Fold: FAH

unusual fold; contains 3 layers of beta-sheet structure

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: FAH [56528]
   unusual fold; contains 3 layers of beta-sheet structure

Superfamilies:

1. FAH [56529] (1)
   uperfamily
   1. FAH [56530] (6)
      1. Fumarylacetoacetate hydrolase, FAH, C-terminal domain [63432]
         1. Mouse (Mus musculus) [TaxId: 10090] [56532] (6)
            1. 1hyo
               complexed with act, ca, hbu, mg, ni
               1. region a:119-416 [59002]
               2. region b:619-917 [59004]
            2. 2hzy
               automatically matched to d1qcnb2
               complexed with ca, dhj, mn, na, ni
               1. region a:119-416 [136933]
            3. 2hzy
               automatically matched to d1qcnb2
               complexed with ca, dhj, mn, na, ni
               1. region b:119-416 [136935]
            4. 1qqj
               complexed with act, ca, cac
               1. region a:119-416 [59035]
               2. region b:119-416 [59037]
            5. 1qco
               complexed with aae, ca, fum, ni
               1. region a:119-417 [59022]
               2. region b:619-917 [59024]
            6. 1qcn
               complexed with act, ca, ni
               1. region a:119-417 [59018]
               2. region b:619-918 [59020]
      2. Putative isomerase YcgM [90070]
         1. Escherichia coli [TaxId: 562] [90071] (1)
            1. 1nr9
               structural genomics
               complexed with mg, mse
               1. chain a [86119]
               2. chain b [86120]
               3. chain c [86121]
               4. chain d [86122]
      3. 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpcE [64459]
         duplication: tandem repeat of two FAH domains
         1. Escherichia coli [TaxId: 562] [64460] (2)
            1. 1gtt
               complexed with ca
               1. region a:1-213 [70529]
               2. region a:214-429 [70530]
               3. region b:1-213 [70531]
               4. region b:214-429 [70532]
               5. region c:1-213 [70533]
               6. region c:214-429 [70534]
               7. region d:1-213 [70535]
               8. region d:214-429 [70536]
            2. 1i7o
               complexed with ca
               1. region a:1-213 [61893]
               2. region a:214-429 [61894]
               3. region b:1-213 [61895]
               4. region b:214-429 [61896]
               5. region c:1-213 [61897]
               6. region c:214-429 [61898]
               7. region d:1-213 [61899]
               8. region d:214-429 [61900]
      4. Hypothetical protein Ynl168c [111272]
         1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [111273] (1)
            SQ P53889
            1. 1nkq
               Structural genomics target
               complexed with acy, ca, so4
               1. chain a [103862]
               2. chain b [103863]
               3. chain c [103864]
               4. chain d [103865]
               5. chain e [103866]
               6. chain f [103867]
      5. 2-keto-4-pentenoate hydratase MhpD [111274]
         1. Escherichia coli [TaxId: 562] [111275] (1)
            SQ P77608
            1. 1sv6
               Structural genomics target
               1. chain a [106043]
               2. chain b [106044]
               3. chain c [106045]
               4. chain d [106046]
               5. chain e [106047]
      6. FAHD1 (Flj36880, YISKL) [118170]
         1. Human (Homo sapiens) [TaxId: 9606] [118171] (1)
            SQ Q6P587
            1. 1saw
               complexed with cl, mg
               1. chain a [112050]
               2. chain b [112051]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk