Structural Classification of Proteins
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Superfamily: NTF2-like

has a beta-alpha(2)-beta insertion after the main helix
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Cystatin-like [54402]
    Core: alpha-beta(4); helix packs against coiled antiparallel beta-sheet
  4. Superfamily: NTF2-like [54427]
    has a beta-alpha(2)-beta insertion after the main helix
    link to SUPERFAMILY database - Superfamily

Families:

  1. Scytalone dehydratase [54428] (1)
    1. Scytalone dehydratase [54429]
      1. Fungus (Magnaporthe grisea) [TaxId: 148305] [54430] (8) picpic
  2. NTF2-like [54431] (11)
    1. Nuclear transport factor-2 (NTF2) [54432]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [54433] (10) picpic
        SQ P61972
      2. Human (Homo sapiens) [TaxId: 9606] [75373] (1) picpic
      3. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [75374] (2) picpic
      4. Cryptosporidium parvum [TaxId: 5807] [159958] (2) picpic
        SQ Q5CQI4 4-127
    2. NTF2-related export protein 1 (p15) [69675]
      1. Human (Homo sapiens) [TaxId: 9606] [69676] (2) picpic
    3. NTF2-like domain of Tip associating protein, TAP [69677]
      1. Human (Homo sapiens) [TaxId: 9606] [69678] (2) picpic
    4. NTF2-like domain of mRNA export factor MEX67 [89847]
      similar to the TAP domain; forms complex with MTR2 similar to the TAP-p15 complex
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89848] (1) picpic
        Ypl169C
      2. Yeast (Candida albicans) [TaxId: 5476] [102808] (1) picpic
    5. mRNA transport regulator MTR2 [89849]
      similar to p15; forms complex with MEX67 similar to the TAP-p15 complex
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [89850] (1) picpic
        Ykl186C
      2. Yeast (Candida albicans) [TaxId: 5476] [102809] (2) picpic
    6. UBP3-associated protein BRE5 [159959]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [159960] (4) picpic
        SQ P53741 1-141
  3. Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A [89851] (3)
    1. Association domain of calcium/calmodulin-dependent protein kinase type II alpha subunit, CAMK2A [89852]
      1. Mouse (Mus musculus) [TaxId: 10090] [89853] (1) picpic
      2. Caenorhabditis elegans [TaxId: 6239] [159961] (7) picpic
        SQ Q9U6Q0 343-471
      3. Human (Homo sapiens) [TaxId: 9606] [159962] (6) picpic
        SQ Q8N4I3 387-521
  4. Limonene-1,2-epoxide hydrolase-like [89854] (2)
    1. Limonene-1,2-epoxide hydrolase [89855]
      1. Rhodococcus erythropolis [TaxId: 1833] [89856] (2) picpic
    2. Uncharacterized protein Mb2760 [159963]
      1. Mycobacterium tuberculosis [TaxId: 1773] [159964] (3) picpic
        SQ Q7TY00 13-144
  5. SnoaL-like polyketide cyclase [102810] (5)
    1. Nogalonic acid methyl ester cyclase SnoaL [102811]
      1. Streptomyces nogalater [TaxId: 38314] [102812] (1) picpic
    2. Aklanonic acid methyl ester cyclase, AknH [159965]
      1. Streptomyces galilaeus [TaxId: 33899] [159966] (8) picpic
        SQ O52646 2-141
    3. Nogalamycin biosynthesis protein SnoL [159967]
      1. Streptomyces nogalater [TaxId: 38314] [159968] (2) picpic
        SQ Q9RN64 2-139
    4. Putative hydroxylase AclR [159969]
      1. Streptomyces galilaeus [TaxId: 33899] [159970] (2) picpic
        SQ Q1XDX7 2-145
    5. Uncharacterized protein BPSS0132 [159971]
      1. Burkholderia pseudomallei [TaxId: 28450] [159972] (1) picpic
        SQ Q63P16 1-131
  6. PhzA/PhzB-like [102813] (4)
    1. Hypothetical protein YesE [102814]
      1. Bacillus subtilis [TaxId: 1423] [102815] (1) picpic
    2. Uncharacterized protein BTHI0051 [159973]
      1. Burkholderia thailandensis [TaxId: 57975] [159974] (2) picpic
        SQ Q2T2I4 10-139
    3. Uncharacterized protein Ava2261 [159975]
      1. Anabaena variabilis [TaxId: 1172] [159976] (2) picpic
        SQ Q3MAV7 1-133
    4. Uncharacterized protein PA3332 [159977]
      1. Pseudomonas aeruginosa [TaxId: 287] [159978] (1) picpic
        SQ Q9HYR3 1-129
  7. Ketosteroid isomerase-like [54434] (4)
    1. Delta-5-3-ketosteroid isomerase, steroid delta-isomerase, KSI [54435]
      1. Comamonas testosteroni, also known as Pseudomonas testosteroni [TaxId: 285] [54436] (14) picpic
      2. Pseudomonas putida [TaxId: 303] [54437] (23) picpic
        SQ P07445
    2. Hypothetical protein Rv0760c [142994]
      1. Mycobacterium tuberculosis [TaxId: 1773] [142995] (1) picpic
        SQ P71817 5-136
      2. Mycobacterium tuberculosis H37Rv [TaxId: 83332] [159979] (10) picpic
  8. Ring hydroxylating beta subunit [54438] (7)
    Pfam 00866
    1. Naphthalene 1,2-dioxygenase beta subunit [54439]
      1. Pseudomonas putida [TaxId: 303] [54440] (16) picpic
      2. Rhodococcus sp. ncimb12038 [TaxId: 92694] [142996] (6) picpic
        SQ Q7BSK6 6-172
    2. Biphenyl dioxygenase small subunit BphA2 [110824]
      1. Rhodococcus sp. (strain RHA1) [TaxId: 101510] [110825] (2) picpic
        SQ Q53123 11-187
    3. Small subunit of cumene dioxygenase CumA2 [142997]
      1. Pseudomonas fluorescens [TaxId: 294] [142998] (1) picpic
        SQ Q51744 6-186
    4. Nitrobenzene dioxygenase beta subunit, NBDO-beta [142999]
      1. Comamonas sp. JS765 [TaxId: 58226] [143000] (3) picpic
        SQ Q8RTL3 1-194
    5. Putative hydroxylase subunit Saro3860 [159980]
      1. Novosphingobium aromaticivorans [TaxId: 48935] [159981] (1) picpic
        SQ A4XDU4 6-162
    6. Benzoate 1,2-dioxygenase beta subunit BenB [159982]
      1. Burkholderia mallei [TaxId: 13373] [159983] (1) picpic
        SQ Q62E64 1-163
  9. Penicillin binding protein 2a (PBP2A), N-terminal domain [82595] (1)
    some sequence similarity to KSI
    1. Penicillin binding protein 2a (PBP2A), N-terminal domain [82596]
      1. Staphylococcus aureus [TaxId: 1280] [82597] (5) picpic
        SQ O54286 27-668
  10. Orange carotenoid protein, C-terminal domain [82598] (1)
    1. Orange carotenoid protein, C-terminal domain [82599]
      1. Cyanobacteria (Arthrospira maxima) [TaxId: 129910] [82600] (1) picpic
  11. Hypothetical protein egc068 from a soil-derived mobile gene cassette [110826] (1)
    1. Hypothetical protein egc068 from a soil-derived mobile gene cassette [110827]
      1. uncultured organism [TaxId: 155900] [110828] (1) picpic
        SQ Q99IU3
  12. PA1314-like [110829] (1)
    COG4460
    1. Hypothetical protein PA1314 [110830]
      1. Pseudomonas aeruginosa [TaxId: 287] [110831] (1) picpic
        SQ Q9I430
  13. TIM44-like [143001] (2)
    contains extra N-terminal helices but lacks the beta-hairpin in the superfamily-specific insertion
    1. Translocase of inner mitochondrial membrane TIMM44 (TIM44), C-terminal domain [143002]
      1. Human (Homo sapiens) [TaxId: 9606] [143003] (1) picpic
        SQ O43615 270-451
      2. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [159984] (1) picpic
        SQ Q01852 234-425
  14. Sbal0622-like [159985] (1)
    PfamB 002762
    1. Uncharacterized protein Sbal0622 [159986]
      1. Shewanella baltica [TaxId: 62322] [159987] (12) picpic
        SQ A3D088 3-126
  15. CHU142-like [159988] (1)
    single domain covered by PfamB 000743 in the N-terminal part and PfamB 000860 in the C-terminal part
    1. Uncharacterized protein CHU142 [159989]
      1. Cytophaga hutchinsonii [TaxId: 985] [159990] (4) picpic
        SQ Q11V67 1-122
  16. SO0125-like [159991] (2)
    PfamB 003666
    1. Uncharacterized protein Sfri1973 [159992]
      1. Shewanella frigidimarina [TaxId: 56812] [159993] (6) picpic
        SQ Q082J6 23-147
    2. Uncharacterized protein SO0125 [159994]
      1. Shewanella oneidensis [TaxId: 70863] [159995] (1) picpic
        SQ Q8EKG8 1-121
  17. SAV4671-like [159996] (1)
    PfamB 000442; uncertain annotation of some members as 3-dehydroquinate dehydratase
    1. Uncharacterized protein SAV4671 [159997]
      1. Streptomyces avermitilis [TaxId: 33903] [159998] (3) picpic
        SQ Q82EE4 5-157
  18. BxeB1374-like [159999] (2)
    similar dimer to KSI
    1. Uncharacterized protein ECA3500 [160000]
      1. Pectobacterium atrosepticum [TaxId: 29471] [160001] (4) picpic
        SQ Q6D1E8 1-127
    2. Hypothetical protein BxeB1374 [160002]
      1. Burkholderia xenovorans [TaxId: 36873] [160003] (2) picpic
        SQ Q13MU9 1-128
  19. Atu0744-like [160004] (1)
    PfamB 003773
    1. Uncharacterized protein Atu0744 [160005]
      1. Agrobacterium tumefaciens [TaxId: 358] [160006] (2) picpic
        SQ Q7D0S4 1-117
  20. Rpa4348-like [160007] (2)
    PfamB 000085
    1. Uncharacterized protein BxeB2092 [160008]
      1. Burkholderia xenovorans [TaxId: 36873] [160009] (1) picpic
        SQ Q13PU4 1-127
    2. Uncharacterized protein Rpa4348 [160010]
      1. Rhodopseudomonas palustris [TaxId: 1076] [160011] (1) picpic
        SQ Q6N1Q6 1-135
  21. Ava4193-like [160012] (1)
    PfamB 183524
    1. Uncharacterized protein Ava4193 [160013]
      1. Anabaena variabilis [TaxId: 1172] [160014] (4) picpic
        SQ Q3M5E4 2-129
  22. YybH-like [160015] (1)
    PfamB 052627
    1. Hypothetical protein YybH [160016]
      1. Bacillus subtilis [TaxId: 1423] [160017] (4) picpic
        SQ P37496 1-128
  23. PFL3262-like [160018] (1)
    Pfam 07080; DUF1348
    1. Hypothetical protein PFL3262 [160019]
      1. Pseudomonas fluorescens [TaxId: 294] [160020] (4) picpic
        SQ Q4KBL6 5-159
  24. Exig0174-like [160021] (1)
    PfamB 092483
    1. Uncharacterized protein Exig0174 [160022]
      1. Exiguobacterium sibiricum 255-15 [TaxId: 262543] [160023] (2) picpic
        SQ B1YHC8 5-122
  25. Rv3472-like [160024] (2)
    similar trimer to Scytalone dehydratase
    1. Uncharacterized protein NpunR3134 [160025]
      1. Nostoc punctiforme [TaxId: 272131] [160026] (3) picpic
        SQ B2IXS6 1-133
    2. Uncharacterized protein Rv3472 [160027]
      1. Mycobacterium tuberculosis [TaxId: 1773] [160028] (3) picpic
        SQ O06337 1-167
  26. VirB8-like [160029] (2)
    Pfam 04335
    1. Type IV secretion system protein VirB8 [160030]
      1. Agrobacterium tumefaciens [TaxId: 358] [160031] (2) picpic
        SQ P17798 92-231
      2. Brucella melitensis [TaxId: 29459] [160032] (5) picpic
        SQ Q7CEG3 97-235
  27. ECA1476-like [160033] (1)
    single domain covered by PfamB 006272 in the N-terminal part and PfamB 005262 in the C-terminal part
    1. Uncharacterized protein ECA1476 [160034]
      1. Pectobacterium atrosepticum [TaxId: 29471] [160035] (4) picpic
        SQ Q6D750 3-134
  28. BaiE/LinA-like [160036] (5)
    PfamB 000019; includes sequences of characterized enzymes BaiE and LinA
    1. Uncharacterized protein Saro2766 [160037]
      1. Novosphingobium aromaticivorans [TaxId: 48935] [160038] (1) picpic
        SQ Q2G4M1 2-160
    2. Uncharacterized protein Saro3722 [160039]
      1. Novosphingobium aromaticivorans [TaxId: 48935] [160040] (1) picpic
        SQ A4XF70 13-165
    3. Uncharacterized protein Saro1465 [160041]
      1. Novosphingobium aromaticivorans [TaxId: 48935] [160042] (2) picpic
        SQ Q2G8B5 1-149
    4. Uncharacterized protein NpunR1993 [160043]
      1. Nostoc punctiforme [TaxId: 272131] [160044] (1) picpic
        SQ B2J4W9 9-170
    5. Uncharacterized protein Saro3538 [160045]
      1. Novosphingobium aromaticivorans [TaxId: 48935] [160046] (6) picpic
        SQ A4XEN7 1-144
  29. Atu0742-like [160047] (1)
    PfamB 017405
    1. Uncharacterized protein Atu0742 [160048]
      1. Agrobacterium tumefaciens [TaxId: 358] [160049] (1) picpic
        SQ A9CJY7 1-123
  30. SEC-C associated NTF2-like domain [160050] (1)
    there is a C-terminal SEC-C motif, also there can be an additional SEC-C like motif at the N-terminus (there is only C-terminal motif in the new entry 2JQ5)
    1. Hypothetical protein Psyc2064 [160051]
      1. Psychrobacter arcticus [TaxId: 334543] [160052] (1) picpic
        SQ Q4FPZ7 46-158
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk