Structural Classification of Proteins
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Family: I set domains

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: I set domains [49159]

Protein Domains:

  1. Vascular cell adhesion molecule-1 (VCAM-1) [49160]
    1. Human (Homo sapiens) [TaxId: 9606] [49161] (3)
      1. 1vca picpicxref
        D1
        1. region a:1-90 [21685] picpiclink
        2. region b:1-90 [21686] picpiclink
      2. 1vsc picpicxref
        D1
        mutant
        1. region a:1-90 [21687] picpiclink
        2. region b:1-90 [21688] picpiclink
      3. 1ij9 picpicxref
        D1
        1. region a:1-90 [62483] picpiclink
  2. Intercellular adhesion molecule-1, ICAM-1 [49162]
    1. Human (Homo sapiens) [TaxId: 9606] [49163] (10)
      1. 1iam picpicxref
        D1
        complexed with nag; mutant
        1. region a:1-82 [21689] picpiclink
      2. 2oz4 picpicxrefxref
        automatically matched to d1p53a2
        complexed with fuc, nag, so4, trs, zn
        1. region a:186-282 [149100] picpiclink
      3. 2oz4 picpicxrefxref
        automatically matched to d1p53a3
        complexed with fuc, nag, so4, trs, zn
        1. region a:367-450 [149101] picpiclink
      4. 1ic1 picpicxref
        D1
        complexed with nag
        1. region a:1-82 [21690] picpiclink
        2. region b:1-82 [21691] picpiclink
      5. 1mq8 picpicxrefxref
        D1
        complexed with mg, nag; mutant
        1. region a:1-82 [79406] picpiclink
        2. region c:1-82 [79409] picpiclink
      6. 1z7z picpicxrefxref
        automatically matched to d1d3la2
        complexed with nag, ndg; mutant
        1. region i:1-82 [124682] picpiclink
      7. 1z7z picpicxrefxref
        automatically matched to d1p53a2
        complexed with nag, ndg; mutant
        1. region i:188-282 [124683] picpiclink
      8. 1z7z picpicxrefxref
        automatically matched to d1p53a3
        complexed with nag, ndg; mutant
        1. region i:367-450 [124684] picpiclink
      9. 1d3l picpicxref
        D1
        1. region a:1-82 [21692] picpiclink
      10. 1p53 picpicxref
        D3 and D5
        complexed with nag
        1. region a:185-282 [94119] picpiclink
        2. region a:367-450 [94120] picpiclink
        3. region b:185-282 [94122] picpiclink
        4. region b:367-450 [94123] picpiclink
  3. Intercellular adhesion molecule-2, ICAM-2 [49164]
    1. Human (Homo sapiens) [TaxId: 9606] [49165] (1)
      1. 1zxq picpicxref
        D1
        complexed with nag
        1. region a:1-86 [21693] picpiclink
  4. Neural cell adhesion molecule (NCAM) [49166]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [49167] (4)
      Rat and mouse sequences are identical for the two N-terminal modules
      1. 1epf picpic
        modules 1 and 2
        complexed with ca
        1. region a:1-97 [21694] picpiclink
        2. region a:98-189 [21695] picpiclink
        3. region b:-1-97 [21696] picpiclink
        4. region b:98-189 [21697] picpiclink
        5. region c:0-97 [21698] picpiclink
        6. region c:98-189 [21699] picpiclink
        7. region d:-1-97 [21700] picpiclink
        8. region d:98-189 [21701] picpiclink
      2. 1qz1 picpic
        modules 1, 2 and 3
        1. region a:-1-97 [96609] picpiclink
        2. region a:98-189 [96610] picpiclink
        3. region a:190-289 [96611] picpiclink
      3. 3ncm picpic
        module 2
        mutant
        1. chain a [21702] picpiclink
      4. 2ncm picpic
        module 1; from mouse protein
        1. chain a [21703] picpiclink
    2. Chicken (Gallus gallus) [TaxId: 9031] [63664] (1)
      1. 1ie5 picpic
        module 3
        1. chain a [62312] picpiclink
  5. Mucosal addressin cell adhesion molecule-1 (MADCAM-1) [49168]
    1. Human (Homo sapiens) [TaxId: 9606] [49169] (2)
      1. 1gsm picpic
        1. region a:1-90 [65535] picpiclink
        2. region a:91-206 [65536] picpiclink
      2. 1bqs picpic
        complexed with nag
        1. region a:1-90 [21704] picpiclink
        2. region a:91-209 [21705] picpiclink
  6. Telokin [49170]
    1. Turkey (Meleagris gallopavo) [TaxId: 9103] [49171] (2)
      1. 1fhg picpic
        1. chain a [21706] picpiclink
      2. 1tlk picpic
        1. chain a [21707] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [141012] (1)
      SQ Q9UIT9 1238-1338
      1. 2cqv picpic
        1. region a:8-108 [130730] picpiclink
  7. Cardiac myosin binding protein C, different domains [89185]
    1. Human (Homo sapiens) [TaxId: 9606] [89186] (3)
      SQ Q14896 358-451, 641-770
      1. 1pd6 picpic
        1. chain a [104121] picpiclink
      2. 2avg picpic
        1. region a:1-110 [127379] picpiclink
      3. 1gxe picpic
        1. chain a [83372] picpiclink
  8. Titin [49172]
    1. Human (Homo sapiens), different modules [TaxId: 9606] [49173] (5)
      1. 1g1c picpic
        module I1
        1. chain a [65078] picpiclink
        2. chain b [65079] picpiclink
      2. 1tnn picpic
        module M5
        1. chain a [21711] picpiclink
      3. 1ncu picpic
        module M5
        1. chain a [21709] picpiclink
      4. 1tnm picpic
        module M5
        1. chain a [21710] picpiclink
      5. 1nct picpic
        module M5
        1. chain a [21708] picpiclink
  9. Twitchin [49174]
    1. Nematode (Caenorhabditis elegans) [TaxId: 6239] [49175] (3)
      different modules
      1. 1koa picpicxref
        1. region a:6265-6361 [21712] picpiclink
      2. 1wiu picpic
        1. chain a [21713] picpiclink
      3. 1wit picpic
        1. chain a [21714] picpiclink
    2. Human (Homo sapiens), Ig repeat 27 [TaxId: 9606] [49176] (2)
      1. 1tiu picpic
        1. chain a [21715] picpiclink
      2. 1tit picpic
        1. chain a [21716] picpiclink
  10. Type-1 interleukin-1 receptor [49177]
    duplication: tandem repeat of 3 domains
    1. Human (Homo sapiens) [TaxId: 9606] [49178] (3)
      1. 1ira picpicxref
        complexed with nag
        1. region y:1-101 [21717] picpiclink
        2. region y:102-204 [21718] picpiclink
        3. region y:205-311 [21719] picpiclink
      2. 1itb picpicxref
        1. region b:6-101 [21720] picpiclink
        2. region b:102-204 [21721] picpiclink
        3. region b:205-315 [21722] picpiclink
      3. 1g0y picpicxref
        1. region r:6-101 [21723] picpiclink
        2. region r:102-204 [21724] picpiclink
        3. region r:205-315 [21725] picpiclink
  11. Fibroblast growth factor receptor, FGFR [49179]
    1. Human (Homo sapiens), FGFR1 [TaxId: 9606] [49180] (7)
      1. 2fdb picpicxrefxref
        automatically matched to d1cvsc1
        1. region p:2153-2251 [133298] picpiclink
      2. 2fdb picpicxrefxref
        automatically matched to d1cvsc2
        1. region p:2252-2360 [133299] picpiclink
      3. 2fdb picpicxrefxref
        automatically matched to d1cvsc1
        1. region r:3153-3251 [133300] picpiclink
      4. 2fdb picpicxrefxref
        automatically matched to d1cvsc2
        1. region r:3252-3360 [133301] picpiclink
      5. 1cvs picpicxref
        1. region c:149-250 [21726] picpiclink
        2. region c:251-359 [21727] picpiclink
        3. region d:149-250 [21728] picpiclink
        4. region d:251-359 [21729] picpiclink
      6. 1fq9 picpicxref
        complexed with idu, sgn, uap; mutant
        1. region c:149-250 [21734] picpiclink
        2. region c:251-359 [21735] picpiclink
        3. region d:149-250 [21736] picpiclink
        4. region d:251-359 [21737] picpiclink
      7. 1evt picpicxref
        complexed with so4
        1. region c:147-250 [21730] picpiclink
        2. region c:251-359 [21731] picpiclink
        3. region d:147-250 [21732] picpiclink
        4. region d:251-359 [21733] picpiclink
    2. Human (Homo sapiens), FGFR2a [TaxId: 9606] [49181] (8)
      1. 3dar picpic
        automatically matched to d1djsa1
        1. region a:153-249 [157466] picpiclink
      2. 3dar picpic
        automatically matched to d1djsa1
        1. region b:153-249 [157467] picpiclink
      3. 1ev2 picpicxref
        complexed with so4; mutant
        1. region e:150-250 [21738] picpiclink
        2. region e:251-360 [21739] picpiclink
        3. region f:150-250 [21740] picpiclink
        4. region f:251-359 [21741] picpiclink
        5. region g:151-250 [21742] picpiclink
        6. region g:251-363 [21743] picpiclink
        7. region h:151-250 [21744] picpiclink
        8. region h:251-363 [21745] picpiclink
      4. 1iil picpicxref
        mutant
        1. region e:150-250 [62437] picpiclink
        2. region e:251-361 [62438] picpiclink
        3. region f:150-250 [62439] picpiclink
        4. region f:251-361 [62440] picpiclink
        5. region g:150-250 [62441] picpiclink
        6. region g:251-364 [62442] picpiclink
        7. region h:150-250 [62443] picpiclink
        8. region h:251-364 [62444] picpiclink
      5. 1djs picpicxref
        1. region a:147-250 [21746] picpiclink
        2. region a:251-362 [21747] picpiclink
      6. 1ii4 picpicxref
        mutant
        1. region e:150-250 [62404] picpiclink
        2. region e:251-361 [62405] picpiclink
        3. region f:150-250 [62406] picpiclink
        4. region f:251-361 [62407] picpiclink
        5. region g:150-250 [62408] picpiclink
        6. region g:251-361 [62409] picpiclink
        7. region h:150-250 [62410] picpiclink
        8. region h:251-361 [62411] picpiclink
      7. 1e0o picpicxref
        complexed with 2si, ni, sgn, so4
        1. region b:149-250 [21748] picpiclink
        2. region b:251-360 [21749] picpiclink
        3. region d:149-250 [21750] picpiclink
        4. region d:251-360 [21751] picpiclink
      8. 1wvz picpic
        automatically matched to d1djsa1
        1. region a:8-104 [121347] picpiclink
    3. Human (Homo sapiens), FGFR2b [TaxId: 9606] [81955] (1)
      1. 1nun picpicxref
        complexed with 15p, mse, so4
        1. region b:151-250 [80735] picpiclink
        2. region b:251-359 [80736] picpiclink
    4. Human (Homo sapiens), FGFR3c [TaxId: 9606] [101514] (1)
      1. 1ry7 picpicxref
        1. region b:150-248 [98092] picpiclink
        2. region b:249-362 [98093] picpiclink
  12. Hemolin [49182]
    Duplication: tandem repeat of 4 domains, known as L1 domains
    1. Moth (Hyalophora cecropia) [TaxId: 7123] [49183] (1)
      1. 1bih picpic
        complexed with po4
        1. region a:5-98 [21752] picpiclink
        2. region a:99-209 [21753] picpiclink
        3. region a:210-306 [21754] picpiclink
        4. region a:307-395 [21755] picpiclink
        5. region b:5-98 [21756] picpiclink
        6. region b:99-209 [21757] picpiclink
        7. region b:210-306 [21758] picpiclink
        8. region b:307-395 [21759] picpiclink
  13. Semaphorin 4d Ig-like domain [101515]
    1. Human (Homo sapiens) [TaxId: 9606] [101516] (1)
      1. 1olz picpicxrefxref
        1. region a:537-628 [93341] picpiclink
        2. region b:537-628 [93344] picpiclink
  14. Axonin-1 [49184]
    tandem repeat of 4 L1 domains
    1. Chicken (Gallus gallus) [TaxId: 9031] [49185] (1)
      1. 1cs6 picpic
        complexed with gol
        1. region a:7-103 [21760] picpiclink
        2. region a:104-208 [21761] picpiclink
        3. region a:209-299 [21762] picpiclink
        4. region a:300-388 [21763] picpiclink
  15. Perlecan Ig3 domain [69158]
    1. Mouse (Mus musculus) [TaxId: 10090] [69159] (1)
      1. 1gl4 picpicxrefxref
        complexed with epe, zn
        1. chain b [65288] picpiclink
  16. Junction adhesion molecule, JAM, C-terminal domain [49186]
    1. Mouse (Mus musculus) [TaxId: 10090] [49187] (1)
      1. 1f97 picpicxref
        complexed with mg
        1. region a:129-238 [21764] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [89187] (1)
      1. 1nbq picpicxref
        1. region a:130-233 [85533] picpiclink
        2. region b:130-233 [85535] picpiclink
  17. Biliary glycoprotein C (CD66a, CEACAM1A[1,4]), C-terminal domain [81956]
    1. Mouse (Mus musculus) [TaxId: 10090] [81957] (1)
      1. 1l6z picpicxref
        complexed with man, nag
        1. region a:108-203 [77771] picpiclink
  18. Second domain of the Flt-1 receptor [49188]
    1. Human (Homo sapiens) [TaxId: 9606] [49189] (5)
      1. 1flt picpicxref
        1. chain x [21765] picpiclink
        2. chain y [21766] picpiclink
      2. 1rv6 picpicxref
        complexed with b3p
        1. chain x [97914] picpiclink
        2. chain y [97915] picpiclink
      3. 1qty picpicxref
        complex with VEGF
        1. chain x [21767] picpiclink
        2. chain y [21768] picpiclink
        3. chain t [21769] picpiclink
        4. chain u [21770] picpiclink
      4. 1qsz picpic
        1. chain a [21772] picpiclink
      5. 1qsv picpic
        1. chain a [21771] picpiclink
  19. Tyrosine-protein kinase receptor tyro3, second domain [101517]
    1. Human (Homo sapiens) [TaxId: 9606] [101518] (1)
      1. 1rhf picpicxref
        complexed with act, epe, zn
        1. region a:98-182 [97470] picpiclink
        2. region b:98-182 [97472] picpiclink
  20. High affinity nerve growth factor receptor TrkA, different domains [49190]
    1. Human (Homo sapiens) [TaxId: 9606] [49191] (7)
      1. 1he7 picpic
        swapped N-terminal strand dimer; only one subunit is in the PDB entry
        complexed with gol
        1. chain a [60970] picpiclink
      2. 1www picpicxref
        1. chain x [21773] picpiclink
        2. chain y [21774] picpiclink
      3. 1wwa picpic
        swapped N-terminal strand dimer
        1. chain x [21775] picpiclink
        2. chain y [21776] picpiclink
      4. 2ifg picpicxrefxrefxrefxref
        1st Iset domain
        complexed with bma, man, nag, ndg
        1. region a:192-283 [137335] picpiclink
      5. 2ifg picpicxrefxrefxrefxref
        automatically matched to d1he7a_
        complexed with bma, man, nag, ndg
        1. region a:285-382 [137336] picpiclink
      6. 2ifg picpicxrefxrefxrefxref
        automatically matched to 2IFG A:192-283
        complexed with bma, man, nag, ndg
        1. region b:192-283 [137338] picpiclink
      7. 2ifg picpicxrefxrefxrefxref
        automatically matched to d1he7a_
        complexed with bma, man, nag, ndg
        1. region b:285-382 [137339] picpiclink
  21. Ligand binding domain of trkB receptor [49192]
    1. Human (Homo sapiens) [TaxId: 9606] [49193] (2)
      1. 1wwb picpic
        swapped N-terminal strand dimer
        1. chain x [21777] picpiclink
      2. 1hcf picpicxref
        complexed with so4
        1. chain x [65790] picpiclink
        2. chain y [65791] picpiclink
  22. NT3 binding domain of trkC receptor [49194]
    1. Human (Homo sapiens) [TaxId: 9606] [49195] (1)
      1. 1wwc picpic
        swapped N-terminal strand dimer
        mutant
        1. chain a [21778] picpiclink
  23. Fc gamma receptor ectodomain (CD32) [49196]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens), IIa [TaxId: 9606] [49197] (2)
      1. 1fcg picpic
        mutant
        1. region a:4-88 [21779] picpiclink
        2. region a:89-174 [21780] picpiclink
      2. 1h9v picpic
        1. region a:1-88 [60851] picpiclink
        2. region a:89-172 [60852] picpiclink
    2. Human (Homo sapiens), IIb [TaxId: 9606] [49198] (1)
      1. 2fcb picpic
        1. region a:6-90 [21781] picpiclink
        2. region a:91-178 [21782] picpiclink
    3. Human (Homo sapiens), III [TaxId: 9606] [49199] (5)
      SQ O75015 23-189
      1. 1fnl picpic
        complexed with hg
        1. region a:3-86 [21783] picpiclink
        2. region a:87-175 [21784] picpiclink
      2. 1e4j picpic
        1. region a:2-86 [21785] picpiclink
        2. region a:87-172 [21786] picpiclink
      3. 1t83 picpicxrefxref
        complexed with fuc, gal, hg2, man, nag
        1. region c:5-86 [106647] picpiclink
        2. region c:87-171 [106648] picpiclink
      4. 1t89 picpicxrefxref
        complexed with fuc, gal, man, nag
        1. region c:5-86 [106661] picpiclink
        2. region c:87-171 [106662] picpiclink
      5. 1e4k picpicxrefxref
        complexed with fuc, gal, man, nag
        1. region c:1-86 [21787] picpiclink
        2. region c:87-172 [21788] picpiclink
  24. IgE high affinity receptor alpha subunit [49200]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [49201] (7)
      SQ P12319 29-196
      1. 1f2q picpic
        complexed with man, nag
        1. region a:4-85 [21789] picpiclink
        2. region a:86-174 [21790] picpiclink
      2. 1rpq picpic
        complexed with cit, man, nag, so4
        1. region a:4-85 [105028] picpiclink
        2. region a:86-171 [105029] picpiclink
        3. region b:4-85 [105030] picpiclink
        4. region b:86-171 [105031] picpiclink
        5. region c:4-85 [105032] picpiclink
        6. region c:86-171 [105033] picpiclink
        7. region d:4-85 [105034] picpiclink
        8. region d:86-171 [105035] picpiclink
      3. 1j86 picpic
        complexed with fuc, man, nag
        1. region a:1-85 [62711] picpiclink
        2. region a:86-174 [62712] picpiclink
        3. region b:1-85 [62713] picpiclink
        4. region b:86-173 [62714] picpiclink
      4. 1j88 picpic
        complexed with man, nag
        1. region a:4-85 [62717] picpiclink
        2. region a:86-171 [62718] picpiclink
        3. region b:4-85 [62719] picpiclink
        4. region b:86-171 [62720] picpiclink
        5. region c:4-85 [62721] picpiclink
        6. region c:86-171 [62722] picpiclink
        7. region d:4-85 [62723] picpiclink
        8. region d:86-171 [62724] picpiclink
        9. region e:4-85 [62725] picpiclink
        10. region e:86-171 [62726] picpiclink
      5. 1f6a picpicxrefxref
        complexed with cps, fuc, man, nag, so4; mutant
        1. region a:1-85 [21791] picpiclink
        2. region a:86-173 [21792] picpiclink
      6. 1j87 picpic
        complexed with fuc, man, nag; mutant
        1. region a:1-85 [62715] picpiclink
        2. region a:86-171 [62716] picpiclink
      7. 1j89 picpic
        complexed with man, nag
        1. region a:4-85 [62727] picpiclink
        2. region a:86-171 [62728] picpiclink
        3. region b:4-85 [62729] picpiclink
        4. region b:86-171 [62730] picpiclink
        5. region c:4-85 [62731] picpiclink
        6. region c:86-171 [62732] picpiclink
        7. region d:4-85 [62733] picpiclink
        8. region d:86-171 [62734] picpiclink
        9. region e:4-85 [62735] picpiclink
        10. region e:86-171 [62736] picpiclink
  25. Ig alpha Fc receptor, FCARI (CD89) [89188]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [89189] (3)
      1. 1uct picpic
        1. region a:2-100 [88467] picpiclink
        2. region a:101-196 [88468] picpiclink
      2. 1ovz picpic
        complexed with nag, trs
        1. region a:6-100 [87473] picpiclink
        2. region a:101-198 [87474] picpiclink
        3. region b:2-100 [87475] picpiclink
        4. region b:101-193 [87476] picpiclink
      3. 1ow0 picpicxrefxref
        complexed with IgA1 Fc
        complexed with fuc, gal, man, nag, sia
        1. region c:6-100 [87481] picpiclink
        2. region c:101-195 [87482] picpiclink
        3. region d:6-100 [87483] picpiclink
        4. region d:101-195 [87484] picpiclink
  26. Killer cell inhibitory receptor [49202]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens), kir2dl3 [TaxId: 9606] [49203] (2)
      1. 1efx picpicxrefxrefxref
        1. region d:4-103 [21793] picpiclink
        2. region d:104-200 [21794] picpiclink
        3. region e:4-103 [21795] picpiclink
        4. region e:104-200 [21796] picpiclink
      2. 1b6u picpic
        1. region a:5-103 [21797] picpiclink
        2. region a:104-203 [21798] picpiclink
    2. Human (Homo sapiens), kir2ds3, CD158j [TaxId: 9606] [89190] (1)
      1. 1m4k picpic
        complexed with egl, so4
        1. region a:8-103 [84796] picpiclink
        2. region a:104-200 [84797] picpiclink
    3. Human (Homo sapiens), p58-cl42 kir [TaxId: 9606] [49204] (2)
      1. 1nkr picpic
        1. region a:6-101 [21799] picpiclink
        2. region a:102-200 [21800] picpiclink
      2. 1im9 picpicxrefxrefxref
        1. region d:6-101 [62585] picpiclink
        2. region d:102-200 [62586] picpiclink
    4. Human (Homo sapiens), 2dl2 [TaxId: 9606] [49205] (2)
      1. 2dli picpic
        1. region a:5-101 [21801] picpiclink
        2. region a:102-200 [21802] picpiclink
      2. 2dl2 picpic
        1. region a:4-101 [21803] picpiclink
        2. region a:102-200 [21804] picpiclink
  27. Ligand binding domain of lir-1 (ilt2) [49206]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [49207] (8)
      SQ Q8NHL6 25-218
      1. 1ugn picpic
        mutant
        1. region a:2-97 [107828] picpiclink
        2. region a:98-195 [107829] picpiclink
      2. 1g0x picpic
        1. region a:2-97 [21805] picpiclink
        2. region a:98-198 [21806] picpiclink
      3. 3d2u picpicxrefxref
        automatically matched to d1g0xa1
        complexed with bma, fuc, man, nag; mutant
        1. region d:4-97 [157256] picpiclink
      4. 3d2u picpicxrefxref
        automatically matched to d1g0xa2
        complexed with bma, fuc, man, nag; mutant
        1. region d:98-198 [157257] picpiclink
      5. 3d2u picpicxrefxref
        automatically matched to d1g0xa1
        complexed with bma, fuc, man, nag; mutant
        1. region h:4-97 [157259] picpiclink
      6. 3d2u picpicxrefxref
        automatically matched to d1g0xa2
        complexed with bma, fuc, man, nag; mutant
        1. region h:98-198 [157260] picpiclink
      7. 1ufu picpic
        1. region a:2-97 [107819] picpiclink
        2. region a:98-195 [107820] picpiclink
      8. 1p7q picpicxrefxrefxref
        1. region d:4-97 [94315] picpiclink
        2. region d:98-198 [94316] picpiclink
  28. Ligand binding domain of NK receptor NKp46 [101519]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [101520] (2)
      1. 1oll picpic
        complexed with edo
        1. region a:1-95 [93313] picpiclink
        2. region a:96-188 [93314] picpiclink
      2. 1p6f picpic
        1. region a:4-98 [94169] picpiclink
        2. region a:99-191 [94170] picpiclink
  29. The p40 domain of interleukin-12 (IL-12 beta chain), N-terminal domain [63665]
    1. Human (Homo sapiens) [TaxId: 9606] [63666] (7)
      1. 3d85 picpicxrefxref
        automatically matched to d1f42a1
        complexed with imd, mpd; mutant
        1. region d:1-87 [157439] picpiclink
      2. 3duh picpicxrefxrefxrefxref
        automatically matched to d1f42a1
        complexed with nag
        1. region a:1-87 [157882] picpiclink
      3. 3duh picpicxrefxrefxrefxref
        automatically matched to d1f42a1
        complexed with nag
        1. region b:1-87 [157885] picpiclink
      4. 1f42 picpicxref
        complexed with man, mnb, nag
        1. region a:1-87 [59636] picpiclink
      5. 1f45 picpicxrefxref
        complexed with man, nag; mutant
        1. region a:1-87 [59639] picpiclink
      6. 3d87 picpicxrefxrefxrefxref
        automatically matched to d1f42a1
        complexed with k, man, po4; mutant
        1. region b:1-87 [157442] picpiclink
      7. 3d87 picpicxrefxrefxrefxref
        automatically matched to d1f42a1
        complexed with k, man, po4; mutant
        1. region d:1-87 [157445] picpiclink
  30. Interleukin-6 receptor alpha chain, N-terminal domain [81958]
    1. Human (Homo sapiens) [TaxId: 9606] [81959] (1)
      1. 1n26 picpicxref
        complexed with cys, man, nag, so4
        1. region a:1-93 [79850] picpiclink
  31. CD3 gamma chain ectodomain fragment [69160]
    possibly an intermediate structure between the I set and FnIII domains
    1. Mouse (Mus musculus) [TaxId: 10090] [69161] (1)
      1. 1jbj picpicxref
        a single-chain construct with epsilon chain domain, includes part of the linker
        1. region a:101-186 [66482] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [110050] (1)
      SQ P09693 # CD3G_HUMAN T-cell surface glycoprotein CD3 gamma chain precursor
      1. 1sy6 picpicxrefxrefxrefxrefxref
        MQ P09693 P07766 # artificial chimera
        1. region a:1-81 [106111] picpiclink
  32. CD3 epsilon chain ectodomain fragment [69162]
    possibly an intermediate structure between the I set and FnIII domains
    1. Mouse (Mus musculus) [TaxId: 10090] [69163] (2)
      SQ P22646 22-100
      1. 1jbj picpicxref
        a single-chain construct with gamma chain domain, includes part of the linker
        1. region a:1-100 [66483] picpiclink
      2. 1xmw picpicxref
        MQ P22646 P18438 # artificial chimera
        1. region a:1-79 [115566] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [110051] (2)
      SQ P07766 33-123 ! SQ P07766 # CD3E_HUMAN T-cell surface glycoprotein CD3 epsilon chain precursor
      1. 1xiw picpicxrefxrefxref
        1. chain a [115367] picpiclink
        2. chain e [115371] picpiclink
      2. 1sy6 picpicxrefxrefxrefxrefxref
        MQ P09693 P07766 # artificial chimera
        1. region a:118-203 [106112] picpiclink
    3. Sheep (Ovis aries) [TaxId: 9940] [117040] (1)
      SQ P18438 22-88
      1. 1xmw picpicxref
        MQ P22646 P18438 # artificial chimera
        1. region a:113-178 [115567] picpiclink
  33. B and T lymphocyte attenuator, Btla [117041]
    1. Mouse (Mus musculus) [TaxId: 10090] [117042] (1)
      SQ Q7TSA3 40-143
      1. 1xau picpic
        complexed with cd
        1. chain a [115041] picpiclink
  34. CD3 delta chain ectodomain fragment [117043]
    1. Human (Homo sapiens) [TaxId: 9606] [117044] (1)
      SQ P04234 23-95
      1. 1xiw picpicxrefxrefxref
        1. chain b [115368] picpiclink
        2. chain f [115372] picpiclink
  35. Myosin-binding protein C, slow-type [141013]
    1. Human (Homo sapiens) [TaxId: 9606] [141014] (2)
      SQ Q00872 342-431! SQ Q00872 58-170
      1. 1x44 picpic
        3rd Iset domain
        1. region a:8-97 [121678] picpiclink
      2. 2dav picpic
        1st Iset domain
        1. region a:8-120 [131357] picpiclink
  36. Receptor-type tyrosine-protein phosphatase mu [141015]
    1. Human (Homo sapiens) [TaxId: 9606] [141016] (1)
      SQ P28827 184-279
      1. 2c9a picpicxref
        complexed with ful, man, na, nag, ndg
        1. region a:184-279 [130129] picpiclink
  37. Cervical EMMPRIN [158877]
    contains two Ig-domains in the N-terminal part
    1. Human (Homo sapiens) [TaxId: 9606] [158878] (8)
      SQ Q54A51 103-203! SQ Q54A51 23-102
      1. 3b5h picpic
        complexed with act
        1. region a:103-203 [154838] picpiclink
      2. 3b5h picpic
        complexed with act
        1. region a:23-102 [154839] picpiclink
      3. 3b5h picpic
        automatically matched to 3B5H A:103-203
        complexed with act
        1. region b:103-203 [154840] picpiclink
      4. 3b5h picpic
        automatically matched to 3B5H A:23-102
        complexed with act
        1. region b:23-102 [154841] picpiclink
      5. 3b5h picpic
        automatically matched to 3B5H A:103-203
        complexed with act
        1. region c:103-202 [154842] picpiclink
      6. 3b5h picpic
        automatically matched to 3B5H A:23-102
        complexed with act
        1. region c:23-102 [154843] picpiclink
      7. 3b5h picpic
        automatically matched to 3B5H A:103-203
        complexed with act
        1. region d:103-201 [154844] picpiclink
      8. 3b5h picpic
        automatically matched to 3B5H A:23-102
        complexed with act
        1. region d:23-102 [154845] picpiclink
  38. Ligand binding domain of lir-2 (ilt4) [158879]
    1. Human (Homo sapiens) [TaxId: 9606] [158880] (2)
      SQ Q8N423 120-218! SQ Q8N423 26-109
      1. 2dyp picpicxrefxrefxref
        mutant
        1. region d:3-96 [145108] picpiclink
      2. 2dyp picpicxrefxrefxref
        mutant
        1. region d:97-195 [145109] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk