Structural Classification of Proteins
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Family: Lesion bypass DNA polymerase (Y-family), catalytic domain

contains a distinct 'fingers' domain possibly related to the C-terminal subdomain of hypothetical protein Ta1206 (1qw2)

Lineage:

  1. Root: scop
  2. Class: Multi-domain proteins (alpha and beta) [56572]
    Folds consisting of two or more domains belonging to different classes
  3. Fold: DNA/RNA polymerases [56671]
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. Superfamily: DNA/RNA polymerases [56672]
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
    link to SUPERFAMILY database - Superfamily
  5. Family: Lesion bypass DNA polymerase (Y-family), catalytic domain [100888]
    contains a distinct 'fingers' domain possibly related to the C-terminal subdomain of hypothetical protein Ta1206 (1qw2)

Protein Domains:

  1. DinB homolog (DBH) [100889]
    1. Archaeon Sulfolobus solfataricus, DNA polymerase IV [TaxId: 2287] [100890] (62)
      1. 1jx4 picpicxref
        complexed with adi, ca, mg
        1. region a:1-240 [90379] picpiclink
      2. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddy, mg
        1. region a:2-240 [118914] picpiclink
      3. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddy, mg
        1. region b:2-240 [118916] picpiclink
      4. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddy, mg
        1. region c:2-240 [118918] picpiclink
      5. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddy, mg
        1. region d:2-240 [118920] picpiclink
      6. 2jej picpicxref
        automatically matched to d1jx4a2
        complexed with bzg, ca, dgt
        1. region a:2-240 [138285] picpiclink
      7. 1rys picpicxref
        complexed with atp, ca, edo, na
        1. region a:1-240 [98112] picpiclink
        2. region b:1-240 [98114] picpiclink
      8. 2asd picpicxrefxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dcp, ddg
        1. region a:2-240 [127249] picpiclink
      9. 2asd picpicxrefxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dcp, ddg
        1. region b:1002-1240 [127251] picpiclink
      10. 2rdi picpicxref
        automatically matched to d1jx4a2
        complexed with gol, peg
        1. region a:1-240 [151929] picpiclink
      11. 1s10 picpicxref
        complexed with ca, dcp
        1. region a:1-240 [98328] picpiclink
      12. 1s0o picpicxref
        complexed with ca, mg, ttp
        1. region a:1-240 [98297] picpiclink
        2. region b:1-240 [98299] picpiclink
      13. 2imw picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dad, edo
        1. region p:2-240 [137520] picpiclink
      14. 2agq picpicxref
        automatically matched to d1jx4a2
        complexed with ca, doc, dtp, mg
        1. region a:2-240 [126736] picpiclink
      15. 2bq3 picpicxref
        automatically matched to d1jx4a2
        complexed with ca, gne
        1. region a:2-240 [128960] picpiclink
      16. 2uvv picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dgt; mutant
        1. region a:1-240 [139985] picpiclink
      17. 2br0 picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dg3, gne
        1. region a:2-240 [128974] picpiclink
      18. 1jxl picpicxref
        complexed with bro, ca, dg3, edo, mg
        1. region a:1-240 [90381] picpiclink
      19. 1n48 picpicxref
        complexed with 3dr, atp, ca
        1. region a:1-240 [91616] picpiclink
      20. 2uvw picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dgt; mutant
        1. region a:1-240 [139987] picpiclink
      21. 2rdj picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, gol, tmp
        1. region a:1-240 [151931] picpiclink
      22. 2rdj picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, gol, tmp
        1. region b:1-240 [151933] picpiclink
      23. 2jef picpicxref
        automatically matched to d1jx4a2
        complexed with bzg, ca, dgt, doc
        1. region a:2-240 [138279] picpiclink
      24. 2c28 picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dg3
        1. region a:2-240 [129661] picpiclink
      25. 2jeg picpicxref
        automatically matched to d1jx4a2
        complexed with bzg, ca, dgt, doc
        1. region a:2-240 [138281] picpiclink
      26. 2ibk picpicxref
        automatically matched to d1jx4a2
        complexed with bap, ca, edo, gol, pop
        1. region a:1-240 [147599] picpiclink
      27. 1ryr picpicxref
        complexed with atp, ca
        1. region a:1-240 [98110] picpiclink
      28. 2bqr picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dtp, gne
        1. region a:2-240 [128966] picpiclink
      29. 1s97 picpicxref
        complexed with ca, dct
        1. region a:1-240 [98743] picpiclink
        2. region b:1-240 [98745] picpiclink
        3. region c:1-240 [98747] picpiclink
        4. region d:1-240 [98749] picpiclink
      30. 2j6u picpicxref
        automatically matched to d1jx4a2
        complexed with 6og, ca, dgt
        1. region a:5-243 [138094] picpiclink
      31. 1n56 picpicxref
        complexed with 3dr, atp, ca, mg
        1. region a:1-240 [91681] picpiclink
        2. region b:1-240 [91683] picpiclink
      32. 2r8i picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dtp, p; mutant
        1. region a:1-240 [151722] picpiclink
      33. 2bqu picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dad, gne
        1. region a:2-240 [128968] picpiclink
      34. 2jei picpicxref
        automatically matched to d1jx4a2
        complexed with bzg, ca, dgt
        1. region a:2-240 [138283] picpiclink
      35. 1s0m picpicxref
        complexed with atp, bpa, ca, mg
        1. region a:1-240 [98291] picpiclink
        2. region b:1-240 [98293] picpiclink
      36. 2r8h picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dgt, p; mutant
        1. region a:1-240 [151720] picpiclink
      37. 2j6s picpicxref
        automatically matched to d1jx4a2
        complexed with 6og, ca, dtp
        1. region a:1-240 [138090] picpiclink
      38. 2c22 picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dgt
        1. region a:2-240 [129656] picpiclink
      39. 2agp picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dgt, doc, mg
        1. region a:2-240 [126732] picpiclink
      40. 2agp picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dgt, doc, mg
        1. region b:2-240 [126734] picpiclink
      41. 2j6t picpicxref
        automatically matched to d1jx4a2
        complexed with 6og, ca, dtp
        1. region a:2-240 [138092] picpiclink
      42. 2r8g picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dgt, p; mutant
        1. region a:1-240 [151718] picpiclink
      43. 2ago picpicxref
        automatically matched to d1jx4a2
        complexed with ca, mg, pop
        1. region a:2-240 [126730] picpiclink
      44. 2asj picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddg
        1. region a:2-240 [127255] picpiclink
      45. 2asj picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddg
        1. region b:1002-1240 [127257] picpiclink
      46. 2c2d picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dtp
        1. region a:2-240 [129665] picpiclink
      47. 2uvu picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dgt; mutant
        1. region a:1-240 [139983] picpiclink
      48. 1s0n picpicxref
        complexed with ca, dcp
        1. region a:1-240 [98295] picpiclink
      49. 2va2 picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dct, dft
        1. region a:1-240 [152816] picpiclink
      50. 2va2 picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dct, dft
        1. region b:1-240 [152818] picpiclink
      51. 2asl picpicxrefxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, doc
        1. region a:2-240 [127259] picpiclink
      52. 2asl picpicxrefxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, doc
        1. region b:1002-1240 [127261] picpiclink
      53. 2atl picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dcp, ddg
        1. region a:2-240 [127297] picpiclink
      54. 2atl picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dcp, ddg
        1. region b:1002-1240 [127299] picpiclink
      55. 2c2r picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dct, doc
        1. region a:2-240 [129681] picpiclink
      56. 2uvr picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dgt; mutant
        1. region a:1-240 [139981] picpiclink
      57. 2va3 picpicxref
        automatically matched to d1jx4a2
        complexed with ca, dft, dgt
        1. region a:1-240 [152820] picpiclink
      58. 2c2e picpicxref
        automatically matched to d1jx4a2
        complexed with 8og, ca, dcp
        1. region a:2-240 [129667] picpiclink
      59. 2v9w picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dct, dft
        1. region a:1-240 [152812] picpiclink
      60. 2v9w picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, dct, dft
        1. region b:1-240 [152814] picpiclink
      61. 2au0 picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddg
        1. region a:2-240 [127319] picpiclink
      62. 2au0 picpicxrefxref
        automatically matched to d1jx4a2
        complexed with ca, ddg
        1. region b:1002-1240 [127321] picpiclink
    2. Archaeon Sulfolobus solfataricus [TaxId: 2287] [100891] (3)
      1. 1im4 picpic
        "palm" and "fingers" domains only
        complexed with so4
        1. chain a [62581] picpiclink
      2. 1k1s picpicxref
        mutant
        1. region a:1-239 [90387] picpiclink
      3. 1k1q picpicxref
        mutant
        1. region a:1-239 [90383] picpiclink
        2. region b:1-239 [90385] picpiclink
    3. Sulfolobus acidocaldarius Brock et al. 1972 (Sulfolobus acidocaldarius) [TaxId: 2285] [160954] (3)
      1. 3bq1 picpicxref
        automatically matched to d1k1qa2
        complexed with ca, dg3
        1. region a:1-239 [155494] picpiclink
      2. 3bq0 picpicxref
        automatically matched to d1k1qa2
        complexed with ca
        1. region a:1-239 [155492] picpiclink
      3. 3bq2 picpicxref
        automatically matched to d1k1qa2
        complexed with ca
        1. region a:1-239 [155496] picpiclink
  2. DNA polymerase eta [100892]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [100893] (5)
      1. 1jih picpicxref
        1. region a:1-389 [90375] picpiclink
        2. region b:1-389 [90377] picpiclink
      2. 2r8j picpicxrefxref
        automatically matched to d1jiha2
        complexed with ca, cpt, dcp
        1. region a:1-389 [151724] picpiclink
      3. 2r8j picpicxrefxref
        automatically matched to d1jiha2
        complexed with ca, cpt, dcp
        1. region b:1-389 [151726] picpiclink
      4. 2r8k picpicxrefxref
        automatically matched to d1jiha2
        complexed with 2oa, ca, cpt
        1. region a:1-389 [151728] picpiclink
      5. 2r8k picpicxrefxref
        automatically matched to d1jiha2
        complexed with 2oa, ca, cpt
        1. region b:1-389 [151730] picpiclink
  3. DNA polymerase iota [111295]
    1. Human (Homo sapiens) [TaxId: 9606] [111296] (8)
      SQ Q9UNA4
      1. 1zet picpicxref
        automatically matched to d1t3na2
        complexed with bru, doc, mg, ttp
        1. region a:27-299 [124998] picpiclink
      2. 2dpi picpicxref
        automatically matched to d1t3na2
        complexed with dcp, doc, eda, mg
        1. region a:27-299 [131613] picpiclink
      3. 2dpj picpicxref
        automatically matched to d1t3na2
        complexed with doc, eda, mg, ttp
        1. region a:27-299 [131615] picpiclink
      4. 2flp picpicxref
        automatically matched to d1t3na2
        complexed with doc
        1. region a:27-299 [133746] picpiclink
      5. 1t3n picpicxref
        complexed with doc, mg, ttp
        1. region a:27-299 [106364] picpiclink
        2. region b:447-719 [106366] picpiclink
      6. 2alz picpicxref
        automatically matched to d1t3na2
        complexed with dcp, doc, mg
        1. region a:27-299 [126995] picpiclink
      7. 2fln picpicxref
        automatically matched to d1t3na2
        complexed with doc
        1. region a:27-299 [133732] picpiclink
      8. 2fll picpicxref
        automatically matched to d1t3na2
        complexed with doc, mg, ttp
        1. region a:27-299 [133728] picpiclink
  4. DNA polymerase kappa [111297]
    1. Human (Homo sapiens) [TaxId: 9606] [111298] (1)
      SQ Q9UBT6 71-517
      1. 1t94 picpicxref
        1. region a:75-407 [106702] picpiclink
        2. region b:75-407 [106704] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk