Structural Classification of Proteins

Fold: OB-fold

: barrel, closed or partly opened n=5, S=10 or S=8; greek-key

Lineage:

Root: scop
Class: All beta proteins [48724]
Fold: OB-fold [50198]
barrel, closed or partly opened n=5, S=10 or S=8; greek-key

Superfamilies:

Staphylococcal nuclease [50199] (1)
uperfamily
1. Staphylococcal nuclease [50200] (1)
  barrel, closed; n=5, S=10
Bacterial enterotoxins [50203] (2)
uperfamily
1. Bacterial AB5 toxins, B-subunits [50204] (9)
2. Superantigen toxins, N-terminal domain [50219] (15)
TIMP-like [50242] (3)
uperfamily
1. Tissue inhibitor of metalloproteinases, TIMP [50243] (3)
  contains an irregular alpha+beta subdomain in the C-terminal extension
2. Netrin-like domain (NTR/C345C module) [89320] (2)
  Pfam 01759
3. The laminin-binding domain of agrin [63767] (1)
Heme chaperone CcmE [82093] (1)
uperfamily
1. Heme chaperone CcmE [82094] (2)
gp5 N-terminal domain-like [69255] (1)
uperfamily
1. gp4 N-terminal domain-like [69256] (2)
Hypothetical protein YgiW [101756] (1)
uperfamily
1. Hypothetical protein YgiW [101757] (1)
  Pfam 04076, Domain of unknown function DUF388
Nucleic acid-binding proteins [50249] (16)
uperfamily
1. Anticodon-binding domain [50250] (7)
  barrel, closed; n=5, S=10
2. RecG "wedge" domain [69259] (1)
3. DNA helicase RuvA subunit, N-terminal domain [50259] (3)
  barrel, closed; n=5, S=10
4. Single strand DNA-binding domain, SSB [50263] (17)
  barrel, closed; n=5, S=10
5. Myf domain [50277] (7)
6. Cold shock DNA-binding domain-like [50282] (56)
  barrel, closed; n=5, S=8
7. TRAM domain [101768] (3)
  Pfam 01938
8. Hypothetical protein MTH1 (MT0001), insert domain [74955] (1)
9. DNA ligase/mRNA capping enzyme postcatalytic domain [50307] (6)
10. Phage ssDNA-binding proteins [50315] (5)
  barrel, open; n*=5, S*=8; the members' structures vary greater that those from cellular organisms
11. DNA replication initiator (cdc21/cdc54) N-terminal domain [89332] (1)
12. RNA polymerase subunit RBP8 [50321] (1)
  duplication; contains tandem repeat of two incomplete OB-folds; forms a single barrel; n=8, S=10
13. RecO N-terminal domain-like [117204] (1)
  N-terminal part of Pfam 02565
14. TIP49 domain [141315] (1)
  N-terminal part of Pfam 06068; the RuvA-like OB-fold domain in RuvB-like eukaryotic proteins
15. SSO2064-like [159109] (1)
  Pfam 01796; DUF35; contains extra N-terminal zinc finger subdomain of the rubredoxin-like fold
16. RNB domain-like [159112] (3)
  Pfam 00773; RNase II catalytic domain; decorated OB-fold domain with extra C-terminal structures forming the active site
Inorganic pyrophosphatase [50324] (1)
uperfamily
1. Inorganic pyrophosphatase [50325] (6)
  barrel, closed; n=5, S=8
MOP-like [50331] (3)
uperfamily
1. Molybdate/tungstate binding protein MOP [50332] (2)
2. BiMOP, duplicated molybdate-binding domain [50335] (2)
  duplication: tandem repeat of two OB-fold domains with swapped C-terminal strands
3. ABC-transporter additional domain [50338] (5)
  probably stems out from the biMOP domain
CheW-like [50341] (1)
uperfamily
1. CheW-like [50342] (2)
  duplication: tandem repeat of two swapped domains, one with a canonical OB-fold topology and one with a circular permutation
TM0957-like [141318] (1)
extra N-terminal region and large insertion after strand 3 together form an alpha-helical subdomain
uperfamily
1. TM0957-like [141319] (1)
NfeD domain-like [141322] (1)
close structural similarity to some members of the Nucleic acid-binding OB-fold proteins, possibly related to this superfamily
uperfamily
1. NfeD domain-like [141323] (1)
  C-terminal part of Pfam 01957
BC4932-like [159121] (1)
1. BC4932-like [159122] (2)
  Pfam 06486; DUF1093
HupF/HypC-like [159127] (1)
contains extra C-terminal helix packed against the beta-barrel side
1. HupF/HypC-like [159128] (3)
  Pfam 01455
EutN/CcmL-like [159133] (1)
homohexameric unit
1. EutN/CcmL-like [159134] (3)
  Pfam 03319
HIN-2000 domain-like [159141] (1)
duplication: tandem repeat of two OB-fold domains
1. HIN-200/IF120x domain [159142] (1)
  Pfam 02760