Family: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Lineage:

1. Root: scop
2. Class: All alpha proteins [46456]
3. Fold: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47322]
   core: 4 helices; bundle; one loop crosses over one side of the bundle
4. Superfamily: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47323]
   uperfamily
5. Family: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases [47324]

Protein Domains:

1. Methionyl-tRNA synthetase (MetRS) [47325]
   this domain follows the Rossmann-fold catalytic domain of class I aaRS
   1. Thermus thermophilus [TaxId: 274] [47326] (4)
   2. Escherichia coli [TaxId: 562] [47327] (9)
   3. Pyrococcus abyssi [TaxId: 29292] [109792] (1)
      SQ Q9V011 1-606 # C-domain 616-722 is solved separately: 1MKH
2. Cysteinyl-tRNA synthetase (CysRS) [74709]
   contains extra C-terminal alpha+beta subdomain: [alpha(2)-beta(2)], ordered in the complex with tRNA
   1. Escherichia coli [TaxId: 562] [74710] (3)
      SQ P21888; extra C-terminal subdomain: 407-461
3. Isoleucyl-tRNA synthetase (IleRS) [47328]
   1. Thermus thermophilus [TaxId: 274] [47329] (3)
   2. Staphylococcus aureus [TaxId: 1280] [47330] (3)
      contains additional alpha+beta and Zn-binding domains in the C-terminal extension
4. Valyl-tRNA synthetase (ValRS) [47331]
   includes additional alpha+beta (sub)domain at the C-terminus
   1. Thermus thermophilus [TaxId: 274] [47332] (3)
5. Arginyl-tRNA synthetase (ArgRS) [47333]
   1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [47334] (3)
   2. Thermus thermophilus [TaxId: 274] [69007] (1)
6. Leucyl-tRNA synthetase (LeuRS) [81746]
   1. Thermus thermophilus [TaxId: 274] [81747] (3)

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk