Structural Classification of Proteins

Superfamily: SNARE fusion complex

: tetrameric parallel coiled coil
uperfamily

Lineage:

Root: scop
Class: Coiled coil proteins [57942]
Not a true class
Fold: Parallel coiled-coil [57943]
this is not a true fold; includes oligomers of shorter identical helices
Superfamily: SNARE fusion complex [58038]
tetrameric parallel coiled coil
uperfamily

Families:

SNARE fusion complex [58039] (18)
1. Synaptobrevin [88903]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [88904] (3)
    1. 1n7s
      complex with syntaxin and SNAP-25 fragments
      1. chain a [80271]
    2. 1kil
      complex with SNAP25, syntaxin and complexin fragments
      1. chain a [72518]
    3. 1sfc
      complex with syntaxin and SNAP-25 fragments
      1. chain a [45643]
      2. chain e [45647]
      3. chain i [45651]
  2. Longfin squid (Loligo pealei) [TaxId: 6621] [88905] (1)
    1. 1l4a
      complex with SNAP25, syntaxin and synaphin fragments
      1. chain a [73559]
  3. Saccharomyces cerevisiae [TaxId: 4932] [161253] (1)
    1. 3b5n
      automatically matched to d1sfca_
      1. region a:28-86 [154846]
2. Endobrevin [88906]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [88907] (1)
    1. 1gl2
      complex with syntaxin 7, VTI1B and syntaxin 8
      1. chain a [65278]
3. Syntaxin 1A [88908]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [88909] (6)
    SQ P32851 196-259
    a globular structure of a larger fragment containing this region is available; (1dn1), chain B
    1. 1n7s
      complex with synaptobrevin and SNAP-25 fragments
      1. chain b [80272]
    2. 1urq
      1. chain b [107995]
    3. 1jth
      complex with SNAP25 fragments
      1. chain b [67271]
      2. chain d [67273]
    4. 1hvv
      Self-association H3 region of syntaxin 1A
      1. chain a [45639]
      2. chain b [45640]
      3. chain c [45641]
      4. chain d [45642]
    5. 1kil
      complex with SNAP25, synaptobrevin and complexin fragments
      1. chain b [72519]
    6. 1sfc
      complex with synaptobrevin and SNAP-25 fragments
      1. chain b [45644]
      2. chain f [45648]
      3. chain j [45652]
  2. Longfin squid (Loligo pealei) [TaxId: 6621] [88910] (1)
    1. 1l4a
      complex with SNAP25, synaptobrevin and synaphin fragments
      1. chain b [73560]
  3. Saccharomyces cerevisiae [TaxId: 4932] [161254] (3)
    1. 3b5n
      automatically matched to d1sfcj_
      1. region b:189-254 [154847]
    2. 3b5n
      automatically matched to d1sfcj_
      1. region f:189-254 [154849]
    3. 3b5n
      automatically matched to d1sfcj_
      1. region j:191-254 [154850]
4. Syntaxin 7 [88911]
  complex with endobrevin, VTI1B and syntaxin 8
  1. Mouse (Mus musculus) [TaxId: 10090] [88912] (1)
    1. 1gl2
      1. chain b [65279]
5. Syntaxin 8 [88913]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [88914] (1)
    1. 1gl2
      complex with endobrevin, VTI1B and syntaxin 7
      1. chain d [65281]
6. Synaptosomal-associated protein SNAP-23 [90240]
  1. Human (Homo sapiens) [TaxId: 9606] [90241] (1)
    1. 1nhl
      N-terminal region (homotetramer)
      1. chain a [85722]
  2. Saccharomyces cerevisiae [TaxId: 4932] [161255] (1)
    1. 3b5n
      automatically matched to d1nhla_
      1. region c:443-496 [154848]
7. Synaptosomal-associated protein SNAP-25 [88915]
  provides up to two different helical regions to synaptic fusion complexes
  1. Rat (Rattus norvegicus) [TaxId: 10116] [88916] (4)
    SQ P13795 7-83; 142-204 # identical sequences to human species
    1. 1n7s
      complex with synaptobrevin and syntaxin fragments
      1. chain c [80273]
      2. chain d [80274]
    2. 1urq
      1. chain c [107996]
      2. chain d [107997]
    3. 1jth
      complex with syntaxin fragments
      1. chain a [67270]
      2. chain c [67272]
    4. 1sfc
      complex with synaptobrevin and syntaxin fragments
      1. chain c [45645]
      2. chain d [45646]
      3. chain g [45649]
      4. chain h [45650]
      5. chain k [45653]
      6. chain l [45654]
  2. Human (Homo sapiens) [TaxId: 9606] [88917] (2)
    SQ P60880 146-204 # identical sequence to rat species
    1. 1xtg
      complexed the catalytic domain of the botulinum neurotoxin
      complexed with cl, zn; mutant
      1. chain b [116021]
    2. 1kil
      complex with syntaxin, synaptobrevin and complexin fragments
      1. chain c [72520]
      2. chain d [72521]
  3. Longfin squid (Loligo pealei) [TaxId: 6621] [88918] (1)
    1. 1l4a
      complex with syntaxin, synaptobrevin and synaphin fragments
      1. chain c [73561]
      2. chain d [73562]
8. Vesicle transport v-SNARE protein VTI1b [88919]
  1. Mouse (Mus musculus) [TaxId: 10090] [88920] (1)
    1. 1gl2
      complex with endobrevin, syntaxin 7 and syntaxin 8
      1. chain c [65280]
9. Complexin [88921]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [88922] (1)
    1. 1kil
      complex with SNAP25, synaptobrevin and syntaxin fragments
      1. chain e [72522]
10. Synaphin [88923]
  1. Longfin squid (Loligo pealei) [TaxId: 6621] [88924] (1)
    1. 1l4a
      complex with SNAP25, synaptobrevin and syntaxin fragments
      1. chain e [73563]
11. M-tomosyn [111467]
  1. Rat (Rattus norvegicus) [TaxId: 10116] [111468] (1)
    SQ Q9Z152
    1. 1urq
      1. chain a [107994]