Structural Classification of Proteins
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Fold: Ribosome inactivating proteins (RIP)

contains mixed beta-sheet

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Ribosome inactivating proteins (RIP) [56370]
    contains mixed beta-sheet

Superfamilies:

  1. Ribosome inactivating proteins (RIP) [56371] (2)
    link to SUPERFAMILY database - Superfamily
    1. Plant cytotoxins [56372] (17)
      1. alpha-Trichosanthin [56373]
        1. Mongolian snake gourd (Trichosanthes kirilowii Maxim.) [TaxId: 3677] [56374] (10)
          1. 1mrj picpic
            complexed with adn
            1. chain a [42177] picpiclink
          2. 1mrk picpic
            complexed with fmc
            1. chain a [42178] picpiclink
          3. 1gis picpic
            complexed with amp; mutant
            1. chain a [83289] picpiclink
          4. 1nli picpic
            complexed with ade; mutant
            1. chain a [80625] picpiclink
          5. 1tcs picpic
            complexed with ndp
            1. chain a [42179] picpiclink
          6. 1qd2 picpic
            complexed with ade
            1. chain a [42180] picpiclink
          7. 1j4g picpic
            complexed with ca
            1. chain a [66379] picpiclink
            2. chain b [66380] picpiclink
            3. chain c [66381] picpiclink
            4. chain d [66382] picpiclink
          8. 1giu picpic
            complexed with ade; mutant
            1. chain a [83290] picpiclink
          9. 2jdl picpic
            automatically matched to d1mrja_
            1. region a:2-247 [147987] picpiclink
          10. 2jdl picpic
            automatically matched to d1mrja_
            1. region b:2-247 [147988] picpiclink
      2. Bryodin [56375]
        1. Red briony (Bryonia dioica) [TaxId: 3652] [56376] (1)
          1. 1bry picpic
            1. chain y [42181] picpiclink
            2. chain z [42182] picpiclink
      3. Beta-luffin [103331]
        1. Smooth loofah (Luffa cylindrica) [TaxId: 3670] [103332] (1)
          1. 1nio picpic
            complexed with nag
            1. chain a [91890] picpiclink
      4. alpha-Momorcharin (momordin) [56377]
        1. Bitter gourd (Momordica charantia) [TaxId: 3673] [56378] (8)
          1. 1ahc picpic
            1. chain a [42184] picpiclink
          2. 1mrg picpic
            complexed with adn
            1. chain a [42183] picpiclink
          3. 1ahb picpic
            complexed with fmp
            1. chain a [42185] picpiclink
          4. 1aha picpic
            complexed with ade
            1. chain a [42187] picpiclink
          5. 1mom picpic
            complexed with nag
            1. chain a [42188] picpiclink
          6. 1mrh picpic
            complexed with fmc
            1. chain a [42186] picpiclink
          7. 1f8q picpic
            complexed with ccn, man, nag, ptd, xys
            1. chain a [42189] picpiclink
          8. 1mri picpic
            1. chain a [42190] picpiclink
      5. Beta-momorcharin [56379]
        (almost) identical with the anti-tumor and anti-HIV-1 protein MAP30
        1. Bitter gourd (Momordica charantia) [TaxId: 3673] [56380] (2)
          1. 1cf5 picpic
            complexed with bma, fuc, man, nag, xys
            1. chain a [42191] picpiclink
            2. chain b [42192] picpiclink
          2. 1d8v picpic
            1. chain a [42193] picpiclink
      6. Mistletoe lectin I A-chain [56381]
        1. European mistletoe (Viscum album) [TaxId: 3972] [56382] (12)
          different sequence variants
          SQ P81446 1-249
          SQ Q6ITZ3 1-240
          1. 1m2t picpicxref
            complexed with ade, fuc, gol, nag
            1. chain a [84761] picpiclink
          2. 1onk picpicxref
            complexed with azi, gol, nag, po4
            1. chain a [93359] picpiclink
          3. 1sz6 picpicxref
            complexed with azi, cl, gol, nag, so4
            1. chain a [112171] picpiclink
          4. 1puu picpicxref
            complexed with cl, dox, fuc, gol, lat, nag, so4
            1. chain a [104317] picpiclink
          5. 1pum picpicxref
            complexed with cl, fuc, glb, gol, nag, so4
            1. chain a [104314] picpiclink
          6. 1oql picpicxref
            complexed with gal, nag
            1. chain a [87306] picpiclink
          7. 2r9k picpicxrefxref
            automatically matched to d1m2ta_
            complexed with cl, gol, nag, sgi, so4
            1. region a:1-248 [151789] picpiclink
          8. 1yf8 picpicxrefxref
            automatically matched to d1pc8a_
            complexed with gal, glc, man, nag, p6c
            1. region a:1-240 [123051] picpiclink
          9. 1tfm picpicxref
            complexed with bgc, bma, glb, nag, p6c
            1. chain a [106855] picpiclink
          10. 1ce7 picpicxref
            complexed with nag
            1. chain a [42194] picpiclink
          11. 2mll picpicxref
            complexed with nag
            1. chain a [42195] picpiclink
          12. 1pc8 picpicxref
            complexed with man, nag
            1. chain a [104104] picpiclink
      7. Abrin A-chain [56383]
        1. Abrus precatorius [TaxId: 3816] [56384] (1)
          1. 1abr picpicxref
            complexed with man, nag
            1. chain a [42196] picpiclink
      8. Lectin 1 A-chain [90053]
        1. Mongolian snake-gourd (Trichosanthes kirilowii) [TaxId: 3677] [90054] (1)
          1. 1ggp picpicxref
            X-ray derived abrin-based sequence
            1. chain a [83285] picpiclink
      9. Pokeweed antiviral protein alpha [56385]
        1. Pokeweed (Phytolacca americana) [TaxId: 3527] [56386] (7)
          1. 1d6a picpic
            1. chain a [42197] picpiclink
            2. chain b [42198] picpiclink
          2. 1qcg picpic
            1. chain a [42199] picpiclink
            2. chain b [42200] picpiclink
          3. 1qci picpic
            complexed with ade
            1. chain a [42201] picpiclink
            2. chain b [42202] picpiclink
          4. 1qcj picpic
            complexed with apt
            1. chain a [42203] picpiclink
            2. chain b [42204] picpiclink
          5. 1apa picpic
            1. chain a [42205] picpiclink
          6. 1paf picpic
            1. chain a [42206] picpiclink
            2. chain b [42207] picpiclink
          7. 1pag picpic
            complexed with fmp
            1. chain a [42208] picpiclink
            2. chain b [42209] picpiclink
      10. Antiviral protein 3 [90055]
        1. Pokeweed (Phytolacca americana) [TaxId: 3527] [90056] (1)
          1. 1lln picpic
            complexed with mly
            1. chain a [84625] picpiclink
      11. Antiviral protein S [103333]
        seed isoform
        1. Pokeweed (Phytolacca americana) [TaxId: 3527] [103334] (4)
          1. 1j1q picpic
            complexed with nag
            1. chain a [90768] picpiclink
          2. 1j1r picpic
            complexed with ane, nag
            1. chain a [90769] picpiclink
          3. 1j1s picpic
            complexed with fmp, nag
            1. chain a [90770] picpiclink
          4. 1gik picpic
            complexed with nag
            1. chain a [90513] picpiclink
      12. Dianthin 30 [103335]
        1. Clove pink (Dianthus caryophyllus) [TaxId: 3570] [103336] (4)
          SQ P24476 24-278
          1. 1rl0 picpic
            1. chain a [111859] picpiclink
          2. 1lp8 picpic
            1. chain a [91082] picpiclink
          3. 1lpd picpic
            complexed with ade
            1. chain a [91098] picpiclink
          4. 1lpc picpic
            complexed with cmp
            1. chain a [91097] picpiclink
      13. Saporin So6 [56387]
        1. Common soapwort (Saponaria officinalis) [TaxId: 3572] [56388] (1)
          1. 1qi7 picpic
            complexed with sul
            1. chain a [42210] picpiclink
      14. Ricin A-chain [56389]
        1. Castor bean (Ricinus communis) [TaxId: 3988] [56390] (24)
          SQ P06750 28-286
          1. 1uq5 picpic
            complexed with act, so4; mutant
            1. chain a [99778] picpiclink
          2. 1j1m picpic
            complexed with so4, tre; mutant
            1. chain a [90767] picpiclink
          3. 1uq4 picpic
            complexed with so4; mutant
            1. chain a [99777] picpiclink
          4. 2pjo picpic
            automatically matched to d1br6a_
            complexed with nmu, so4
            1. region a:6-263 [149568] picpiclink
          5. 1ift picpic
            mutant
            1. chain a [42211] picpiclink
          6. 1ifs picpic
            complexed with ane; mutant
            1. chain a [42212] picpiclink
          7. 2r3d picpic
            automatically matched to d1br6a_
            complexed with acm, so4
            1. region a:6-263 [151557] picpiclink
          8. 2p8n picpic
            automatically matched to d1br6a_
            complexed with ade, so4
            1. region a:6-263 [149313] picpiclink
          9. 1obs picpic
            mutant
            1. chain a [42213] picpiclink
          10. 1br6 picpic
            complexed with pte
            1. chain a [42214] picpiclink
          11. 1ifu picpic
            complexed with fmc; mutant
            1. chain a [42215] picpiclink
          12. 2pjn picpic
            automatically matched to d1br6a_
            complexed with so4, ure
            1. region a:6-263 [149567] picpiclink
          13. 2r2x picpic
            automatically matched to d1br6a_
            complexed with so4, ure
            1. region a:6-263 [151543] picpiclink
          14. 1obt picpic
            complexed with amp; mutant
            1. chain a [42216] picpiclink
          15. 1il4 picpic
            complexed with 9dg
            1. chain a [66200] picpiclink
          16. 1br5 picpic
            complexed with neo
            1. chain a [42217] picpiclink
          17. 1il3 picpic
            complexed with 7dg
            1. chain a [66199] picpiclink
          18. 1il5 picpic
            complexed with ddp
            1. chain a [66201] picpiclink
            2. chain b [66202] picpiclink
          19. 1rtc picpic
            1. chain a [42218] picpiclink
          20. 2aai picpicxref
            complexed with gal, glc, man, nag
            1. chain a [42219] picpiclink
          21. 1fmp picpic
            complexed with fmp
            1. chain a [42220] picpiclink
          22. 1rzo picpicxref
            complexed with glb, so4
            1. chain a [111983] picpiclink
            2. chain c [111986] picpiclink
          23. 1il9 picpic
            complexed with mog
            1. chain a [66203] picpiclink
          24. 1apg picpic
            1. chain a [42221] picpiclink
      15. Ebulin A-chain [56391]
        1. Sambucus ebulus [TaxId: 28503] [56392] (4)
          1. 1hwm picpicxref
            complexed with gal, man, nag
            1. chain a [42222] picpiclink
          2. 1hwo picpicxref
            complexed with gal, glc, man, nag
            1. chain a [42223] picpiclink
          3. 1hwn picpicxref
            complexed with gal, nag
            1. chain a [42224] picpiclink
          4. 1hwp picpicxref
            complexed with gal, glc, man, nag, pt1
            1. chain a [42225] picpiclink
      16. Bouganin [160915]
        1. Bougainvillea (Bougainvillea spectabilis) [TaxId: 146096] [160916] (1)
          SQ Q8W4U4 27-272
          1. 3ctk picpic
            1. region a:3-248 [156985] picpiclink
      17. Agglutinin-1 chain A [160917]
        1. Abrus precatorius [TaxId: 3816] [160918] (1)
          SQ Q9M6E9 22-268
          1. 2q3n picpicxrefxref
            complexed with nag
            1. region a:2-248 [150034] picpiclink
    2. Shiga toxin, A-chain [56395] (2)
      1. Shiga toxin, A-chain [56396]
        1. Shigella dysenteriae, toxin I [TaxId: 622] [56397] (2)
          1. 1r4q picpicxref
            1. chain a [97031] picpiclink
            2. chain l [97042] picpiclink
          2. 1dm0 picpicxref
            1. chain a [42227] picpiclink
            2. chain l [42228] picpiclink
        2. Shigella dysenteriae, toxin II [TaxId: 622] [103337] (2)
          1. 1r4p picpicxref
            complexed with 1ps, edo, fmt, na
            1. chain a [97025] picpiclink
          2. 2ga4 picpicxrefxrefxrefxrefxref
            automatically matched to d1r4pa_
            complexed with 1ps, ade, edo, fmt, na
            1. region a:1-297 [134854] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk