Structural Classification of Proteins

Superfamily: Globin-like

: uperfamily

Lineage:

Root: scop
Class: All alpha proteins [46456]
Fold: Globin-like [46457]
core: 6 helices; folded leaf, partly opened
Superfamily: Globin-like [46458]
uperfamily

Families:

Truncated hemoglobin [46459] (6)
lack the first helix (A)
1. Protozoan/bacterial hemoglobin [46460]
  1. Ciliate (Paramecium caudatum) [TaxId: 5885] [46461] (2)
  2. Green alga (Chlamydomonas eugametos) [TaxId: 3054] [46462] (2)
    Globin li637
  3. Cyanobacteria (Synechocystis sp.), pcc 6803 [TaxId: 1143] [81667] (5)
    SQ P73925
  4. Mycobacterium tuberculosis, HbN [TaxId: 1773] [63437] (4)
    SQ Q10784
  5. Mycobacterium tuberculosis, HbO [TaxId: 1773] [88965] (1)
  6. Bacillus subtilis [TaxId: 1423] [116748] (1)
    SQ O31607 6-124 # YjbI
Nerve tissue mini-hemoglobin (neural globin) [74660] (1)
lack the first helix but otherwise is more similar to conventional globins than the truncated ones
1. Nerve tissue mini-hemoglobin (neural globin) [74661]
  1. Milky ribbon-worm (Cerebratulus lacteus) [TaxId: 6221] [74662] (2)
    SQ O76242
Globins [46463] (81)
Heme-binding protein
1. Hemoglobin I [46464]
  1. Ark clam (Scapharca inaequivalvis) [TaxId: 6561] [46465] (19)
  2. Clam (Lucina pectinata) [TaxId: 29163] [46466] (4)
2. Trematode hemoglobin/myoglobin [63438]
  1. Paramphistomum epiclitum [TaxId: 54403] [63439] (2)
3. Glycera globin [46467]
  1. Marine bloodworm (Glycera dibranchiata) [TaxId: 6350] [46468] (8)
4. Myoglobin [46469]
  1. Sperm whale (Physeter catodon) [TaxId: 9755] [46470] (181)
    SQ P02185
  2. Slug sea hare (Aplysia limacina) [TaxId: 6502] [46471] (7)
  3. Common seal (Phoca vitulina) [TaxId: 9720] [46472] (1)
  4. Pig (Sus scrofa) [TaxId: 9823] [46473] (17)
  5. Horse (Equus caballus) [TaxId: 9796] [46474] (45)
  6. Human (Homo sapiens) [TaxId: 9606] [46475] (1)
  7. Asian elephant (Elephas maximus) [TaxId: 9783] [46476] (1)
  8. Loggerhead sea turtle (Caretta caretta) [TaxId: 8467] [46477] (2)
  9. Yellowfin tuna (Thunnus albacares) [TaxId: 8236] [46478] (1)
5. Erythrocruorin [46479]
  1. Midge (Chironomus thummi thummi), fraction III [TaxId: 7154] [46480] (4)
6. Leghemoglobin [46481]
  1. Yellow lupin (Lupinus luteus) [TaxId: 3873] [46482] (17)
  2. Soybean (Glycine max), isoform A [TaxId: 3847] [46483] (2)
7. Non-symbiotic plant hemoglobin [46484]
  1. Rice (Oryza sativa) [TaxId: 4530] [46485] (1)
8. Hemoglobin, alpha-chain [46486]
  1. Human (Homo sapiens) [TaxId: 9606] [46487] (192)
    SQ P69905 P01922 P01934 P01935
  2. Human (Homo sapiens), zeta isoform [TaxId: 9606] [68937] (1)
  3. Horse (Equus caballus) [TaxId: 9796] [46488] (19)
  4. Deer (Odocoileus virginianus) [TaxId: 9874] [46489] (1)
  5. Cow (Bos taurus) [TaxId: 9913] [46490] (11)
  6. Pig (Sus scrofa) [TaxId: 9823] [46491] (2)
  7. Maned wolf (Chrysocyon brachyurus) [TaxId: 68728] [63440] (5)
  8. Chicken (Gallus gallus) [TaxId: 9031] [46492] (1)
  9. Bar-headed goose (Anser indicus) [TaxId: 8846] [46493] (3)
  10. Graylag goose (Anser anser) [TaxId: 8843] [68938] (1)
  11. Aldabra giant tortoise (Geochelone gigantea) [TaxId: 167804] [100976] (3)
    SQ P83134
  12. Trout (Oncorhynchus mykiss) [TaxId: 8022] [46494] (2)
  13. Emerald rockcod (Pagothenia bernacchii) [TaxId: 40690] [46495] (9)
  14. Cartilaginous fish akaei (Dasyatis akajei) [TaxId: 31902] [46496] (2)
  15. Antarctic fish (Trematomus newnesi) [TaxId: 35730] [46497] (5)
  16. Fish (Leiostomus xanthurus) [TaxId: 59837] [46498] (1)
  17. Houndshark (Mustelus griseus) [TaxId: 89020] [46499] (2)
  18. Bluefin tuna (Thunnus thynnus) [TaxId: 8237] [109623] (3)
    SQ Q8AYM0
  19. Yellow perch (Perca flavescens) [TaxId: 8167] [116749] (1)
    SQ P83270; 78% sequence identity
  20. Donkey (Equus asinus) [TaxId: 9793] [158217] (1)
    SQ P01959 1-141
    beta-chain sequences of donkey and horse hemoglobins are identical
9. Hemoglobin, beta-chain [46500]
  1. Human (Homo sapiens) [TaxId: 9606] [46501] (195)
    SQ P68871
  2. Human fetus (Homo sapiens), gamma-chain [TaxId: 9606] [46502] (4)
  3. Human (Homo sapiens), embryonic gower II [TaxId: 9606] [46503] (1)
  4. Horse (Equus caballus) [TaxId: 9796] [46504] (19)
  5. Donkey (Equus asinus) [TaxId: 9793] [158216] (1)
    beta-chain sequences of donkey and horse hemoglobins are identical
  6. Deer (Odocoileus virginianus) [TaxId: 9874] [46505] (1)
  7. Cow (Bos taurus) [TaxId: 9913] [46506] (11)
  8. Pig (Sus scrofa) [TaxId: 9823] [46507] (2)
  9. Maned wolf (Chrysocyon brachyurus) [TaxId: 68728] [63441] (1)
  10. Mouse (Mus musculus) [TaxId: 10090] [68939] (1)
  11. Chicken (Gallus gallus) [TaxId: 9031] [46508] (1)
  12. Bar-headed goose (Anser indicus) [TaxId: 8846] [46509] (3)
  13. Graylag goose (Anser anser) [TaxId: 8843] [68940] (1)
  14. Aldabra giant tortoise (Geochelone gigantea) [TaxId: 167804] [100977] (3)
    SQ P83133
  15. Trout (Oncorhynchus mykiss) [TaxId: 8022] [46510] (2)
  16. Emerald rockcod (Pagothenia bernacchii) [TaxId: 40690] [46511] (9)
  17. Cartilaginous fish akaei (Dasyatis akajei) [TaxId: 31902] [46512] (2)
  18. Antarctic fish (Trematomus newnesi) [TaxId: 35730] [46513] (5)
  19. Fish (Leiostomus xanthurus) [TaxId: 59837] [46514] (1)
  20. Houndshark (Mustelus griseus) [TaxId: 89020] [46515] (2)
  21. Bluefin tuna (Thunnus thynnus) [TaxId: 8237] [109624] (3)
    SQ Q8AYM1
  22. Human (Homo sapiens), delta-chain [TaxId: 9606] [116750] (2)
    SQ P02042
  23. Yellow perch (Perca flavescens) [TaxId: 8167] [116751] (7)
    SQ P83273; 86% sequence identity
  24. Canis lupus familiaris [TaxId: 9615] [158218] (2)
10. Chimeric hemoglobin beta-alpha [46516]
  1. Synthetic, based on Homo sapiens sequence [46517] (1)
11. Hagfish hemoglobin [68941]
  1. Inshore hagfish (Eptatretus burgeri) [TaxId: 7764] [68942] (2)
12. Lamprey globin [46518]
  1. Sea lamprey (Petromyzon marinus) [TaxId: 7757] [46519] (4)
  2. Lamprey (Lampetra fluviatilis) [TaxId: 7748] [88966] (1)
13. Ascaris hemoglobin, domain 1 [46520]
  1. Pig roundworm (Ascaris suum) [TaxId: 6253] [46521] (1)
14. Hemoglobin [46522]
  1. Innkeeper worm (Urechis caupo) [TaxId: 6431] [46523] (1)
15. Hemoglobin, different isoforms [46524]
  1. Caudina arenicola, also known as Molpadia arenicola [TaxId: 7698] [46525] (2)
16. Neuroglobin [100978]
  1. Human (Homo sapiens) [TaxId: 9606] [100979] (1)
  2. Mouse (Mus musculus) [TaxId: 10090] [109625] (3)
    SQ Q9ER97
17. Bacterial dimeric hemoglobin [46526]
  1. Vitreoscilla stercoraria [TaxId: 61] [46527] (4)
18. Flavohemoglobin, N-terminal domain [46528]
  1. Alcaligenes eutrophus [TaxId: 106590] [46529] (1)
  2. Escherichia coli [TaxId: 562] [74663] (1)
19. Dehaloperoxidase [46530]
  1. Amphitrite ornata [TaxId: 129555] [46531] (4)
20. Heme-based aerotactic transducer HemAT, sensor domain [100980]
  1. Bacillus subtilis [TaxId: 1423] [100981] (2)
21. Cytoglobin [109626]
  1. Human (Homo sapiens) [TaxId: 9606] [109627] (6)
    SQ Q8WWM9 18-171
22. Hypothetical protein PA3967 [109628]
  1. Pseudomonas aeruginosa [TaxId: 287] [109629] (1)
    SQ Q9HX49
23. Extracellular dodecameric hemoglobin (erythrocruorin), subunit IV (globin A) [116752]
  1. Common earthworm (Lumbricus terrestris) [TaxId: 6398] [116753] (4)
    SQ P13579
24. Extracellular dodecameric hemoglobin (erythrocruorin), subunit II (globin B) [116754]
  1. Common earthworm (Lumbricus terrestris) [TaxId: 6398] [116755] (4)
    SQ P02218
25. Extracellular dodecameric hemoglobin (erythrocruorin), subunit III (globin C) [116756]
  1. Common earthworm (Lumbricus terrestris) [TaxId: 6398] [116757] (4)
    SQ P11069 20-168
26. Extracellular dodecameric hemoglobin (erythrocruorin), subunit D1 [116758]
  1. Common earthworm (Lumbricus terrestris) [TaxId: 6398] [116759] (4)
    SQ O61233 19-158
Phycocyanin-like phycobilisome proteins [46532] (26)
oligomers of two different types of globin-like subunits containing two extra helices at the N-terminus
binds a bilin chromophore
1. Phycocyanin alpha subunit [88933]
  1. Red alga (Cyanidium caldarium) [TaxId: 2771] [88934] (1)
  2. Red alga (Polysiphonia urceolata) [TaxId: 65404] [88936] (1)
  3. Cyanobacterium (Fremyella diplosiphon) [TaxId: 1197] [88937] (1)
  4. Synechococcus vulcanus [TaxId: 32053] [88938] (3)
  5. Synechococcus elongatus [TaxId: 32046] [88967] (1)
  6. Spirulina platensis [TaxId: 118562] [88939] (2)
  7. Spirulina sp. [TaxId: 1157] [158219] (12)
2. Phycocyanin beta subunit [88940]
  1. Red alga (Cyanidium caldarium) [TaxId: 2771] [88941] (1)
  2. Red alga (Polysiphonia urceolata) [TaxId: 65404] [88942] (1)
  3. Cyanobacterium (Fremyella diplosiphon) [TaxId: 1197] [88943] (1)
  4. Synechococcus vulcanus [TaxId: 32053] [88944] (3)
  5. Synechococcus elongatus [TaxId: 32046] [88968] (1)
  6. Spirulina platensis [TaxId: 118562] [88952] (2)
3. Allophycocyanin alpha subunit [88953]
  1. Spirulina platensis [TaxId: 118562] [88954] (1)
  2. Cyanobacterium (Mastigocladus laminosus) [TaxId: 83541] [88955] (1)
  3. Red algae (Porphyra yezoensis) [TaxId: 2788] [88956] (1)
4. Allophycocyanin beta subunit [88957]
  1. Spirulina platensis [TaxId: 118562] [88958] (1)
  2. Cyanobacterium (Mastigocladus laminosus) [TaxId: 83541] [88959] (1)
  3. Red algae (Porphyra yezoensis) [TaxId: 2788] [88960] (1)
5. Phycoerythrin alpha subunit [88961]
  1. Red alga (Polysiphonia urceolata) [TaxId: 65404] [88510] (1)
  2. Red alga (Griffithsia monilis) [TaxId: 42003] [88511] (1)
  3. Red algae (Gracilaria chilensis) [TaxId: 2775] [88512] (1)
6. Phycoerythrin beta subunit [88513]
  1. Red alga (Polysiphonia urceolata) [TaxId: 65404] [88514] (1)
  2. Red alga (Griffithsia monilis) [TaxId: 42003] [88515] (1)
  3. Red algae (Gracilaria chilensis) [TaxId: 2775] [88516] (1)
  4. Cryptophyte (Rhodomonas sp. CS24) [TaxId: 79257] [46544] (3)
    SQ P27198