Structural Classification of Proteins
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Family: MarR-like transcriptional regulators

The N- and C-terminal helical extensions to the common fold form the dimer interface

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: DNA/RNA-binding 3-helical bundle [46688]
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. Superfamily: "Winged helix" DNA-binding domain [46785]
    contains a small beta-sheet (wing)
    link to SUPERFAMILY database - Superfamily
  5. Family: MarR-like transcriptional regulators [63379]
    The N- and C-terminal helical extensions to the common fold form the dimer interface

Protein Domains:

  1. Multiple antibiotic resistance repressor, MarR [68970]
    1. Escherichia coli [TaxId: 562] [68971] (1) picpic
  2. MexR repressor [81686]
    1. Pseudomonas aeruginosa [TaxId: 287] [81687] (1) picpic
  3. Transcriptional regulator SlyA [81688]
    1. Enterococcus faecalis [TaxId: 1351] [81689] (1) picpic
    2. Salmonella typhimurium [TaxId: 90371] [158271] (2) picpic
      SQ P40676 1-140
  4. Staphylococcal accessory regulator A homolog, SarR [63472]
    1. Staphylococcus aureus [TaxId: 1280] [63473] (1) picpic
  5. Staphylococcal accessory regulator A homolog, SarS [88977]
    duplication: tandem repeat of two SarR-like domains assembled together as in the SarR dimer
    1. Staphylococcus aureus [TaxId: 1280] [88978] (1) picpic
  6. Pleiotropic regulator of virulence genes, SarA [48292]
    closely related to SarR but adopts a different fold; possible experimental artifact?
    1. Staphylococcus aureus [TaxId: 1280] [48293] (5) picpic
  7. Putative transcriptional regulator YusO [101012]
    1. Bacillus subtilis [TaxId: 1423] [101013] (1) picpic
  8. Hypothetical protein PH1061 [101014]
    1. Archaeon Pyrococcus horikoshii [TaxId: 53953] [101015] (1) picpic
  9. Putative transcriptional regulator TM0816 [140241]
    1. Thermotoga maritima [TaxId: 2336] [140242] (2) picpic
      SQ Q9WZS3 1-140
  10. Probable transcriptional regulator PA3067 [140243]
    1. Pseudomonas aeruginosa [TaxId: 287] [140244] (4) picpic
      SQ Q9HZE1 2-146
  11. Probable transcriptional regulator PA4135 [140245]
    1. Pseudomonas aeruginosa [TaxId: 287] [140246] (1) picpic
      SQ Q9HWP6 5-140
  12. Organic hydroperoxide resistance transcriptional regulator OhrR [140247]
    1. Bacillus subtilis [TaxId: 1423] [140248] (7) picpic
      SQ O34777 8-144
  13. Transcriptional regulator PA3341 [140249]
    1. Pseudomonas aeruginosa [TaxId: 287] [140250] (1) picpic
      SQ Q9HYQ4 8-144
  14. Protease production regulatory protein Hpr [140251]
    1. Bacillus subtilis [TaxId: 1423] [140252] (4) picpic
      SQ P11065 6-167
  15. Transcriptional regulator TM0710 [140253]
    1. Thermotoga maritima [TaxId: 2336] [140254] (4) picpic
      SQ Q9WZG9 5-143
  16. Transcriptional regulator DR1159 [140255]
    1. Deinococcus radiodurans [TaxId: 1299] [140256] (2) picpic
      SQ Q9RV71 8-179
  17. Transcriptional regulator MgrA [158272]
    1. Staphylococcus aureus [TaxId: 1280] [158273] (1) picpic
      SQ Q7A1J9 6-141
  18. Ta1064 (RFK), N-terminal domain [158274]
    1. Thermoplasma acidophilum [TaxId: 2303] [158275] (1) picpic
      SQ Q9HJA6 5-89
  19. Transcriptional regulator OEOE1854 [158276]
    1. Oenococcus oeni [TaxId: 1247] [158277] (4) picpic
      SQ Q04CY6 3-137

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk