Structural Classification of Proteins
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Fold: Substrate-binding domain of HMG-CoA reductase

unusual fold

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Substrate-binding domain of HMG-CoA reductase [56541]
    unusual fold

Superfamilies:

  1. Substrate-binding domain of HMG-CoA reductase [56542] (1)
    link to SUPERFAMILY database - Superfamily
    1. Substrate-binding domain of HMG-CoA reductase [56543] (2)
      1. Substrate-binding domain of HMG-CoA reductase [56544]
        1. Human (Homo sapiens) [TaxId: 9606] [56545] (9)
          1. 1dqa picpicxref
            complexed with coa, mah, nap; mutant
            1. region a:462-586,a:704-870 [42585] picpiclink
            2. region b:462-586,b:704-866 [42586] picpiclink
            3. region c:468-586,c:704-871 [42587] picpiclink
            4. region d:477-586,d:704-872 [42588] picpiclink
          2. 1hw8 picpicxref
            complexed with 114, adp; mutant
            1. region a:441-586,a:704-861 [61299] picpiclink
            2. region b:443-586,b:704-860 [61301] picpiclink
            3. region c:488-586,c:704-860 [61303] picpiclink
            4. region d:488-586,d:704-859 [61305] picpiclink
          3. 1dq8 picpicxref
            complexed with coa, dtt, mah; mutant
            1. region a:439-586,a:704-863 [42589] picpiclink
            2. region b:461-586,b:704-865 [42590] picpiclink
            3. region c:464-586,c:704-865 [42591] picpiclink
            4. region d:458-586,d:704-864 [42592] picpiclink
          4. 1hwl picpicxref
            complexed with adp, fbi; mutant
            1. region a:442-586,a:704-860 [61339] picpiclink
            2. region b:463-586,b:704-860 [61341] picpiclink
            3. region c:463-586,c:704-860 [61343] picpiclink
            4. region d:479-586,d:704-860 [61345] picpiclink
          5. 1hwi picpicxref
            complexed with 115, adp; mutant
            1. region a:462-586,a:704-862 [61315] picpiclink
            2. region b:462-586,b:704-860 [61317] picpiclink
            3. region c:489-586,c:704-862 [61319] picpiclink
            4. region d:487-586,d:704-860 [61321] picpiclink
          6. 1hwj picpicxref
            complexed with 116, adp; mutant
            1. region a:442-586,a:704-861 [61323] picpiclink
            2. region b:463-586,b:704-860 [61325] picpiclink
            3. region c:442-586,c:704-860 [61327] picpiclink
            4. region d:462-586,d:704-860 [61329] picpiclink
          7. 1hwk picpicxref
            complexed with 117, adp; mutant
            1. region a:442-586,a:704-861 [61331] picpiclink
            2. region b:463-586,b:704-860 [61333] picpiclink
            3. region c:462-586,c:704-860 [61335] picpiclink
            4. region d:463-586,d:704-860 [61337] picpiclink
          8. 1hw9 picpicxref
            complexed with adp, sim; mutant
            1. region a:442-586,a:704-860 [61307] picpiclink
            2. region b:463-586,b:704-860 [61309] picpiclink
            3. region c:463-586,c:704-860 [61311] picpiclink
            4. region d:464-586,d:704-859 [61313] picpiclink
          9. 1dq9 picpicxref
            complexed with hmg; mutant
            1. region a:461-586,a:704-865 [42593] picpiclink
            2. region b:460-586,b:704-864 [42594] picpiclink
            3. region c:460-586,c:704-866 [42595] picpiclink
            4. region d:453-586,d:704-865 [42596] picpiclink
        2. Pseudomonas mevalonii [TaxId: 32044] [56546] (5)
          SQ P13702 4-377
          1. 1r31 picpicxref
            complexed with coa, mev, so4
            1. region a:3-110,a:221-378 [96898] picpiclink
            2. region b:503-610,b:721-877 [96900] picpiclink
          2. 1r7i picpicxref
            complexed with gol, so4
            1. region a:3-110,a:221-374 [97199] picpiclink
            2. region b:503-610,b:721-877 [97201] picpiclink
          3. 1t02 picpicxref
            complexed with lva, so4
            1. region a:4-110,a:221-374 [106191] picpiclink
            2. region b:4-110,b:221-374 [106193] picpiclink
          4. 1qay picpicxref
            complexed with mev, nad
            1. region a:4-110,a:221-387 [42599] picpiclink
            2. region b:504-610,b:721-877 [42600] picpiclink
          5. 1qax picpicxref
            complexed with hmg, nad
            1. region a:4-110,a:221-428 [42597] picpiclink
            2. region b:504-610,b:721-875 [42598] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk