Structural Classification of Proteins
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Superfamily: Zinc beta-ribbon

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Rubredoxin-like [57769]
    metal(zinc or iron)-bound fold; sequence contains two CX(n)C motifs, in most cases n = 2
  4. Superfamily: Zinc beta-ribbon [57783]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Transcriptional factor domain [57784] (6)
    1. Transcriptional factor SII, C-terminal domain [57785]
      1. Human (Homo sapiens) [TaxId: 9606] [57786] (1) picpic
    2. Transcription initiation factor TFIIB, N-terminal domain [57789]
      1. Archaeon Pyrococcus furiosus [TaxId: 2261] [57790] (1) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [57791] (3) picpic
        SQ Q00403 2-59
    3. RBP9 subunit of RNA polymerase II [57787]
      contains two differently decorated domains of this fold
      1. Archaeon Thermococcus celer [TaxId: 2264] [57788] (1) picpic
      2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [64575] (41) picpic
        SQ P27999; part of multichain biological unit
    4. Transcription initiation factor TFIIE-alpha [118283]
      1. Human (Homo sapiens) [TaxId: 9606] [118284] (1) picpic
        SQ P29083 113-174
  2. DNA primase zinc finger [57792] (2)
    contains alpha-helices in the N- and C-terminal extensions (linkers?)
    1. Zinc-binding domain of DNA primase [57793]
      1. Bacillus stearothermophilus [TaxId: 1422] [57794] (1) picpic
    2. Zinc-binding domain of primase-helicase [90207]
      1. Bacteriophage T7 [TaxId: 10760] [90208] (1) picpic
  3. Prokaryotic DNA topoisomerase I, a C-terminal fragment [57795] (1)
    Duplication: contains tandem repeats of several domains with zinc-binding sites being lost in some of them
    1. Prokaryotic DNA topoisomerase I, a C-terminal fragment [57796]
      1. Escherichia coli [TaxId: 562] [57797] (1) picpic
  4. Putative zinc binding domain [118285] (1)
    Pfam 05129; DUF701
    1. Hypothetical UPF0222 protein MGC4549 [118286]
      1. Mouse (Mus musculus) [TaxId: 10090] [118287] (1) picpic
        SQ P60003
  5. PhnA zinc-binding domain [144191] (1)
    Pfam 08274
    1. Hypothetical protein PA0128, N-terminal domain [144192]
      1. Pseudomonas aeruginosa [TaxId: 287] [144193] (1) picpic
        SQ Q9I704 2-39
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk