Structural Classification of Proteins
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Family: Homeodomain

Pfam 00046

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: DNA/RNA-binding 3-helical bundle [46688]
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. Superfamily: Homeodomain-like [46689]
    consists only of helices
    link to SUPERFAMILY database - Superfamily
  5. Family: Homeodomain [46690]
    Pfam 00046

Protein Domains:

  1. Engrailed Homeodomain [46691]
    1. Drosophila melanogaster [TaxId: 7227] [46692] (10) picpic
  2. Mating type protein A1 Homeodomain [46693]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [46694] (6) picpic
  3. mat alpha2 Homeodomain [46695]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [46696] (6) picpic
  4. Hepatocyte nuclear factor 1a (LFB1/HNF1) [46697]
    atypical Homeodomain with a large insertion into HTH motif
    1. Rat (Rattus rattus) [TaxId: 10117] [46698] (2) picpic
    2. Human (Homo sapiens) [TaxId: 9606] [81680] (1) picpic
  5. Oct-1 POU Homeodomain [46699]
    1. Human (Homo sapiens) [TaxId: 9606] [46700] (7) picpic
  6. Pit-1 POU homeodomain [46701]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [46702] (1) picpic
  7. Thyroid transcription factor 1 homeodomain [46703]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [46704] (1) picpic
  8. Oct-2 POU Homeodomain [46705]
    1. Human (Homo sapiens) [TaxId: 9606] [46706] (1) picpic
  9. Oct-3 POU Homeodomain [46707]
    1. Mouse (Mus musculus) [TaxId: 10090] [46708] (1) picpic
  10. Homeobox protein hox-b1 [46709]
    1. Human (Homo sapiens) [TaxId: 9606] [46710] (1) picpic
  11. Homeobox protein hox-a9 [100994]
    1. Mouse (Mus musculus) [TaxId: 10090] [100995] (1) picpic
  12. pbx1 [46711]
    1. Human (Homo sapiens) [TaxId: 9606] [46712] (2) picpic
    2. Mouse (Mus musculus) [TaxId: 10090] [46713] (2) picpic
  13. Insulin gene enhancer protein isl-1 [46714]
    1. Rat (Rattus norvegicus) [TaxId: 10116] [46715] (1) picpic
  14. Msx-1 homeodomain [63463]
    1. Mouse (Mus musculus) [TaxId: 10090] [63464] (1) picpic
  15. Antennapedia Homeodomain [46716]
    1. Drosophila melanogaster [TaxId: 7227] [46717] (5) picpic
  16. Ultrabithorax (ubx) homeodomain [46718]
    1. Drosophila melanogaster [TaxId: 7227] [46719] (1) picpic
  17. Extradenticle (exd) homeodomain [46720]
    1. Drosophila melanogaster [TaxId: 7227] [46721] (3) picpic
  18. Even-skipped homeodomain [63465]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [63466] (1) picpic
  19. Fushi Tarazu protein [46722]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [46723] (1) picpic
  20. VND/NK-2 protein [46724]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [46725] (4) picpic
  21. Paired protein [46726]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [46727] (1) picpic
  22. Homeo-prospero domain of Prospero protein [81681]
    single domain composed of a homeodomain-homology N-terminal region (1245-1295) and the prospero-specific C-terminal region (1296-1396) that forms a 4-helical bundle
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [81682] (2) picpic
  23. Homeodomain-only protein, Hop [109647]
    1. Mouse (Mus musculus) [TaxId: 10090] [109648] (2) picpic
      SQ Q8R1H0
  24. ZF-HD homeobox protein At5g65410 [116772]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [116773] (1) picpic
      SQ Q9FKP8 182-248
  25. ZF-HD homeobox protein At4g24660 [116774]
    1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [116775] (1) picpic
      SQ Q9SB61 148-215
  26. DNA-binding protein SATB2 [116776]
    1. Human (Homo sapiens) [TaxId: 9606] [116777] (1) picpic
      SQ Q9UPW6 615-672 # the structure of the 1st CUT domain (350-437) is also known: 1WIZ
  27. Homeobox-leucine zipper protein Homez [116778]
    1. Human (Homo sapiens) [TaxId: 9606] [116779] (1) picpic
      SQ Q8IX15 337-399
      Structural genomics target
  28. Hepatocyte nuclear factor 6 [116780]
    1. Mouse (Mus musculus) [TaxId: 10090] [116781] (1) picpic
      SQ O08755 291-437
  29. LAG1 longevity assurance homolog 5, LASS5 [140141]
    1. Mouse (Mus musculus) [TaxId: 10090] [140142] (1) picpic
      SQ Q9D6K9 77-135
  30. Paired box protein pax6 [140143]
    1. Human (Homo sapiens) [TaxId: 9606] [140144] (1) picpic
      SQ P26367 211-278
  31. Transcriptional adaptor 2-like, TADA2L, isoform b [140145]
    1. Human (Homo sapiens) [TaxId: 9606] [140146] (1) picpic
      SQ Q9BVJ0 72-118
  32. Lag1 longevity assurance homolog 6, LASS6 [140147]
    1. Mouse (Mus musculus) [TaxId: 10090] [140148] (1) picpic
      SQ Q8C172 76-127
  33. Homeobox protein prh [140149]
    1. Human (Homo sapiens) [TaxId: 9606] [140150] (1) picpic
      SQ Q03014 138-194
  34. Pituitary homeobox 2 [140151]
    1. Human (Homo sapiens) [TaxId: 9606] [140152] (1) picpic
      SQ Q99697 85-144
  35. Homeobox protein pknox1 [140153]
    1. Human (Homo sapiens) [TaxId: 9606] [140154] (1) picpic
      SQ P55347 257-318
  36. Homeotic bicoid protein [140155]
    1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [140156] (1) picpic
      SQ P09081 97-163
  37. Hypothetical protein 4930532d21rik [140157]
    1. Mouse (Mus musculus) [TaxId: 10090] [140158] (1) picpic
      SQ Q8C0V1 712-760
  38. Homeobox-containing protein 1, HMBOX1 (Flj21616) [140159]
    1. Human (Homo sapiens) [TaxId: 9606] [140160] (1) picpic
      SQ Q6NT76 268-350
  39. Homeobox protein hox-b13 [140161]
    1. Human (Homo sapiens) [TaxId: 9606] [140162] (1) picpic
      SQ Q92826 216-273
  40. Zinc fingers and homeoboxes protein 1, ZHX1 [158242]
    1. Human (Homo sapiens) [TaxId: 9606] [158243] (1) picpic
      SQ Q9UKY1 565-640
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk