Structural Classification of Proteins
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Family: DNA-binding N-terminal domain of transcription activators

includes a dimerisation, antiparallel coiled-coil subdomain

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Putative DNA-binding domain [46954]
    core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different
  4. Superfamily: Putative DNA-binding domain [46955]
    link to SUPERFAMILY database - Superfamily
  5. Family: DNA-binding N-terminal domain of transcription activators [46962]
    includes a dimerisation, antiparallel coiled-coil subdomain

Protein Domains:

  1. Transcription activator BmrR [46963]
    followed by long alpha-helical linker
    1. Bacillus subtilis [TaxId: 1423] [46964] (7)
      SQ P39075
      1. 1r8e picpicxref
        complexed with 119, gol, imd
        1. region a:3-120 [104843] picpiclink
      2. 3d6z picpicxref
        automatically matched to d1exia1
        complexed with gol, rhq; mutant
        1. region a:3-120 [157414] picpiclink
      3. 3d71 picpicxref
        automatically matched to d1exia1
        complexed with etf, flc, imd, pgo, zn; mutant
        1. region a:3-120 [157418] picpiclink
      4. 3d6y picpicxref
        automatically matched to d1exia1
        complexed with ber, gol; mutant
        1. region a:3-120 [157412] picpiclink
      5. 3d70 picpicxref
        automatically matched to d1exia1
        complexed with gol, imd; mutant
        1. region a:3-120 [157416] picpiclink
      6. 1exj picpicxref
        protein/DNA complex; complexed with 119, na, zn
        1. region a:3-120 [16309] picpiclink
      7. 1exi picpicxref
        protein/DNA complex; complexed with 118, zn
        1. region a:3-120 [16310] picpiclink
  2. Multidrug transporter activator MtaN [68976]
    1. Bacillus subtilis [TaxId: 1423] [68977] (2)
      SQ P71039 1-109
      1. 1r8d picpic
        complexed with so4; mutant
        1. chain a [104841] picpiclink
        2. chain b [104842] picpiclink
      2. 1jbg picpic
        1. chain a [66480] picpiclink
  3. Transcriptional regulator CueR [101073]
    copper efflux regulator
    1. Escherichia coli [TaxId: 562] [101074] (3)
      1. 1q06 picpic
        complexed with ag
        1. chain a [95493] picpiclink
        2. chain b [95494] picpiclink
      2. 1q05 picpic
        complexed with cu1
        1. chain a [95491] picpiclink
        2. chain b [95492] picpiclink
      3. 1q07 picpic
        complexed with au
        1. chain a [95495] picpiclink
        2. chain b [95496] picpiclink
  4. Transcriptional regulator ZntR [101075]
    Zn(II)-responsive regulator of ZntA
    1. Escherichia coli [TaxId: 562] [101076] (3)
      1. 1q08 picpic
        zinc-binding, dimerisation subdomain only
        complexed with mg, po4, zn
        1. chain a [95497] picpiclink
        2. chain b [95498] picpiclink
      2. 1q0a picpic
        zinc-binding, dimerisation subdomain only
        complexed with so4, zn
        1. chain a [95500] picpiclink
        2. chain b [95501] picpiclink
      3. 1q09 picpic
        zinc-binding, dimerisation subdomain only
        complexed with so4, zn
        1. chain a [95499] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk