Structural Classification of Proteins
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Family: Fibrinogen coiled-coil and central regions

in the central region two triple coiled-coils are stacked end-to-end and interlock with N-terminal tails

Lineage:

  1. Root: scop
  2. Class: Coiled coil proteins [57942]
    Not a true class
  3. Fold: Parallel coiled-coil [57943]
    this is not a true fold; includes oligomers of shorter identical helices
  4. Superfamily: Fibrinogen coiled-coil and central regions [58010]
    link to SUPERFAMILY database - Superfamily
  5. Family: Fibrinogen coiled-coil and central regions [58011]
    in the central region two triple coiled-coils are stacked end-to-end and interlock with N-terminal tails

Protein Domains:

  1. Fibrinogen alpha chain [88887]
    1. Chicken (Gallus gallus) [TaxId: 9031] [88888] (1)
      1. 1m1j picpicxrefxrefxrefxref
        complexed with ca, nag
        1. chain a [74369] picpiclink
        2. chain d [74374] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [88889] (32)
      SQ P02671 150-209
      1. 2oyh picpicxrefxref
        automatically matched to 2FFD A:126-190
        complexed with ca, fuc, nag; mutant
        1. region a:127-190 [139433] picpiclink
      2. 2oyh picpicxrefxref
        automatically matched to 2FFD A:126-190
        complexed with ca, fuc, nag; mutant
        1. region d:133-186 [139434] picpiclink
      3. 1re3 picpicxrefxrefxrefxref
        complexed with ca, nag; mutant
        1. chain a [104891] picpiclink
        2. chain d [104896] picpiclink
      4. 2hlo picpic
        automatically matched to d1fzaa_
        1. region a:126-192 [147309] picpiclink
      5. 1fzc picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, man, nag
        1. chain a [45590] picpiclink
        2. chain d [45593] picpiclink
      6. 1rf1 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, fuc, nag; mutant
        1. chain a [97348] picpiclink
        2. chain d [97353] picpiclink
      7. 2oyi picpicxrefxref
        automatically matched to 2FFD A:126-190
        complexed with ca, fuc, nag; mutant
        1. region a:126-190 [139435] picpiclink
      8. 2oyi picpicxrefxref
        automatically matched to 2FFD A:126-190
        complexed with ca, fuc, nag; mutant
        1. region d:133-188 [139436] picpiclink
      9. 1fzf picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. chain a [45596] picpiclink
        2. chain d [45599] picpiclink
      10. 1ltj picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, fuc, nag
        1. chain a [78198] picpiclink
        2. chain d [78203] picpiclink
      11. 1re4 picpicxrefxrefxrefxref
        complexed with ca, nag; mutant
        1. chain a [104901] picpiclink
        2. chain d [104906] picpiclink
      12. 1fzg picpicxrefxrefxrefxref
        complexed with ca, nag
        1. chain a [45602] picpiclink
        2. chain d [45605] picpiclink
      13. 1lt9 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. chain a [78188] picpiclink
        2. chain d [78193] picpiclink
      14. 2ffd picpic
        1. region a:126-190 [133379] picpiclink
      15. 2ffd picpic
        automatically matched to 2FFD A:126-190
        1. region d:133-189 [133380] picpiclink
      16. 1rf0 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag; mutant
        1. chain a [97338] picpiclink
        2. chain d [97343] picpiclink
      17. 1fzb picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. chain a [45608] picpiclink
        2. chain d [45611] picpiclink
      18. 2h43 picpic
        1. region a:126-195 [136067] picpiclink
      19. 2h43 picpic
        automatically matched to 2H43 A:126-195
        1. region d:126-195 [136068] picpiclink
      20. 1fze picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. chain a [45614] picpiclink
        2. chain d [45617] picpiclink
      21. 1n86 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, man, nag
        1. chain a [80277] picpiclink
        2. chain d [80282] picpiclink
      22. 1fza picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. chain a [45620] picpiclink
        2. chain d [45623] picpiclink
      23. 2hod picpic
        automatically matched to 2H43 A:126-195
        1. region a:126-192 [136635] picpiclink
      24. 2hod picpic
        automatically matched to 2H43 A:126-195
        1. region d:126-192 [136636] picpiclink
      25. 2hod picpic
        automatically matched to 2H43 A:126-195
        1. region g:126-192 [136637] picpiclink
      26. 2hod picpic
        automatically matched to 2H43 A:126-195
        1. region j:126-192 [136638] picpiclink
      27. 2hpc picpic
        automatically matched to 2H43 A:126-195
        1. region a:126-192 [136648] picpiclink
      28. 2hpc picpic
        automatically matched to 2H43 A:126-195
        1. region d:126-192 [136649] picpiclink
      29. 2hpc picpic
        automatically matched to 2H43 A:126-195
        1. region g:126-192 [136650] picpiclink
      30. 2hpc picpic
        automatically matched to 2H43 A:126-195
        1. region j:126-192 [136651] picpiclink
      31. 1qvh picpicxrefxrefxref
        central region only
        complexed with po4
        1. chain g [96421] picpiclink
        2. chain j [96424] picpiclink
      32. 1n8e picpicxrefxrefxrefxref
        coiled-coil region only
        1. chain a [80287] picpiclink
        2. chain d [80292] picpiclink
    3. Cow (Bos taurus) [TaxId: 9913] [88890] (2)
      1. 1jy2 picpicxrefxref
        central region only (e5 fragment)
        1. chain n [67440] picpiclink
        2. chain q [67443] picpiclink
      2. 1jy3 picpicxrefxref
        central region only (e5 fragment)
        1. chain n [67446] picpiclink
        2. chain q [67449] picpiclink
    4. Sea lamprey (Petromyzon marinus) [TaxId: 7757] [88891] (2)
      1. 1lwu picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, gal, man, nag, nh2
        1. chain a [74309] picpiclink
        2. chain d [74314] picpiclink
        3. chain g [74319] picpiclink
        4. chain j [74324] picpiclink
      2. 1n73 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. chain a [80214] picpiclink
        2. chain d [80219] picpiclink
  2. Fibrinogen beta chain [88892]
    1. Chicken (Gallus gallus) [TaxId: 9031] [88894] (1)
      1. 1m1j picpicxrefxrefxrefxref
        complexed with ca, nag
        1. region b:63-199 [74371] picpiclink
        2. region e:63-199 [74376] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [88895] (15)
      SQ P02675
      1. 1re3 picpicxrefxrefxrefxref
        complexed with ca, nag; mutant
        1. region b:165-199 [104893] picpiclink
        2. region e:165-199 [104898] picpiclink
      2. 1fzc picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, man, nag
        1. region b:151-199 [45591] picpiclink
        2. region e:151-199 [45594] picpiclink
      3. 1rf1 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, fuc, nag; mutant
        1. region b:161-199 [97350] picpiclink
        2. region e:165-199 [97355] picpiclink
      4. 1fzf picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region b:157-199 [45597] picpiclink
        2. region e:164-199 [45600] picpiclink
      5. 1ltj picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, fuc, nag
        1. region b:161-199 [78200] picpiclink
        2. region e:165-199 [78205] picpiclink
      6. 1re4 picpicxrefxrefxrefxref
        complexed with ca, nag; mutant
        1. region b:165-199 [104903] picpiclink
        2. region e:166-199 [104908] picpiclink
      7. 1fzg picpicxrefxrefxrefxref
        complexed with ca, nag
        1. region b:157-199 [45603] picpiclink
        2. region e:164-199 [45606] picpiclink
      8. 1lt9 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region b:161-199 [78190] picpiclink
        2. region e:165-199 [78195] picpiclink
      9. 1rf0 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag; mutant
        1. region b:154-199 [97340] picpiclink
        2. region e:160-199 [97345] picpiclink
      10. 1fzb picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region b:148-199 [45609] picpiclink
        2. region e:148-199 [45612] picpiclink
      11. 1fze picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region b:151-199 [45615] picpiclink
        2. region e:151-199 [45618] picpiclink
      12. 1n86 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, man, nag
        1. region b:151-199 [80279] picpiclink
        2. region e:151-199 [80284] picpiclink
      13. 1fza picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region b:148-199 [45621] picpiclink
        2. region e:148-199 [45624] picpiclink
      14. 1qvh picpicxrefxrefxref
        central region only
        complexed with po4
        1. chain h [96422] picpiclink
        2. chain k [96425] picpiclink
      15. 1n8e picpicxrefxrefxrefxref
        coiled-coil region only
        1. region b:151-199 [80289] picpiclink
        2. region e:151-199 [80294] picpiclink
    3. Cow (Bos taurus) [TaxId: 9913] [88896] (2)
      1. 1jy2 picpicxrefxref
        central region only (e5 fragment)
        1. chain o [67441] picpiclink
        2. chain r [67444] picpiclink
      2. 1jy3 picpicxrefxref
        central region only (e5 fragment)
        1. chain o [67447] picpiclink
        2. chain r [67450] picpiclink
    4. Sea lamprey (Petromyzon marinus) [TaxId: 7757] [88897] (2)
      1. 1lwu picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, gal, man, nag, nh2
        1. region b:163-218 [74311] picpiclink
        2. region e:163-218 [74316] picpiclink
        3. region h:163-218 [74321] picpiclink
        4. region k:163-218 [74326] picpiclink
      2. 1n73 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region b:163-218 [80216] picpiclink
        2. region e:163-218 [80221] picpiclink
  3. Fibrinogen gamma chain [88898]
    1. Chicken (Gallus gallus) [TaxId: 9031] [88899] (1)
      1. 1m1j picpicxrefxrefxrefxref
        complexed with ca, nag
        1. region c:4-141 [74373] picpiclink
        2. region f:5-141 [74378] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [88900] (18)
      SQ P02679
      1. 2oyh picpicxrefxrefxref
        complexed with ca, fuc, nag; mutant
        1. region c:96-141 [145739] picpiclink
      2. 1re3 picpicxrefxrefxrefxref
        complexed with ca, nag; mutant
        1. region c:106-141 [104895] picpiclink
        2. region f:106-141 [104900] picpiclink
      3. 1fzc picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, man, nag
        1. region c:97-141 [45592] picpiclink
        2. region f:97-141 [45595] picpiclink
      4. 1rf1 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, fuc, nag; mutant
        1. region c:96-141 [97352] picpiclink
        2. region f:103-141 [97357] picpiclink
      5. 3bvh picpic
        automatically matched to d1fzac2
        1. region c:102-141 [155663] picpiclink
      6. 2oyi picpicxrefxrefxref
        automatically matched to 2OYH C:96-141
        complexed with ca, fuc, nag; mutant
        1. region c:96-141 [145741] picpiclink
      7. 1fzf picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region c:102-141 [45598] picpiclink
        2. region f:109-141 [45601] picpiclink
      8. 1ltj picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, fuc, nag
        1. region c:96-141 [78202] picpiclink
        2. region f:110-141 [78207] picpiclink
      9. 1re4 picpicxrefxrefxrefxref
        complexed with ca, nag; mutant
        1. region c:106-141 [104905] picpiclink
        2. region f:106-141 [104910] picpiclink
      10. 1fzg picpicxrefxrefxrefxref
        complexed with ca, nag
        1. region c:102-141 [45604] picpiclink
        2. region f:109-141 [45607] picpiclink
      11. 1lt9 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region c:96-141 [78192] picpiclink
        2. region f:110-141 [78197] picpiclink
      12. 1rf0 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag; mutant
        1. region c:96-141 [97342] picpiclink
        2. region f:96-141 [97347] picpiclink
      13. 1fzb picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region c:88-141 [45610] picpiclink
        2. region f:88-141 [45613] picpiclink
      14. 1fze picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region c:92-141 [45616] picpiclink
        2. region f:92-141 [45619] picpiclink
      15. 1n86 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, man, nag
        1. region c:97-141 [80281] picpiclink
        2. region f:97-141 [80286] picpiclink
      16. 1fza picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region c:88-141 [45622] picpiclink
        2. region f:88-141 [45625] picpiclink
      17. 1qvh picpicxrefxrefxref
        central region only
        complexed with po4
        1. chain i [96423] picpiclink
        2. chain l [96426] picpiclink
      18. 1n8e picpicxrefxrefxrefxref
        coiled-coil region only
        1. region c:97-141 [80291] picpiclink
        2. region f:97-141 [80296] picpiclink
    3. Cow (Bos taurus) [TaxId: 9913] [88901] (2)
      1. 1jy2 picpicxrefxref
        central region only (e5 fragment)
        1. chain p [67442] picpiclink
        2. chain s [67445] picpiclink
      2. 1jy3 picpicxrefxref
        central region only (e5 fragment)
        1. chain p [67448] picpiclink
        2. chain s [67451] picpiclink
    4. Sea lamprey (Petromyzon marinus) [TaxId: 7757] [88902] (2)
      1. 1lwu picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, gal, man, nag, nh2
        1. region c:83-137 [74313] picpiclink
        2. region f:83-137 [74318] picpiclink
        3. region i:83-137 [74323] picpiclink
        4. region l:83-137 [74328] picpiclink
      2. 1n73 picpicxrefxrefxrefxref
        coiled-coil region only
        complexed with ca, nag
        1. region c:83-137 [80218] picpiclink
        2. region f:83-137 [80223] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk