4
        1. region a:36-204 [68634] picpiclink
        2. region a:205-318 [68635] picpiclink
        3. region a:329-495 [68636] picpiclink
      14. 1phj picpicxref
        complexed with 3dr; mutant
        1. region a:35-204 [88111] picpiclink
        2. region a:205-328 [88112] picpiclink
        3. region a:329-492 [88113] picpiclink
      15. 1otc picpicxref
        1. region a:37-204 [25307] picpiclink
        2. region a:205-328 [25308] picpiclink
        3. region a:329-495 [25309] picpiclink
      16. 1ph2 picpicxref
        complexed with cl, na
        1. region a:36-204 [88079] picpiclink
        2. region a:205-328 [88080] picpiclink
        3. region a:329-494 [88081] picpiclink
      17. 1k8g picpic
        two-domain fragment
        complexed with so4
        1. region a:36-204 [68295] picpiclink
        2. region a:205-315 [68296] picpiclink
        3. region b:36-204 [68297] picpiclink
        4. region b:205-316 [68298] picpiclink
        5. region c:36-204 [68299] picpiclink
        6. region c:205-316 [68300] picpiclink
      18. 1ph7 picpicxref
        complexed with cl, na; mutant
        1. region a:36-204 [88099] picpiclink
        2. region a:205-328 [88100] picpiclink
        3. region a:329-495 [88101] picpiclink
  8. Core domain of telomere end binding protein beta subunit [50275]
    1. Oxytricha nova [TaxId: 200597] [50276] (14)
      1. 1jb7 picpicxref
        complexed with cl, na
        1. chain b [62839] picpiclink
      2. 2i0q picpicxrefxrefxref
        automatically matched to d1ph1b_
        complexed with cl, edo
        1. region b:9-224 [136959] picpiclink
      3. 1ph6 picpicxref
        complexed with na
        1. chain b [88098] picpiclink
      4. 1ph4 picpicxref
        complexed with cl, na; mutant
        1. chain b [88090] picpiclink
      5. 1ph3 picpicxref
        complexed with na
        1. chain b [88086] picpiclink
      6. 1ph8 picpicxref
        complexed with cl, na; mutant
        1. chain b [88106] picpiclink
      7. 1pa6 picpicxref
        complexed with cl, na; mutant
        1. chain b [88012] picpiclink
      8. 1ph9 picpicxref
        complexed with cl, na; mutant
        1. chain b [88110] picpiclink
      9. 1ph5 picpicxref
        complexed with 3dr, cl, na; mutant
        1. chain b [88094] picpiclink
      10. 1ph1 picpicxref
        1. chain b [88078] picpiclink
      11. 1phj picpicxref
        complexed with 3dr; mutant
        1. chain b [88114] picpiclink
      12. 1otc picpicxref
        1. chain b [25310] picpiclink
      13. 1ph2 picpicxref
        complexed with cl, na
        1. chain b [88082] picpiclink
      14. 1ph7 picpicxref
        complexed with cl, na; mutant
        1. chain b [88102] picpiclink
  9. Protection of telomeres protein 1, Pot1 [101761]
    1. Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896] [101762] (2)
      1. 1qzg picpic
        complexed with t
        1. chain a [96643] picpiclink
        2. chain b [96644] picpiclink
      2. 1qzh picpic
        1. chain a [96645] picpiclink
        2. chain b [96646] picpiclink
        3. chain c [96647] picpiclink
        4. chain d [96648] picpiclink
        5. chain e [96649] picpiclink
        6. chain f [96650] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [117190] (1)
      SQ Q9NUX5 6-299
      1. 1xjv picpic
        1. region a:6-145 [115396] picpiclink
        2. region a:149-299 [115397] picpiclink
  10. OB-fold domains of BRCA2 [82099]
    duplication: tandem repeat of three OB-fold domains
    1. Mouse (Mus musculus) [TaxId: 10090] [82100] (2)
      1. 1miu picpicxrefxref
        complexed with hg
        1. region a:2590-2722 [79155] picpiclink
        2. region a:2723-2751,a:2888-2970 [79156] picpiclink
        3. region a:2971-3103 [79157] picpiclink
      2. 1mje picpicxrefxref
        complex with ssDNA
        1. region a:2590-2722 [79195] picpiclink
        2. region a:2723-2751,a:2888-2970 [79196] picpiclink
        3. region a:2971-3110 [79197] picpiclink
    2. Rat (Rattus norvegicus) [TaxId: 10116] [82101] (1)
      1. 1iyj picpicxrefxref
        1. region b:2599-2731 [76950] picpiclink
        2. region b:2732-2760,b:2898-2979 [76951] picpiclink
        3. region b:2980-3117 [76952] picpiclink
        4. region d:2599-2731 [76955] picpiclink
        5. region d:2732-2760,d:2898-2979 [76956] picpiclink
        6. region d:2980-3117 [76957] picpiclink
  11. Primosomal replication protein N, PriB [117191]
    1. Escherichia coli [TaxId: 562] [117192] (4)
      SQ P07013
      1. 1v1q picpic
        complexed with cys; mutant
        1. chain a [113490] picpiclink
        2. chain b [113491] picpiclink
      2. 1txy picpic
        1. chain a [112791] picpiclink
        2. chain b [112792] picpiclink
      3. 2ccz picpic
        automatically matched to d1v1qb_
        mutant
        1. region a:-5-105 [130260] picpiclink
      4. 2ccz picpic
        automatically matched to d1v1qb_
        mutant
        1. region b:-4-105 [130261] picpiclink
  12. Hypothetical protein At4g28440 (F20O9.120) [117193]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117194] (1)
      SQ O49453 14-145
      1. 1wjj picpic
        Structural genomics target
        1. chain a [114699] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk