Structural Classification of Proteins
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Superfamily: Putative DNA-binding domain

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Putative DNA-binding domain [46954]
    core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different
  4. Superfamily: Putative DNA-binding domain [46955]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Domains B1 and B5 of PheRS-beta, PheT [46956] (1)
    duplication: contains two such domains related by pseudo dyad
    1. Domains B1 and B5 of PheRS-beta, PheT [46957]
      1. Thermus thermophilus [TaxId: 274] [46958] (13)
        identical sequence to Thermus aquaticus, TaxId: 271
        1. 1jjc picpicxrefxrefxrefxrefxref
          complexed with fa5, mn, so4
          1. region b:1-38,b:152-190 [66759] picpiclink
          2. region b:400-474 [66760] picpiclink
        2. 2aly picpicxrefxrefxrefxrefxref
          automatically matched to d1b70b1
          complexed with mn, so4, ysa
          1. region b:1-38,b:152-190 [126988] picpiclink
        3. 2aly picpicxrefxrefxrefxrefxref
          automatically matched to d1b70b2
          complexed with mn, so4, ysa
          1. region b:400-474 [126989] picpiclink
        4. 1pys picpicxrefxrefxrefxrefxref
          complexed with mg
          1. region b:1-38,b:152-190 [16299] picpiclink
          2. region b:400-474 [16300] picpiclink
        5. 2amc picpicxrefxrefxrefxrefxref
          automatically matched to d1b70b1
          complexed with mg, so4, tyr
          1. region b:1-38,b:152-190 [127003] picpiclink
        6. 2amc picpicxrefxrefxrefxrefxref
          automatically matched to d1b70b2
          complexed with mg, so4, tyr
          1. region b:400-474 [127004] picpiclink
        7. 2akw picpicxrefxrefxrefxrefxref
          automatically matched to d1b70b1
          complexed with 200, mn, so4
          1. region b:1-38,b:152-190 [126938] picpiclink
        8. 2akw picpicxrefxrefxrefxrefxref
          automatically matched to d1b70b2
          complexed with 200, mn, so4
          1. region b:400-474 [126939] picpiclink
        9. 1b7y picpicxrefxrefxrefxrefxref
          1. region b:1-38,b:152-190 [16301] picpiclink
          2. region b:400-474 [16302] picpiclink
        10. 2iy5 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1b70b1
          complexed with fya, mg
          1. region b:1-38,b:152-190 [137794] picpiclink
        11. 2iy5 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1b70b2
          complexed with fya, mg
          1. region b:400-474 [137795] picpiclink
        12. 1b70 picpicxrefxrefxrefxrefxref
          1. region b:1-38,b:152-190 [16303] picpiclink
          2. region b:400-474 [16304] picpiclink
        13. 1eiy picpicxrefxrefxrefxrefxrefxref
          1. region b:1-38,b:152-190 [16305] picpiclink
          2. region b:400-474 [16306] picpiclink
  2. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46959] (1)
    1. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46960]
      1. Human (Homo sapiens) [TaxId: 9606] [46961] (2)
        1. 1xpa picpicxref
          complexed with zn
          1. region a:134-210 [16308] picpiclink
        2. 1d4u picpicxref
          complexed with zn
          1. region a:37-111 [16307] picpiclink
  3. Dachshund-homology domain [74693] (2)
    Pfam 02437
    1. Retinal determination protein Dachshund [74694]
      1. Human (Homo sapiens) [TaxId: 9606] [74695] (1)
        1. 1l8r picpic
          complexed with mse
          1. chain a [73700] picpiclink
          2. chain b [73701] picpiclink
    2. Ski oncogene [109742]
      1. Human (Homo sapiens) [TaxId: 9606] [109743] (1)
        SQ P12755 91-192
        1. 1sbx picpic
          1. chain a [105414] picpiclink
  4. DNA-binding N-terminal domain of transcription activators [46962] (4)
    includes a dimerisation, antiparallel coiled-coil subdomain
    1. Transcription activator BmrR [46963]
      followed by long alpha-helical linker
      1. Bacillus subtilis [TaxId: 1423] [46964] (7)
        SQ P39075
        1. 1r8e picpicxref
          complexed with 119, gol, imd
          1. region a:3-120 [104843] picpiclink
        2. 3d6z picpicxref
          automatically matched to d1exia1
          complexed with gol, rhq; mutant
          1. region a:3-120 [157414] picpiclink
        3. 3d71 picpicxref
          automatically matched to d1exia1
          complexed with etf, flc, imd, pgo, zn; mutant
          1. region a:3-120 [157418] picpiclink
        4. 3d6y picpicxref
          automatically matched to d1exia1
          complexed with ber, gol; mutant
          1. region a:3-120 [157412] picpiclink
        5. 3d70 picpicxref
          automatically matched to d1exia1
          complexed with gol, imd; mutant
          1. region a:3-120 [157416] picpiclink
        6. 1exj picpicxref
          protein/DNA complex; complexed with 119, na, zn
          1. region a:3-120 [16309] picpiclink
        7. 1exi picpicxref
          protein/DNA complex; complexed with 118, zn
          1. region a:3-120 [16310] picpiclink
    2. Multidrug transporter activator MtaN [68976]
      1. Bacillus subtilis [TaxId: 1423] [68977] (2)
        SQ P71039 1-109
        1. 1r8d picpic
          complexed with so4; mutant
          1. chain a [104841] picpiclink
          2. chain b [104842] picpiclink
        2. 1jbg picpic
          1. chain a [66480] picpiclink
    3. Transcriptional regulator CueR [101073]
      copper efflux regulator
      1. Escherichia coli [TaxId: 562] [101074] (3)
        1. 1q06 picpic
          complexed with ag
          1. chain a [95493] picpiclink
          2. chain b [95494] picpiclink
        2. 1q05 picpic
          complexed with cu1
          1. chain a [95491] picpiclink
          2. chain b [95492] picpiclink
        3. 1q07 picpic
          complexed with au
          1. chain a [95495] picpiclink
          2. chain b [95496] picpiclink
    4. Transcriptional regulator ZntR [101075]
      Zn(II)-responsive regulator of ZntA
      1. Escherichia coli [TaxId: 562] [101076] (3)
        1. 1q08 picpic
          zinc-binding, dimerisation subdomain only
          complexed with mg, po4, zn
          1. chain a [95497] picpiclink
          2. chain b [95498] picpiclink
        2. 1q0a picpic
          zinc-binding, dimerisation subdomain only
          complexed with so4, zn
          1. chain a [95500] picpiclink
          2. chain b [95501] picpiclink
        3. 1q09 picpic
          zinc-binding, dimerisation subdomain only
          complexed with so4, zn
          1. chain a [95499] picpiclink
  5. Terminase gpNU1 subunit domain [74696] (1)
    1. Terminase gpNU1 subunit domain [74697]
      1. Bacteriophage lambda [TaxId: 10710] [74698] (1)
        1. 1j9i picpic
          1. chain a [71619] picpiclink
          2. chain b [71620] picpiclink
  6. Excisionase-like [46891] (2)
    kinked C-terminal helix
    1. mu transposase, DNA-binding domain [46892]
      1. Bacteriophage mu [TaxId: 10677] [46893] (4)
        1. 1qpm picpic
          1. chain a [16230] picpiclink
        2. 1g4d picpic
          protein/DNA complex
          1. chain a [16227] picpiclink
        3. 1tns picpic
          1. chain a [16228] picpiclink
        4. 1tnt picpic
          1. chain a [16229] picpiclink
    2. Excisionase Xis [89004]
      1. Bacteriophage lambda [TaxId: 10710] [89005] (8)
        SQ P03699 1-55
        1. 1rh6 picpic
          mutant
          1. chain a [104935] picpiclink
          2. chain b [104936] picpiclink
        2. 2og0 picpic
          automatically matched to d1lx8a_
          mutant
          1. region a:1-51 [139059] picpiclink
        3. 2og0 picpic
          automatically matched to d1lx8a_
          mutant
          1. region b:1-52 [139060] picpiclink
        4. 2ief picpic
          automatically matched to d1lx8a_
          mutant
          1. region a:1-55 [137304] picpiclink
        5. 2ief picpic
          automatically matched to d1lx8a_
          mutant
          1. region b:1-54 [137305] picpiclink
        6. 2ief picpic
          automatically matched to d1lx8a_
          mutant
          1. region c:1-53 [137306] picpiclink
        7. 1pm6 picpic
          mutant
          1. chain a [94894] picpiclink
        8. 1lx8 picpic
          C-terminally truncated variant
          mutant
          1. chain a [84734] picpiclink
  7. N-terminal subdomain of bacterial translation initiation factor IF2 [89006] (1)
    1. N-terminal subdomain of bacterial translation initiation factor IF2 [89007]
      1. Escherichia coli [TaxId: 562] [89008] (1)
        1. 1nd9 picpic
          1. chain a [85575] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk