Structural Classification of Proteins
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Superfamily: Ribosome inactivating proteins (RIP)

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Ribosome inactivating proteins (RIP) [56370]
    contains mixed beta-sheet
  4. Superfamily: Ribosome inactivating proteins (RIP) [56371]
    link to SUPERFAMILY database - Superfamily

Families:

  1. Plant cytotoxins [56372] (17)
    1. alpha-Trichosanthin [56373]
      1. Mongolian snake gourd (Trichosanthes kirilowii Maxim.) [TaxId: 3677] [56374] (10)
        1. 1mrj picpic
          complexed with adn
          1. chain a [42177] picpiclink
        2. 1mrk picpic
          complexed with fmc
          1. chain a [42178] picpiclink
        3. 1gis picpic
          complexed with amp; mutant
          1. chain a [83289] picpiclink
        4. 1nli picpic
          complexed with ade; mutant
          1. chain a [80625] picpiclink
        5. 1tcs picpic
          complexed with ndp
          1. chain a [42179] picpiclink
        6. 1qd2 picpic
          complexed with ade
          1. chain a [42180] picpiclink
        7. 1j4g picpic
          complexed with ca
          1. chain a [66379] picpiclink
          2. chain b [66380] picpiclink
          3. chain c [66381] picpiclink
          4. chain d [66382] picpiclink
        8. 1giu picpic
          complexed with ade; mutant
          1. chain a [83290] picpiclink
        9. 2jdl picpic
          automatically matched to d1mrja_
          1. region a:2-247 [147987] picpiclink
        10. 2jdl picpic
          automatically matched to d1mrja_
          1. region b:2-247 [147988] picpiclink
    2. Bryodin [56375]
      1. Red briony (Bryonia dioica) [TaxId: 3652] [56376] (1)
        1. 1bry picpic
          1. chain y [42181] picpiclink
          2. chain z [42182] picpiclink
    3. Beta-luffin [103331]
      1. Smooth loofah (Luffa cylindrica) [TaxId: 3670] [103332] (1)
        1. 1nio picpic
          complexed with nag
          1. chain a [91890] picpiclink
    4. alpha-Momorcharin (momordin) [56377]
      1. Bitter gourd (Momordica charantia) [TaxId: 3673] [56378] (8)
        1. 1ahc picpic
          1. chain a [42184] picpiclink
        2. 1mrg picpic
          complexed with adn
          1. chain a [42183] picpiclink
        3. 1ahb picpic
          complexed with fmp
          1. chain a [42185] picpiclink
        4. 1aha picpic
          complexed with ade
          1. chain a [42187] picpiclink
        5. 1mom picpic
          complexed with nag
          1. chain a [42188] picpiclink
        6. 1mrh picpic
          complexed with fmc
          1. chain a [42186] picpiclink
        7. 1f8q picpic
          complexed with ccn, man, nag, ptd, xys
          1. chain a [42189] picpiclink
        8. 1mri picpic
          1. chain a [42190] picpiclink
    5. Beta-momorcharin [56379]
      (almost) identical with the anti-tumor and anti-HIV-1 protein MAP30
      1. Bitter gourd (Momordica charantia) [TaxId: 3673] [56380] (2)
        1. 1cf5 picpic
          complexed with bma, fuc, man, nag, xys
          1. chain a [42191] picpiclink
          2. chain b [42192] picpiclink
        2. 1d8v picpic
          1. chain a [42193] picpiclink
    6. Mistletoe lectin I A-chain [56381]
      1. European mistletoe (Viscum album) [TaxId: 3972] [56382] (12)
        different sequence variants
        SQ P81446 1-249
        SQ Q6ITZ3 1-240
        1. 1m2t picpicxref
          complexed with ade, fuc, gol, nag
          1. chain a [84761] picpiclink
        2. 1onk picpicxref
          complexed with azi, gol, nag, po4
          1. chain a [93359] picpiclink
        3. 1sz6 picpicxref
          complexed with azi, cl, gol, nag, so4
          1. chain a [112171] picpiclink
        4. 1puu picpicxref
          complexed with cl, dox, fuc, gol, lat, nag, so4
          1. chain a [104317] picpiclink
        5. 1pum picpicxref
          complexed with cl, fuc, glb, gol, nag, so4
          1. chain a [104314] picpiclink
        6. 1oql picpicxref
          complexed with gal, nag
          1. chain a [87306] picpiclink
        7. 2r9k picpicxrefxref
          automatically matched to d1m2ta_
          complexed with cl, gol, nag, sgi, so4
          1. region a:1-248 [151789] picpiclink
        8. 1yf8 picpicxrefxref
          automatically matched to d1pc8a_
          complexed with gal, glc, man, nag, p6c
          1. region a:1-240 [123051] picpiclink
        9. 1tfm picpicxref
          complexed with bgc, bma, glb, nag, p6c
          1. chain a [106855] picpiclink
        10. 1ce7 picpicxref
          complexed with nag
          1. chain a [42194] picpiclink
        11. 2mll picpicxref
          complexed with nag
          1. chain a [42195] picpiclink
        12. 1pc8 picpicxref
          complexed with man, nag
          1. chain a [104104] picpiclink
    7. Abrin A-chain [56383]
      1. Abrus precatorius [TaxId: 3816] [56384] (1)
        1. 1abr picpicxref
          complexed with man, nag
          1. chain a [42196] picpiclink
    8. Lectin 1 A-chain [90053]
      1. Mongolian snake-gourd (Trichosanthes kirilowii) [TaxId: 3677] [90054] (1)
        1. 1ggp picpicxref
          X-ray derived abrin-based sequence
          1. chain a [83285] picpiclink
    9. Pokeweed antiviral protein alpha [56385]
      1. Pokeweed (Phytolacca americana) [TaxId: 3527] [56386] (7)
        1. 1d6a picpic
          1. chain a [42197] picpiclink
          2. chain b [42198] picpiclink
        2. 1qcg picpic
          1. chain a [42199] picpiclink
          2. chain b [42200] picpiclink
        3. 1qci picpic
          complexed with ade
          1. chain a [42201] picpiclink
          2. chain b [42202] picpiclink
        4. 1qcj picpic
          complexed with apt
          1. chain a [42203] picpiclink
          2. chain b [42204] picpiclink
        5. 1apa picpic
          1. chain a [42205] picpiclink
        6. 1paf picpic
          1. chain a [42206] picpiclink
          2. chain b [42207] picpiclink
        7. 1pag picpic
          complexed with fmp
          1. chain a [42208] picpiclink
          2. chain b [42209] picpiclink
    10. Antiviral protein 3 [90055]
      1. Pokeweed (Phytolacca americana) [TaxId: 3527] [90056] (1)
        1. 1lln picpic
          complexed with mly
          1. chain a [84625] picpiclink
    11. Antiviral protein S [103333]
      seed isoform
      1. Pokeweed (Phytolacca americana) [TaxId: 3527] [103334] (4)
        1. 1j1q picpic
          complexed with nag
          1. chain a [90768] picpiclink
        2. 1j1r picpic
          complexed with ane, nag
          1. chain a [90769] picpiclink
        3. 1j1s picpic
          complexed with fmp, nag
          1. chain a [90770] picpiclink
        4. 1gik picpic
          complexed with nag
          1. chain a [90513] picpiclink
    12. Dianthin 30 [103335]
      1. Clove pink (Dianthus caryophyllus) [TaxId: 3570] [103336] (4)
        SQ P24476 24-278
        1. 1rl0 picpic
          1. chain a [111859] picpiclink
        2. 1lp8 picpic
          1. chain a [91082] picpiclink
        3. 1lpd picpic
          complexed with ade
          1. chain a [91098] picpiclink
        4. 1lpc picpic
          complexed with cmp
          1. chain a [91097] picpiclink
    13. Saporin So6 [56387]
      1. Common soapwort (Saponaria officinalis) [TaxId: 3572] [56388] (1)
        1. 1qi7 picpic
          complexed with sul
          1. chain a [42210] picpiclink
    14. Ricin A-chain [56389]
      1. Castor bean (Ricinus communis) [TaxId: 3988] [56390] (24)
        SQ P06750 28-286
        1. 1uq5 picpic
          complexed with act, so4; mutant
          1. chain a [99778] picpiclink
        2. 1j1m picpic
          complexed with so4, tre; mutant
          1. chain a [90767] picpiclink
        3. 1uq4 picpic
          complexed with so4; mutant
          1. chain a [99777] picpiclink
        4. 2pjo picpic
          automatically matched to d1br6a_
          complexed with nmu, so4
          1. region a:6-263 [149568] picpiclink
        5. 1ift picpic
          mutant
          1. chain a [42211] picpiclink
        6. 1ifs picpic
          complexed with ane; mutant
          1. chain a [42212] picpiclink
        7. 2r3d picpic
          automatically matched to d1br6a_
          complexed with acm, so4
          1. region a:6-263 [151557] picpiclink
        8. 2p8n picpic
          automatically matched to d1br6a_
          complexed with ade, so4
          1. region a:6-263 [149313] picpiclink
        9. 1obs picpic
          mutant
          1. chain a [42213] picpiclink
        10. 1br6 picpic
          complexed with pte
          1. chain a [42214] picpiclink
        11. 1ifu picpic
          complexed with fmc; mutant
          1. chain a [42215] picpiclink
        12. 2pjn picpic
          automatically matched to d1br6a_
          complexed with so4, ure
          1. region a:6-263 [149567] picpiclink
        13. 2r2x picpic
          automatically matched to d1br6a_
          complexed with so4, ure
          1. region a:6-263 [151543] picpiclink
        14. 1obt picpic
          complexed with amp; mutant
          1. chain a [42216] picpiclink
        15. 1il4 picpic
          complexed with 9dg
          1. chain a [66200] picpiclink
        16. 1br5 picpic
          complexed with neo
          1. chain a [42217] picpiclink
        17. 1il3 picpic
          complexed with 7dg
          1. chain a [66199] picpiclink
        18. 1il5 picpic
          complexed with ddp
          1. chain a [66201] picpiclink
          2. chain b [66202] picpiclink
        19. 1rtc picpic
          1. chain a [42218] picpiclink
        20. 2aai picpicxref
          complexed with gal, glc, man, nag
          1. chain a [42219] picpiclink
        21. 1fmp picpic
          complexed with fmp
          1. chain a [42220] picpiclink
        22. 1rzo picpicxref
          complexed with glb, so4
          1. chain a [111983] picpiclink
          2. chain c [111986] picpiclink
        23. 1il9 picpic
          complexed with mog
          1. chain a [66203] picpiclink
        24. 1apg picpic
          1. chain a [42221] picpiclink
    15. Ebulin A-chain [56391]
      1. Sambucus ebulus [TaxId: 28503] [56392] (4)
        1. 1hwm picpicxref
          complexed with gal, man, nag
          1. chain a [42222] picpiclink
        2. 1hwo picpicxref
          complexed with gal, glc, man, nag
          1. chain a [42223] picpiclink
        3. 1hwn picpicxref
          complexed with gal, nag
          1. chain a [42224] picpiclink
        4. 1hwp picpicxref
          complexed with gal, glc, man, nag, pt1
          1. chain a [42225] picpiclink
    16. Bouganin [160915]
      1. Bougainvillea (Bougainvillea spectabilis) [TaxId: 146096] [160916] (1)
        SQ Q8W4U4 27-272
        1. 3ctk picpic
          1. region a:3-248 [156985] picpiclink
    17. Agglutinin-1 chain A [160917]
      1. Abrus precatorius [TaxId: 3816] [160918] (1)
        SQ Q9M6E9 22-268
        1. 2q3n picpicxrefxref
          complexed with nag
          1. region a:2-248 [150034] picpiclink
  2. Shiga toxin, A-chain [56395] (2)
    1. Shiga toxin, A-chain [56396]
      1. Shigella dysenteriae, toxin I [TaxId: 622] [56397] (2)
        1. 1r4q picpicxref
          1. chain a [97031] picpiclink
          2. chain l [97042] picpiclink
        2. 1dm0 picpicxref
          1. chain a [42227] picpiclink
          2. chain l [42228] picpiclink
      2. Shigella dysenteriae, toxin II [TaxId: 622] [103337] (2)
        1. 1r4p picpicxref
          complexed with 1ps, edo, fmt, na
          1. chain a [97025] picpiclink
        2. 2ga4 picpicxrefxrefxrefxrefxref
          automatically matched to d1r4pa_
          complexed with 1ps, ade, edo, fmt, na
          1. region a:1-297 [134854] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk