Protein: Insulin from Human (Homo sapiens) [TaxId: 9606]

SQ P01308

Lineage:

1. Root: scop
2. Class: Small proteins [56992]
   Usually dominated by metal ligand, heme, and/or disulfide bridges
3. Fold: Insulin-like [56993]
   nearly all-alpha
   can be classified as disulfide-rich
4. Superfamily: Insulin-like [56994]
   uperfamily
5. Family: Insulin-like [56995]
6. Protein: Insulin [56996]
7. Species: Human (Homo sapiens) [TaxId: 9606] [56998]
   SQ P01308

PDB Entry Domains:

1. 1mso
   complexed with zn
   1. chain b,a [85092]
   2. chain d,c [85093]
2. 1g7a
   complexed with acn, cl, cry, zn
   1. chain b,a [60322]
   2. chain d,c [60323]
   3. chain f,e [60324]
   4. chain h,g [60325]
3. 1g7b
   complexed with acn, cl, cry, zn
   1. chain b,a [60326]
   2. chain d,c [60327]
   3. chain f,e [60328]
   4. chain h,g [60329]
4. 1ben
   complexed with cl, hbd, zn
   1. chain b,a [43837]
   2. chain d,c [43838]
5. 1zeh
   complexed with cl, crs, zn; mutant
   1. chain b,a [43839]
   2. chain d,c [43840]
6. 1zeg
   complexed with cl, iph, zn; mutant
   1. chain b,a [43841]
   2. chain d,c [43842]
7. 1guj
   structure at pH 2: the conditions promoting insulin fibre formation
   complexed with so4
   1. chain b,a [70582]
   2. chain d,c [70583]
8. 1ev3
   complexed with cl, crs, zn
   1. chain b,a [43845]
   2. chain d,c [43846]
9. 1trz
   complexed with cl, na, zn
   1. chain b,a [43843]
   2. chain d,c [43844]
10. 1xda
    complexed with cl, iph, myr, zn
    1. chain b,a [43847]
    2. chain d,c [43848]
    3. chain f,e [43849]
    4. chain h,g [43850]
11. 1evr
    complexed with cl, na, rco, zn
    1. chain b,a [43851]
    2. chain d,c [43852]
    3. chain f,e [43853]
    4. chain h,g [43854]
    5. chain j,i [43855]
    6. chain l,k [43856]
12. 1ev6
    complexed with cl, crs, na, zn
    1. chain b,a [43857]
    2. chain d,c [43858]
    3. chain f,e [43859]
    4. chain h,g [43860]
    5. chain j,i [43861]
    6. chain l,k [43862]
13. 1tym
    complexed with cl, tyl, zn
    1. chain b,a [43863]
    2. chain d,c [43864]
14. 1os3
    complexed with cl, zn
    1. chain b,a [87372]
    2. chain d,c [87373]
15. 1tyl
    complexed with cl, tyl, zn
    1. chain b,a [43865]
    2. chain d,c [43866]
16. 1htv
    complexed with zn
    1. chain b,a [61255]
    2. chain d,c [61256]
    3. chain f,e [61257]
    4. chain h,g [61258]
    5. chain j,i [61259]
    6. chain l,k [61260]
17. 1znj
    complexed with cl, iph, zn
    1. chain b,a [43867]
    2. chain d,c [43868]
    3. chain f,e [43869]
    4. chain h,g [43870]
    5. chain j,i [43871]
    6. chain l,k [43872]
18. 1qiz
    complexed with cl, rco, zn; mutant
    1. chain b,a [43873]
    2. chain d,c [43874]
    3. chain f,e [43875]
    4. chain h,g [43876]
    5. chain j,i [43877]
    6. chain l,k [43878]
19. 1q4v
    complexed with iph, zn
    1. chain b,a [95830]
    2. chain d,c [95831]
20. 1j73
    an unstable insulin analog with native activity
    complexed with dab, zn; mutant
    1. chain b,a [62670]
    2. chain d,c [62671]
21. 1qiy
    complexed with cl, iph, zn; mutant
    1. chain b,a [43879]
    2. chain d,c [43880]
    3. chain f,e [43881]
    4. chain h,g [43882]
    5. chain j,i [43883]
    6. chain l,k [43884]
22. 1jca
    an unstable insulin analog with enhanced(?) activity
    complexed with zn; mutant
    1. chain b,a [62874]
    2. chain d,c [62875]
23. 1b9e
    1. chain b,a [43885]
    2. chain d,c [43886]
24. 1os4
    complexed with zn
    1. chain b,a [87374]
    2. chain d,c [87375]
    3. chain f,e [87376]
    4. chain h,g [87377]
    5. chain j,i [87378]
    6. chain l,k [87379]
25. 1qj0
    complexed with cl, zn; mutant
    1. chain b,a [43889]
    2. chain d,c [43890]
26. 1lph
    complexed with cl, iph, zn; mutant
    1. chain b,a [43887]
    2. chain d,c [43888]
27. 1efe
    an active mini-proinsulin, m2pi
    1. chain a [43891]
28. 1fub
    complexed with cl, na, zn
    1. chain b,a [43892]
    2. chain d,c [43893]
29. 1fu2
    complexed with cl, na, zn
    1. chain b,a [43906]
    2. chain d,c [43907]
    3. chain f,e [43908]
    4. chain h,g [43909]
30. 2aiy
    complexed with iph
    1. chain b,a [43918]
    2. chain d,c [43919]
    3. chain f,e [43920]
    4. chain h,g [43921]
    5. chain j,i [43922]
    6. chain l,k [43923]
31. 1hiq
    mutant
    1. chain b,a [43936]
32. 1hit
    mutant
    1. chain b,a [43937]
33. 5aiy
    complexed with iph
    1. chain b,a [43894]
    2. chain d,c [43895]
    3. chain f,e [43896]
    4. chain h,g [43897]
    5. chain j,i [43898]
    6. chain l,k [43899]
34. 1bzv
    superpotent single-replacement insulin analogue
    mutant
    1. chain b,a [43942]
35. 1his
    1. chain b,a [43938]
36. 4aiy
    complexed with iph
    1. chain b,a [43900]
    2. chain d,c [43901]
    3. chain f,e [43902]
    4. chain h,g [43903]
    5. chain j,i [43904]
    6. chain l,k [43905]
37. 1xgl
    1. chain b,a [43939]
38. 1aiy
    complexed with iph, zn
    1. chain b,a [43930]
    2. chain d,c [43931]
    3. chain f,e [43932]
    4. chain h,g [43933]
    5. chain j,i [43934]
    6. chain l,k [43935]
39. 1ai0
    complexed with iph, zn
    1. chain b,a [43924]
    2. chain d,c [43925]
    3. chain f,e [43926]
    4. chain h,g [43927]
    5. chain j,i [43928]
    6. chain l,k [43929]
40. 1hls
    mutant
    1. chain b,a [43910]
41. 1a7f
    mutant
    1. chain b,a [43943]
42. 1kmf
    mutant
    1. chain b,a [68694]
43. 1mhi
    mutant
    1. chain b,a [43945]
44. 1lnp
    mutant
    1. chain b,a [74048]
45. 1t1q
    complexed with aba; mutant
    1. chain b,a [106261]
46. 1lkq
    mutant
    1. chain b,a [73979]
47. 3aiy
    complexed with iph
    1. chain b,a [43911]
    2. chain d,c [43912]
    3. chain f,e [43913]
    4. chain h,g [43914]
    5. chain j,i [43915]
    6. chain l,k [43916]
48. 1t1p
    mutant
    1. chain b,a [106260]
49. 1t1k
    mutant
    1. chain b,a [106251]
50. 1mhj
    mutant
    1. chain b,a [43947]
51. 1hui
    mutant
    1. chain b,a [43940]
52. 1ioh
    mutant
    1. chain b,a [43941]
53. 1k3m
    mutant
    1. chain b,a [68117]
54. 2hiu
    1. chain b,a [43948]
55. 1iog
    mutant
    1. chain b,a [43944]
56. 1sjt
    mutant
    1. chain b,a [43946]
57. 1vkt
    mutant
    1. chain b,a [43949]
58. 1sf1
    solution structure under amyloidogenic condition
    1. chain b,a [98827]
59. 1jco
    a monomeric mutant (PT insulin)
    Alpha-galactosidase agl1
    mutant
    1. chain b,a [66503]
60. 1sju
    single chain insulin analog mutant
    1. chain a [43950]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk