Structural Classification of Proteins
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Superfamily: HRDC-like

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: SAM domain-like [47768]
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
  4. Superfamily: HRDC-like [47819]
    link to SUPERFAMILY database - Superfamily

Families:

  1. HRDC domain from helicases [47820] (3)
    1. HRDC domain from RecQ helicase [47821]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [47822] (1)
        1. 1d8b picpic
          1. chain a [18094] picpiclink
      2. Escherichia coli [TaxId: 562] [140639] (3)
        SQ P15043 530-606
        1. 1wud picpic
          1. region a:530-606 [121283] picpiclink
        2. 1wud picpic
          automatically matched to 1WUD A:530-606
          1. region b:531-606 [121284] picpiclink
        3. 1wud picpic
          automatically matched to 1WUD A:530-606
          1. region d:531-606 [121285] picpiclink
    2. Werner syndrome ATP-dependent helicase, WRN [140640]
      1. Human (Homo sapiens) [TaxId: 9606] [140641] (3)
        SQ Q14191 1140-1239! SQ Q14191 1142-1235
        1. 2e1f picpic
          automatically matched to 2E1E A:1142-1235
          complexed with cl
          1. region a:1142-1235 [131964] picpiclink
        2. 2e1e picpic
          complexed with cl
          1. region a:1142-1235 [131963] picpiclink
        3. 2dgz picpic
          1. region a:1140-1239 [131516] picpiclink
  2. RNA polymerase II subunit RBP4 (RpoF) [69044] (3)
    1. RNA polymerase II subunit RBP4 (RpoF) [69045]
      includes the N-terminal heterodimerisation alpha-hairpin
      1. Archaeon Methanococcus jannaschii [TaxId: 2190] [69046] (1)
        1. 1go3 picpicxrefxref
          1. chain f [65407] picpiclink
          2. chain n [65409] picpiclink
      2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [116939] (1)
        SQ P20433 46-221
        1. 1y14 picpicxrefxref
          1. chain a [116322] picpiclink
          2. chain c [116325] picpiclink
      3. Human (Homo sapiens) [TaxId: 9606] [140642] (4)
        SQ O15514 14-142
        1. 2c35 picpicxrefxrefxrefxrefxrefxrefxrefxref
          1. region a:14-142 [129711] picpiclink
        2. 2c35 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to 2C35 A:14-142
          1. region c:14-142 [129714] picpiclink
        3. 2c35 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to 2C35 A:14-142
          1. region e:14-139 [129717] picpiclink
        4. 2c35 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to 2C35 A:14-142
          1. region g:14-139 [129720] picpiclink
  3. RNase D C-terminal domains [140643] (1)
    tandem repeat of two domains of this fold, the first domain belongs to Pfam 00570
    1. Ribonuclease D [140644]
      1. Escherichia coli [TaxId: 562] [140645] (2)
        SQ P09155 194-294! SQ P09155 295-375
        1. 1yt3 picpicxref
          complexed with so4, zn
          1. region a:194-294 [123992] picpiclink
        2. 1yt3 picpicxref
          complexed with so4, zn
          1. region a:295-375 [123993] picpiclink
  4. EXOSC10 HRDC domain-like [140646] (2)
    1. Exosome complex exonuclease RRP6 domain [140647]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [140648] (4)
        SQ Q12149 421-516
        1. 2hbk picpicxref
          automatically matched to 2HBJ A:421-516
          complexed with mn; mutant
          1. region a:421-516 [136313] picpiclink
        2. 2hbj picpicxref
          mutant
          1. region a:421-516 [136311] picpiclink
        3. 2hbl picpicxref
          automatically matched to 2HBJ A:421-516
          complexed with amp, mn, zn; mutant
          1. region a:421-516 [136315] picpiclink
        4. 2hbm picpicxref
          automatically matched to 2HBJ A:421-516
          complexed with mn, u, zn; mutant
          1. region a:421-516 [136317] picpiclink
    2. Exosome component 10, EXOSC10 [140649]
      1. Human (Homo sapiens) [TaxId: 9606] [140650] (1)
        SQ Q01780 483-595
        1. 2cpr picpic
          1. region a:483-595 [130705] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk