Structural Classification of Proteins
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Family: Kringle modules

Lineage:

  1. Root: scop
  2. Class: Small proteins [56992]
    Usually dominated by metal ligand, heme, and/or disulfide bridges
  3. Fold: Kringle-like [57439]
    disulfide-rich fold; nearly all-beta
  4. Superfamily: Kringle-like [57440]
    link to SUPERFAMILY database - Superfamily
  5. Family: Kringle modules [57441]

Protein Domains:

  1. Plasminogen [63400]
    1. Human (Homo sapiens) [TaxId: 9606] [63401] (22)
      1. 1krn picpic
        kringle 4
        complexed with so4
        1. chain a [44629] picpiclink
      2. 5hpg picpic
        kringle 5
        1. chain a [44642] picpiclink
        2. chain b [44643] picpiclink
      3. 1pk4 picpic
        kringle 4
        complexed with so4
        1. chain a [44630] picpiclink
      4. 1ki0 picpic
        Angiostatin: the N-terminal fragment containing three kringles
        complexed with bcn; mutant
        1. region a:81-163 [72493] picpiclink
        2. region a:164-250 [72494] picpiclink
        3. region a:251-333 [72495] picpiclink
      5. 2doh picpic
        automatically matched to d1ki0a1
        complexed with dio; mutant
        1. region x:81-163 [131598] picpiclink
      6. 2doh picpic
        automatically matched to d1ki0a2
        complexed with dio; mutant
        1. region x:164-245 [131599] picpiclink
      7. 1pml picpic
        kringle 4
        complexed with cl
        1. chain a [44632] picpiclink
        2. chain b [44633] picpiclink
        3. chain c [44634] picpiclink
      8. 1tpk picpic
        kringle 2
        complexed with cl
        1. chain a [44637] picpiclink
        2. chain b [44638] picpiclink
        3. chain c [44639] picpiclink
      9. 1cea picpic
        kringle 1
        complexed with aca
        1. chain a [44644] picpiclink
        2. chain b [44645] picpiclink
      10. 2pk4 picpic
        kringle 4
        complexed with aca
        1. chain a [44631] picpiclink
      11. 1pkr picpic
        kringle 1
        complexed with cl
        1. chain a [44646] picpiclink
      12. 1ceb picpic
        kringle 1
        complexed with amh
        1. chain a [44647] picpiclink
        2. chain b [44648] picpiclink
      13. 1i5k picpic
        kringle 2; complexed to an internal peptide from a group A streptococcal surface protein
        mutant
        1. chain a [61789] picpiclink
        2. chain b [61790] picpiclink
      14. 1pmk picpic
        kringle 4
        1. chain a [44635] picpiclink
        2. chain b [44636] picpiclink
      15. 2doi picpic
        automatically matched to d1ki0a1
        mutant
        1. region a:81-163 [131600] picpiclink
      16. 2doi picpic
        automatically matched to d1ki0a2
        mutant
        1. region a:164-244 [131601] picpiclink
      17. 2doi picpic
        automatically matched to d1ki0a1
        mutant
        1. region x:81-163 [131602] picpiclink
      18. 2doi picpic
        automatically matched to d1ki0a2
        mutant
        1. region x:164-245 [131603] picpiclink
      19. 1b2i picpic
        kringle 2
        1. chain a [44640] picpiclink
      20. 1pk2 picpic
        kringle 2
        complexed with aha
        1. chain a [44641] picpiclink
      21. 1hpj picpic
        kringle 1
        1. chain a [44649] picpiclink
      22. 1hpk picpic
        kringle 1
        complexed with aca
        1. chain a [44650] picpiclink
  2. Prothrombin [57448]
    1. Cow (Bos taurus) [TaxId: 9913] [57449] (5)
      1. 1nl1 picpicxref
        complexed with ca, nag
        1. region a:66-147 [91949] picpiclink
      2. 1nl2 picpicxref
        complexed with ca, cl, lps, nag
        1. region a:66-146 [91951] picpiclink
      3. 2pf2 picpicxref
        complexed with ca
        1. region a:66-146 [44651] picpiclink
      4. 2spt picpicxref
        complexed with nag, sr
        1. region a:66-145 [44653] picpiclink
      5. 2pf1 picpicxref
        1. region a:66-156 [44652] picpiclink
  3. Meizothrombin [57450]
    1. Cow (Bos taurus) [TaxId: 9913] [57451] (2)
      1. 2hpp picpicxref
        complexed with ch2
        1. chain p [44654] picpiclink
      2. 1a0h picpicxref
        complexed with ch2, nag
        1. region a:164-270 [44655] picpiclink
        2. region d:164-270 [44656] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [57452] (1)
      1. 2hpq picpicxref
        complexed with ch2
        1. chain p [44657] picpiclink
  4. Urokinase-type plasminogen activator [57453]
    1. Human (Homo sapiens) [TaxId: 9606] [57454] (13)
      1. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with po4
        1. region a:50-132 [137111] picpiclink
      2. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with po4
        1. region b:50-132 [137113] picpiclink
      3. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with po4
        1. region c:50-132 [137115] picpiclink
      4. 2i9a picpicxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with po4
        1. region d:50-132 [137117] picpiclink
      5. 2fd6 picpicxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with edo, etx, fuc, nag, pg4, pge, so4
        1. region a:50-132 [133294] picpiclink
      6. 3bt2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urka2
        complexed with nag
        1. region a:50-132 [155541] picpiclink
      7. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with bma, nag, so4; mutant
        1. region a:50-132 [137119] picpiclink
      8. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with bma, nag, so4; mutant
        1. region b:50-132 [137121] picpiclink
      9. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with bma, nag, so4; mutant
        1. region c:50-132 [137123] picpiclink
      10. 2i9b picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1urk_2
        complexed with bma, nag, so4; mutant
        1. region d:50-132 [137125] picpiclink
      11. 3bt1 picpicxrefxrefxrefxrefxref
        automatically matched to d1urka2
        complexed with man, nag
        1. region a:50-132 [155535] picpiclink
      12. 1kdu picpic
        1. chain a [44658] picpiclink
      13. 1urk picpicxref
        complexed with fuc
        1. region a:50-135 [44659] picpiclink
  5. Apolipoprotein A [57455]
    1. Human (Homo sapiens), IV-10/M66 variant [TaxId: 9606] [57456] (3)
      1. 3kiv picpic
        complexed with aca
        1. chain a [44660] picpiclink
      2. 1kiv picpic
        1. chain a [44661] picpiclink
      3. 4kiv picpic
        mutant
        1. chain a [44662] picpiclink
    2. Human (Homo sapiens), IV-6 variant [TaxId: 9606] [75673] (1)
      1. 1jfn picpic
        1. chain a [71660] picpiclink
    3. Human (Homo sapiens), IV-7 variant [TaxId: 9606] [64559] (1)
      1. 1i71 picpic
        complexed with so4
        1. chain a [61864] picpiclink
  6. NK1 fragment of hepatocyte growth factor [57457]
    1. Human (Homo sapiens) [TaxId: 9606] [57458] (7)
      1. 2qj2 picpicxrefxref
        automatically matched to d1bhta2
        complexed with so4
        1. region a:127-209 [150818] picpiclink
      2. 2qj2 picpicxrefxref
        automatically matched to d1bhta2
        complexed with so4
        1. region b:1127-1209 [150820] picpiclink
      3. 1bht picpicxref
        complexed with epe, so4
        1. region a:127-210 [44663] picpiclink
        2. region b:427-509 [44664] picpiclink
      4. 1gmn picpicxref
        complexed with epe, ids, sgn; mutant
        1. region a:126-207 [65316] picpiclink
        2. region b:126-209 [65318] picpiclink
      5. 1gp9 picpicxref
        complexed with epe
        1. region a:126-208 [65443] picpiclink
        2. region b:126-208 [65445] picpiclink
        3. region c:126-208 [65447] picpiclink
        4. region d:126-208 [65449] picpiclink
      6. 1nk1 picpicxref
        mutant
        1. region a:126-209 [44665] picpiclink
        2. region b:126-209 [44666] picpiclink
      7. 1gmo picpicxref
        complexed with epe, ids, sgn, so4; mutant
        1. region a:126-208 [65320] picpiclink
        2. region b:126-208 [65322] picpiclink
        3. region c:126-208 [65324] picpiclink
        4. region d:126-208 [65326] picpiclink
        5. region e:126-209 [65328] picpiclink
        6. region f:126-209 [65330] picpiclink
        7. region g:126-208 [65332] picpiclink
        8. region h:126-208 [65334] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk