Structural Classification of Proteins
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Family: I set domains

Lineage:

  1. Root: scop
  2. Class: All beta proteins [48724]
  3. Fold: Immunoglobulin-like beta-sandwich [48725]
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. Superfamily: Immunoglobulin [48726]
    link to SUPERFAMILY database - Superfamily
  5. Family: I set domains [49159]

Protein Domains:

  1. Vascular cell adhesion molecule-1 (VCAM-1) [49160]
    1. Human (Homo sapiens) [TaxId: 9606] [49161] (3) picpic
  2. Intercellular adhesion molecule-1, ICAM-1 [49162]
    1. Human (Homo sapiens) [TaxId: 9606] [49163] (10) picpic
  3. Intercellular adhesion molecule-2, ICAM-2 [49164]
    1. Human (Homo sapiens) [TaxId: 9606] [49165] (1) picpic
  4. Neural cell adhesion molecule (NCAM) [49166]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [49167] (4) picpic
      Rat and mouse sequences are identical for the two N-terminal modules
    2. Chicken (Gallus gallus) [TaxId: 9031] [63664] (1) picpic
  5. Mucosal addressin cell adhesion molecule-1 (MADCAM-1) [49168]
    1. Human (Homo sapiens) [TaxId: 9606] [49169] (2) picpic
  6. Telokin [49170]
    1. Turkey (Meleagris gallopavo) [TaxId: 9103] [49171] (2) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [141012] (1) picpic
      SQ Q9UIT9 1238-1338
  7. Cardiac myosin binding protein C, different domains [89185]
    1. Human (Homo sapiens) [TaxId: 9606] [89186] (3) picpic
      SQ Q14896 358-451, 641-770
  8. Titin [49172]
    1. Human (Homo sapiens), different modules [TaxId: 9606] [49173] (5) picpic
  9. Twitchin [49174]
    1. Nematode (Caenorhabditis elegans) [TaxId: 6239] [49175] (3) picpic
      different modules
    2. Human (Homo sapiens), Ig repeat 27 [TaxId: 9606] [49176] (2) picpic
  10. Type-1 interleukin-1 receptor [49177]
    duplication: tandem repeat of 3 domains
    1. Human (Homo sapiens) [TaxId: 9606] [49178] (3) picpic
  11. Fibroblast growth factor receptor, FGFR [49179]
    1. Human (Homo sapiens), FGFR1 [TaxId: 9606] [49180] (7) picpic
    2. Human (Homo sapiens), FGFR2a [TaxId: 9606] [49181] (8) picpic
    3. Human (Homo sapiens), FGFR2b [TaxId: 9606] [81955] (1) picpic
    4. Human (Homo sapiens), FGFR3c [TaxId: 9606] [101514] (1) picpic
  12. Hemolin [49182]
    Duplication: tandem repeat of 4 domains, known as L1 domains
    1. Moth (Hyalophora cecropia) [TaxId: 7123] [49183] (1) picpic
  13. Semaphorin 4d Ig-like domain [101515]
    1. Human (Homo sapiens) [TaxId: 9606] [101516] (1) picpic
  14. Axonin-1 [49184]
    tandem repeat of 4 L1 domains
    1. Chicken (Gallus gallus) [TaxId: 9031] [49185] (1) picpic
  15. Perlecan Ig3 domain [69158]
    1. Mouse (Mus musculus) [TaxId: 10090] [69159] (1) picpic
  16. Junction adhesion molecule, JAM, C-terminal domain [49186]
    1. Mouse (Mus musculus) [TaxId: 10090] [49187] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [89187] (1) picpic
  17. Biliary glycoprotein C (CD66a, CEACAM1A[1,4]), C-terminal domain [81956]
    1. Mouse (Mus musculus) [TaxId: 10090] [81957] (1) picpic
  18. Second domain of the Flt-1 receptor [49188]
    1. Human (Homo sapiens) [TaxId: 9606] [49189] (5) picpic
  19. Tyrosine-protein kinase receptor tyro3, second domain [101517]
    1. Human (Homo sapiens) [TaxId: 9606] [101518] (1) picpic
  20. High affinity nerve growth factor receptor TrkA, different domains [49190]
    1. Human (Homo sapiens) [TaxId: 9606] [49191] (7) picpic
  21. Ligand binding domain of trkB receptor [49192]
    1. Human (Homo sapiens) [TaxId: 9606] [49193] (2) picpic
  22. NT3 binding domain of trkC receptor [49194]
    1. Human (Homo sapiens) [TaxId: 9606] [49195] (1) picpic
  23. Fc gamma receptor ectodomain (CD32) [49196]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens), IIa [TaxId: 9606] [49197] (2) picpic
    2. Human (Homo sapiens), IIb [TaxId: 9606] [49198] (1) picpic
    3. Human (Homo sapiens), III [TaxId: 9606] [49199] (5) picpic
      SQ O75015 23-189
  24. IgE high affinity receptor alpha subunit [49200]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [49201] (7) picpic
      SQ P12319 29-196
  25. Ig alpha Fc receptor, FCARI (CD89) [89188]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [89189] (3) picpic
  26. Killer cell inhibitory receptor [49202]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens), kir2dl3 [TaxId: 9606] [49203] (2) picpic
    2. Human (Homo sapiens), kir2ds3, CD158j [TaxId: 9606] [89190] (1) picpic
    3. Human (Homo sapiens), p58-cl42 kir [TaxId: 9606] [49204] (2) picpic
    4. Human (Homo sapiens), 2dl2 [TaxId: 9606] [49205] (2) picpic
  27. Ligand binding domain of lir-1 (ilt2) [49206]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [49207] (8) picpic
      SQ Q8NHL6 25-218
  28. Ligand binding domain of NK receptor NKp46 [101519]
    possibly an intermediate structure between the I set and FnIII domains
    1. Human (Homo sapiens) [TaxId: 9606] [101520] (2) picpic
  29. The p40 domain of interleukin-12 (IL-12 beta chain), N-terminal domain [63665]
    1. Human (Homo sapiens) [TaxId: 9606] [63666] (7) picpic
  30. Interleukin-6 receptor alpha chain, N-terminal domain [81958]
    1. Human (Homo sapiens) [TaxId: 9606] [81959] (1) picpic
  31. CD3 gamma chain ectodomain fragment [69160]
    possibly an intermediate structure between the I set and FnIII domains
    1. Mouse (Mus musculus) [TaxId: 10090] [69161] (1) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [110050] (1) picpic
      SQ P09693 # CD3G_HUMAN T-cell surface glycoprotein CD3 gamma chain precursor
  32. CD3 epsilon chain ectodomain fragment [69162]
    possibly an intermediate structure between the I set and FnIII domains
    1. Mouse (Mus musculus) [TaxId: 10090] [69163] (2) picpic
      SQ P22646 22-100
    2. Human (Homo sapiens) [TaxId: 9606] [110051] (2) picpic
      SQ P07766 33-123 ! SQ P07766 # CD3E_HUMAN T-cell surface glycoprotein CD3 epsilon chain precursor
    3. Sheep (Ovis aries) [TaxId: 9940] [117040] (1) picpic
      SQ P18438 22-88
  33. B and T lymphocyte attenuator, Btla [117041]
    1. Mouse (Mus musculus) [TaxId: 10090] [117042] (1) picpic
      SQ Q7TSA3 40-143
  34. CD3 delta chain ectodomain fragment [117043]
    1. Human (Homo sapiens) [TaxId: 9606] [117044] (1) picpic
      SQ P04234 23-95
  35. Myosin-binding protein C, slow-type [141013]
    1. Human (Homo sapiens) [TaxId: 9606] [141014] (2) picpic
      SQ Q00872 342-431! SQ Q00872 58-170
  36. Receptor-type tyrosine-protein phosphatase mu [141015]
    1. Human (Homo sapiens) [TaxId: 9606] [141016] (1) picpic
      SQ P28827 184-279
  37. Cervical EMMPRIN [158877]
    contains two Ig-domains in the N-terminal part
    1. Human (Homo sapiens) [TaxId: 9606] [158878] (8) picpic
      SQ Q54A51 103-203! SQ Q54A51 23-102
  38. Ligand binding domain of lir-2 (ilt4) [158879]
    1. Human (Homo sapiens) [TaxId: 9606] [158880] (2) picpic
      SQ Q8N423 120-218! SQ Q8N423 26-109
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk