Structural Classification of Proteins
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Fold: beta-hairpin-alpha-hairpin repeat

multiple repeats of beta(2)-alpha(2) motif

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: beta-hairpin-alpha-hairpin repeat [74651]
    multiple repeats of beta(2)-alpha(2) motif

Superfamilies:

  1. Ankyrin repeat [48403] (1)
    repeats organized in elongated structures
    link to SUPERFAMILY database - Superfamily
    1. Ankyrin repeat [48404] (20)
      1. Ankyrin-R [82632]
        1. Human (Homo sapiens) [TaxId: 9606] [82633] (1)
          1. 1n11 picpic
            D34 region (12 repeats) and linker
            complexed with br, cl
            1. chain a [79778] picpiclink
      2. 53BP2 [48405]
        1. Human (Homo sapiens) [TaxId: 9606] [48406] (1)
          1. 1ycs picpicxrefxref
            complexed with zn
            1. region b:327-456 [19155] picpiclink
      3. GA bindinig protein (GABP) beta 1 [48407]
        1. Mouse (Mus musculus) [TaxId: 10090] [48408] (1)
          1. 1awc picpicxref
            protein/DNA complex; complexed with bro
            1. chain b [19156] picpiclink
      4. Cell cycle inhibitor p19ink4D [48409]
        1. Human (Homo sapiens) [TaxId: 9606] [48410] (2)
          1. 1bd8 picpic
            1. chain a [19157] picpiclink
          2. 1bi8 picpicxref
            1. chain b [19158] picpiclink
            2. chain d [19159] picpiclink
        2. Mouse (Mus musculus) [TaxId: 10090] [48411] (1)
          1. 1blx picpicxref
            complexed with ca
            1. chain b [19160] picpiclink
      5. p18ink4C(ink6) [48412]
        1. Human (Homo sapiens) [TaxId: 9606] [48413] (6)
          1. 1ihb picpic
            1. chain a [19161] picpiclink
            2. chain b [19162] picpiclink
          2. 1mx4 picpic
            mutant
            1. chain a [79640] picpiclink
            2. chain b [79641] picpiclink
          3. 1mx6 picpic
            mutant
            1. chain a [79642] picpiclink
            2. chain b [79643] picpiclink
          4. 1mx2 picpic
            mutant
            1. chain a [79636] picpiclink
            2. chain b [79637] picpiclink
          5. 1g3n picpicxrefxref
            1. chain b [19163] picpiclink
            2. chain f [19164] picpiclink
          6. 1bu9 picpic
            1. chain a [19165] picpiclink
      6. Cell cycle inhibitor p16ink4A [48414]
        1. Human (Homo sapiens) [TaxId: 9606] [48415] (4)
          1. 1bi7 picpicxref
            1. chain b [19166] picpiclink
          2. 2a5e picpic
            1. chain a [19167] picpiclink
          3. 1a5e picpic
            1. chain a [19169] picpiclink
          4. 1dc2 picpic
            1. chain a [19168] picpiclink
        2. Mouse (Mus musculus) [TaxId: 10090] [48416] (1)
          1. 1ap7 picpic
            1. chain a [19170] picpiclink
      7. I-kappa-B-alpha [48417]
        1. Human (Homo sapiens) [TaxId: 9606] [48418] (2)
          1. 1ikn picpicxrefxrefxref
            1. chain d [19171] picpiclink
          2. 1nfi picpicxrefxrefxref
            1. chain e [19172] picpiclink
            2. chain f [19173] picpiclink
      8. bcl-3 [69091]
        a member of the I-kappa-B family
        1. Human (Homo sapiens) [TaxId: 9606] [69092] (2)
          1. 1k1a picpic
            1. chain a [67992] picpiclink
          2. 1k1b picpic
            1. chain a [67993] picpiclink
      9. Transcription factor inhibitor I-kappa-B-beta, IKBB [82634]
        1. Mouse (Mus musculus) [TaxId: 10090] [82635] (2)
          1. 1oy3 picpicxref
            1. chain d [87554] picpiclink
          2. 1k3z picpicxref
            mutant
            1. chain d [77251] picpiclink
      10. Myotrophin [48419]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [48420] (2)
          1. 1myo picpic
            1. chain a [19174] picpiclink
          2. 2myo picpic
            1. chain a [19175] picpiclink
      11. Swi6 ankyrin-repeat fragment [48421]
        interrupted by an insertion
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [48422] (1)
          1. 1sw6 picpic
            1. chain a [19176] picpiclink
            2. chain b [19177] picpiclink
      12. Pyk2-associated protein beta [48423]
        1. Mouse (Mus musculus) [TaxId: 10090] [48424] (1)
          1. 1dcq picpicxref
            1. region a:369-522 [19178] picpiclink
      13. Neurogenic locus notch receptor domain [102879]
        1. Fruit fly (Drosophila melanogaster) [TaxId: 7227] [102880] (1)
          1. 1ot8 picpic
            complexed with mg
            1. chain a [93507] picpiclink
            2. chain b [93508] picpiclink
            3. chain c [93509] picpiclink
      14. 26S proteasome non-ATPase regulatory subunit 10, gankyrin [102881]
        1. Human (Homo sapiens) [TaxId: 9606] [102882] (3)
          SQ O75832
          1. 1uoh picpic
            1. chain a [99690] picpiclink
          2. 1qym picpic
            1. chain a [96596] picpiclink
          3. 1tr4 picpic
            1. chain a [112616] picpiclink
        2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [102883] (7)
          1. 1ixv picpic
            1. chain a [90719] picpiclink
          2. 1wg0 picpic
            automatically matched to d1ixva_
            1. region a:3-230 [120971] picpiclink
          3. 2dzn picpic
            automatically matched to d1ixva_
            1. region a:3-228 [146617] picpiclink
          4. 2dzn picpic
            automatically matched to d1ixva_
            1. region c:3-228 [146618] picpiclink
          5. 2dzn picpic
            automatically matched to d1ixva_
            1. region e:3-228 [146619] picpiclink
          6. 2dzo picpic
            automatically matched to d1ixva_
            1. region a:3-228 [146620] picpiclink
          7. 2dzo picpic
            automatically matched to d1ixva_
            1. region c:3-228 [146621] picpiclink
      15. Myosin phosphatase targeting subunit 1, MYPT1 [110891]
        1. Chicken (Gallus gallus) [TaxId: 9031] [110892] (1)
          SQ Q90623 1-299
          1. 1s70 picpicxref
            complexed with mn, pge; mutant
            1. chain b [105317] picpiclink
      16. RNase L, 2-5a-dependent ribonuclease [117879]
        1. Human (Homo sapiens) [TaxId: 9606] [117880] (1)
          SQ Q05823 21-305
          1. 1wdy picpic
            complexed with 25a; mutant
            1. chain a [114541] picpiclink
      17. Lin-12 [160152]
        1. Caenorhabditis elegans [TaxId: 6239] [160153] (1)
          SQ P14585 1021-1297
          1. 2fo1 picpicxrefxrefxrefxref
            1. region e:1021-1297 [145176] picpiclink
  2. Plakin repeat [75399] (1)
    repeats associate forming globular subdomains
    link to SUPERFAMILY database - Superfamily
    1. Plakin repeat [75400] (1)
      1. Desmoplakin intermediate filament-binding domains [75401]
        1. Human (Homo sapiens) [TaxId: 9606] [75402] (2)
          1. 1lm5 picpic
            domain C (residues 2609-2822)
            1. chain a [74029] picpiclink
            2. chain b [74030] picpiclink
          2. 1lm7 picpic
            domain B (residues 2209-2456)
            1. chain a [74031] picpiclink
            2. chain b [74032] picpiclink

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site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk