Structural Classification of Proteins
home mail help root up expand collapse

Superfamily: Regulator of G-protein signaling, RGS

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Regulator of G-protein signaling, RGS [48096]
    multihelical; consists of two all-alpha subdomains
    contains a 4-helical bundle with left-handed twist and up-and-down topology
  4. Superfamily: Regulator of G-protein signaling, RGS [48097]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Regulator of G-protein signaling, RGS [48098] (9)
    1. Regulator of G-protein signaling 4, RGS4 [48099]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [48100] (3)
        1. 1agr picpicxrefxref
          complexed with alf, cit, gdp, mg
          1. chain e [18538] picpiclink
          2. chain h [18539] picpiclink
        2. 1ezy picpic
          1. chain a [18540] picpiclink
        3. 1ezt picpic
          1. chain a [18541] picpiclink
    2. RGS9, RGS domain [48101]
      1. Cow (Bos taurus) [TaxId: 9913] [48102] (3)
        1. 1fqi picpic
          1. chain a [18542] picpiclink
        2. 1fqj picpicxrefxrefxref
          complexed with alf, gdp, mg
          1. chain b [18543] picpiclink
          2. chain e [18544] picpiclink
        3. 1fqk picpicxrefxref
          complexed with alf, gdp, mg
          1. chain b [18545] picpiclink
          2. chain d [18546] picpiclink
    3. Galpha interacting protein, GaIP [48103]
      1. Human (Homo sapiens) [TaxId: 9606] [48104] (1)
        1. 1cmz picpic
          1. chain a [18547] picpiclink
    4. Axin RGS-homologous domain [48105]
      1. Human (Homo sapiens) [TaxId: 9606] [48106] (2)
        1. 1dk8 picpic
          complexed with dtt, gol, so4
          1. chain a [18548] picpiclink
        2. 1emu picpic
          Complex with a samp repeat from apc; chain B
          complexed with gol
          1. chain a [18549] picpiclink
    5. p115RhoGEF [63584]
      1. Human (Homo sapiens) [TaxId: 9606] [63585] (1)
        1. 1iap picpic
          N-terminal RGS domain
          1. chain a [62119] picpiclink
    6. Pdz-RhoGEF RGS-like domain [63586]
      contains extra helices in the C-terminal extension
      1. Human (Homo sapiens) [TaxId: 9606] [63587] (1)
        1. 1htj picpic
          mutant
          1. chain f [61254] picpiclink
    7. G-protein coupled receptor kinase 2, N-terminal domain [89090]
      1. Cow (Bos taurus) [TaxId: 9913] [89091] (6)
        1. 1omw picpicxrefxrefxrefxref
          complexed with cmt; mutant
          1. region a:29-185 [87086] picpiclink
        2. 2bcj picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1omwa1
          complexed with ace, alf, gdp, mg; mutant
          1. region a:29-185 [128286] picpiclink
        3. 1ym7 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1omwa1
          mutant
          1. region a:29-185 [123685] picpiclink
        4. 1ym7 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1omwa1
          mutant
          1. region b:29-185 [123688] picpiclink
        5. 1ym7 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1omwa1
          mutant
          1. region c:29-185 [123691] picpiclink
        6. 1ym7 picpicxrefxrefxrefxrefxrefxrefxrefxref
          automatically matched to d1omwa1
          mutant
          1. region d:29-185 [123694] picpiclink
    8. Regulator of G-protein signaling 18, RGS18 [140750]
      1. Human (Homo sapiens) [TaxId: 9606] [140751] (1)
        SQ Q9NS28 75-206
        1. 2jm5 picpic
          1. region a:3-134 [138355] picpiclink
    9. Regulator of G-protein signaling 16, RGS16 [158689]
      1. Human (Homo sapiens) [TaxId: 9606] [158690] (2)
        SQ O15492 65-184
        1. 2ik8 picpicxrefxrefxrefxref
          complexed with alf, gdp, mg, so4
          1. region b:65-180 [145528] picpiclink
        2. 2ik8 picpicxrefxrefxrefxref
          automatically matched to 2IK8 B:65-180
          complexed with alf, gdp, mg, so4
          1. region d:65-180 [145529] picpiclink
Enter search key:
MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk