Structural Classification of Proteins
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Fold: Putative DNA-binding domain

core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different

Lineage:

  1. Root: scop
  2. Class: All alpha proteins [46456]
  3. Fold: Putative DNA-binding domain [46954]
    core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different

Superfamilies:

  1. Putative DNA-binding domain [46955] (7)
    link to SUPERFAMILY database - Superfamily
    1. Domains B1 and B5 of PheRS-beta, PheT [46956] (1)
      duplication: contains two such domains related by pseudo dyad
      1. Domains B1 and B5 of PheRS-beta, PheT [46957]
        1. Thermus thermophilus [TaxId: 274] [46958] (13)
          identical sequence to Thermus aquaticus, TaxId: 271
          1. 1jjc picpicxrefxrefxrefxrefxref
            complexed with fa5, mn, so4
            1. region b:1-38,b:152-190 [66759] picpiclink
            2. region b:400-474 [66760] picpiclink
          2. 2aly picpicxrefxrefxrefxrefxref
            automatically matched to d1b70b1
            complexed with mn, so4, ysa
            1. region b:1-38,b:152-190 [126988] picpiclink
          3. 2aly picpicxrefxrefxrefxrefxref
            automatically matched to d1b70b2
            complexed with mn, so4, ysa
            1. region b:400-474 [126989] picpiclink
          4. 1pys picpicxrefxrefxrefxrefxref
            complexed with mg
            1. region b:1-38,b:152-190 [16299] picpiclink
            2. region b:400-474 [16300] picpiclink
          5. 2amc picpicxrefxrefxrefxrefxref
            automatically matched to d1b70b1
            complexed with mg, so4, tyr
            1. region b:1-38,b:152-190 [127003] picpiclink
          6. 2amc picpicxrefxrefxrefxrefxref
            automatically matched to d1b70b2
            complexed with mg, so4, tyr
            1. region b:400-474 [127004] picpiclink
          7. 2akw picpicxrefxrefxrefxrefxref
            automatically matched to d1b70b1
            complexed with 200, mn, so4
            1. region b:1-38,b:152-190 [126938] picpiclink
          8. 2akw picpicxrefxrefxrefxrefxref
            automatically matched to d1b70b2
            complexed with 200, mn, so4
            1. region b:400-474 [126939] picpiclink
          9. 1b7y picpicxrefxrefxrefxrefxref
            1. region b:1-38,b:152-190 [16301] picpiclink
            2. region b:400-474 [16302] picpiclink
          10. 2iy5 picpicxrefxrefxrefxrefxrefxref
            automatically matched to d1b70b1
            complexed with fya, mg
            1. region b:1-38,b:152-190 [137794] picpiclink
          11. 2iy5 picpicxrefxrefxrefxrefxrefxref
            automatically matched to d1b70b2
            complexed with fya, mg
            1. region b:400-474 [137795] picpiclink
          12. 1b70 picpicxrefxrefxrefxrefxref
            1. region b:1-38,b:152-190 [16303] picpiclink
            2. region b:400-474 [16304] picpiclink
          13. 1eiy picpicxrefxrefxrefxrefxrefxref
            1. region b:1-38,b:152-190 [16305] picpiclink
            2. region b:400-474 [16306] picpiclink
    2. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46959] (1)
      1. DNA repair factor XPA DNA- and RPA-binding domain, C-terminal subdomain [46960]
        1. Human (Homo sapiens) [TaxId: 9606] [46961] (2)
          1. 1xpa picpicxref
            complexed with zn
            1. region a:134-210 [16308] picpiclink
          2. 1d4u picpicxref
            complexed with zn
            1. region a:37-111 [16307] picpiclink
    3. Dachshund-homology domain [74693] (2)
      Pfam 02437
      1. Retinal determination protein Dachshund [74694]
        1. Human (Homo sapiens) [TaxId: 9606] [74695] (1)
          1. 1l8r picpic
            complexed with mse
            1. chain a [73700] picpiclink
            2. chain b [73701] picpiclink
      2. Ski oncogene [109742]
        1. Human (Homo sapiens) [TaxId: 9606] [109743] (1)
          SQ P12755 91-192
          1. 1sbx picpic
            1. chain a [105414] picpiclink
    4. DNA-binding N-terminal domain of transcription activators [46962] (4)
      includes a dimerisation, antiparallel coiled-coil subdomain
      1. Transcription activator BmrR [46963]
        followed by long alpha-helical linker
        1. Bacillus subtilis [TaxId: 1423] [46964] (7)
          SQ P39075
          1. 1r8e picpicxref
            complexed with 119, gol, imd
            1. region a:3-120 [104843] picpiclink
          2. 3d6z picpicxref
            automatically matched to d1exia1
            complexed with gol, rhq; mutant
            1. region a:3-120 [157414] picpiclink
          3. 3d71 picpicxref
            automatically matched to d1exia1
            complexed with etf, flc, imd, pgo, zn; mutant
            1. region a:3-120 [157418] picpiclink
          4. 3d6y picpicxref
            automatically matched to d1exia1
            complexed with ber, gol; mutant
            1. region a:3-120 [157412] picpiclink
          5. 3d70 picpicxref
            automatically matched to d1exia1
            complexed with gol, imd; mutant
            1. region a:3-120 [157416] picpiclink
          6. 1exj picpicxref
            protein/DNA complex; complexed with 119, na, zn
            1. region a:3-120 [16309] picpiclink
          7. 1exi picpicxref
            protein/DNA complex; complexed with 118, zn
            1. region a:3-120 [16310] picpiclink
      2. Multidrug transporter activator MtaN [68976]
        1. Bacillus subtilis [TaxId: 1423] [68977] (2)
          SQ P71039 1-109
          1. 1r8d picpic
            complexed with so4; mutant
            1. chain a [104841] picpiclink
            2. chain b [104842] picpiclink
          2. 1jbg picpic
            1. chain a [66480] picpiclink
      3. Transcriptional regulator CueR [101073]
        copper efflux regulator
        1. Escherichia coli [TaxId: 562] [101074] (3)
          1. 1q06 picpic
            complexed with ag
            1. chain a [95493] picpiclink
            2. chain b [95494] picpiclink
          2. 1q05 picpic
            complexed with cu1
            1. chain a [95491] picpiclink
            2. chain b [95492] picpiclink
          3. 1q07 picpic
            complexed with au
            1. chain a [95495] picpiclink
            2. chain b [95496] picpiclink
      4. Transcriptional regulator ZntR [101075]
        Zn(II)-responsive regulator of ZntA
        1. Escherichia coli [TaxId: 562] [101076] (3)
          1. 1q08 picpic
            zinc-binding, dimerisation subdomain only
            complexed with mg, po4, zn
            1. chain a [95497] picpiclink
            2. chain b [95498] picpiclink
          2. 1q0a picpic
            zinc-binding, dimerisation subdomain only
            complexed with so4, zn
            1. chain a [95500] picpiclink
            2. chain b [95501] picpiclink
          3. 1q09 picpic
            zinc-binding, dimerisation subdomain only
            complexed with so4, zn
            1. chain a [95499] picpiclink
    5. Terminase gpNU1 subunit domain [74696] (1)
      1. Terminase gpNU1 subunit domain [74697]
        1. Bacteriophage lambda [TaxId: 10710] [74698] (1)
          1. 1j9i picpic
            1. chain a [71619] picpiclink
            2. chain b [71620] picpiclink
    6. Excisionase-like [46891] (2)
      kinked C-terminal helix
      1. mu transposase, DNA-binding domain [46892]
        1. Bacteriophage mu [TaxId: 10677] [46893] (4)
          1. 1qpm picpic
            1. chain a [16230] picpiclink
          2. 1g4d picpic
            protein/DNA complex
            1. chain a [16227] picpiclink
          3. 1tns picpic
            1. chain a [16228] picpiclink
          4. 1tnt picpic
            1. chain a [16229] picpiclink
      2. Excisionase Xis [89004]
        1. Bacteriophage lambda [TaxId: 10710] [89005] (8)
          SQ P03699 1-55
          1. 1rh6 picpic
            mutant
            1. chain a [104935] picpiclink
            2. chain b [104936] picpiclink
          2. 2og0 picpic
            automatically matched to d1lx8a_
            mutant
            1. region a:1-51 [139059] picpiclink
          3. 2og0 picpic
            automatically matched to d1lx8a_
            mutant
            1. region b:1-52 [139060] picpiclink
          4. 2ief picpic
            automatically matched to d1lx8a_
            mutant
            1. region a:1-55 [137304] picpiclink
          5. 2ief picpic
            automatically matched to d1lx8a_
            mutant
            1. region b:1-54 [137305] picpiclink
          6. 2ief picpic
            automatically matched to d1lx8a_
            mutant
            1. region c:1-53 [137306] picpiclink
          7. 1pm6 picpic
            mutant
            1. chain a [94894] picpiclink
          8. 1lx8 picpic
            C-terminally truncated variant
            mutant
            1. chain a [84734] picpiclink
    7. N-terminal subdomain of bacterial translation initiation factor IF2 [89006] (1)
      1. N-terminal subdomain of bacterial translation initiation factor IF2 [89007]
        1. Escherichia coli [TaxId: 562] [89008] (1)
          1. 1nd9 picpic
            1. chain a [85575] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk