Structural Classification of Proteins
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Fold: beta-hairpin-alpha-hairpin repeat

multiple repeats of beta(2)-alpha(2) motif

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: beta-hairpin-alpha-hairpin repeat [74651]
    multiple repeats of beta(2)-alpha(2) motif

Superfamilies:

  1. Ankyrin repeat [48403] (1)
    repeats organized in elongated structures
    link to SUPERFAMILY database - Superfamily
    1. Ankyrin repeat [48404] (20)
      1. Ankyrin-R [82632]
        1. Human (Homo sapiens) [TaxId: 9606] [82633] (1) picpic
      2. 53BP2 [48405]
        1. Human (Homo sapiens) [TaxId: 9606] [48406] (1) picpic
      3. GA bindinig protein (GABP) beta 1 [48407]
        1. Mouse (Mus musculus) [TaxId: 10090] [48408] (1) picpic
      4. Cell cycle inhibitor p19ink4D [48409]
        1. Human (Homo sapiens) [TaxId: 9606] [48410] (2) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [48411] (1) picpic
      5. p18ink4C(ink6) [48412]
        1. Human (Homo sapiens) [TaxId: 9606] [48413] (6) picpic
      6. Cell cycle inhibitor p16ink4A [48414]
        1. Human (Homo sapiens) [TaxId: 9606] [48415] (4) picpic
        2. Mouse (Mus musculus) [TaxId: 10090] [48416] (1) picpic
      7. I-kappa-B-alpha [48417]
        1. Human (Homo sapiens) [TaxId: 9606] [48418] (2) picpic
      8. bcl-3 [69091]
        a member of the I-kappa-B family
        1. Human (Homo sapiens) [TaxId: 9606] [69092] (2) picpic
      9. Transcription factor inhibitor I-kappa-B-beta, IKBB [82634]
        1. Mouse (Mus musculus) [TaxId: 10090] [82635] (2) picpic
      10. Myotrophin [48419]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [48420] (2) picpic
      11. Swi6 ankyrin-repeat fragment [48421]
        interrupted by an insertion
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [48422] (1) picpic
      12. Pyk2-associated protein beta [48423]
        1. Mouse (Mus musculus) [TaxId: 10090] [48424] (1) picpic
      13. Neurogenic locus notch receptor domain [102879]
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [102880] (1) picpic
      14. 26S proteasome non-ATPase regulatory subunit 10, gankyrin [102881]
        1. Human (Homo sapiens) [TaxId: 9606] [102882] (3) picpic
          SQ O75832
        2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [102883] (7) picpic
      15. Myosin phosphatase targeting subunit 1, MYPT1 [110891]
        1. Chicken (Gallus gallus) [TaxId: 9031] [110892] (1) picpic
          SQ Q90623 1-299
      16. RNase L, 2-5a-dependent ribonuclease [117879]
        1. Human (Homo sapiens) [TaxId: 9606] [117880] (1) picpic
          SQ Q05823 21-305
      17. Lin-12 [160152]
        1. Caenorhabditis elegans [TaxId: 6239] [160153] (1) picpic
          SQ P14585 1021-1297
  2. Plakin repeat [75399] (1)
    repeats associate forming globular subdomains
    link to SUPERFAMILY database - Superfamily
    1. Plakin repeat [75400] (1)
      1. Desmoplakin intermediate filament-binding domains [75401]
        1. Human (Homo sapiens) [TaxId: 9606] [75402] (2) picpic

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk