Structural Classification of Proteins

Fold: ADC synthase

: duplication: contains four repeats of alpha-beta(2)-beta motif arranged in a 4 layer core structure: alpha/beta/beta/alpha; orthogonally packed beta-sheets

Lineage:

Root: scop
Class: Alpha and beta proteins (a+b) [53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold: ADC synthase [56321]
duplication: contains four repeats of alpha-beta(2)-beta motif arranged in a 4 layer core structure: alpha/beta/beta/alpha; orthogonally packed beta-sheets

Superfamilies:

ADC synthase [56322] (1)
the active site is formed by additional structures inserted into the core structure
uperfamily
1. ADC synthase [56323] (7)
  1. Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE [56324]
    1. Archaeon Sulfolobus solfataricus [TaxId: 2287] [56325] (1)
      1. 1qdl
        
        chain a [42088]
    2. Salmonella typhimurium [TaxId: 90371] [64442] (1)
      1. 1i1q
        complexed with trp
        
        chain a [61543]
    3. Serratia marcescens [TaxId: 615] [64443] (2)
      1. 1i7q
        complexed with bez, ilg, mg, pyr
        
        chain a [61901]
        chain c [61903]
      2. 1i7s
        complexed with trp
        
        chain a [61905]
        chain c [61907]
  2. P-aminobenzoate synthase component I [69838]
    Aminodeoxychorismate synthase
    1. Escherichia coli [TaxId: 562] [69839] (2)
      1. 1k0g
        complexed with po4, trp
        
        chain a [67940]
        chain b [67941]
      2. 1k0e
        complexed with fmt, trp
        
        chain a [67938]
        chain b [67939]
  3. Menaquinone-specific isochorismate synthase MenF [143941]
    1. Escherichia coli [TaxId: 562] [143942] (4)
      SQ P38051 2-429
      1. 3bzn
        automatically matched to d2euaa1
        complexed with mg, so4
        
        region a:2-429 [155784]
      2. 3bzm
        automatically matched to d2euaa1
        complexed with cit
        
        region a:2-429 [155783]
      3. 2eua
        complexed with tar
        
        region a:2-429 [132380]
      4. 2eua
        automatically matched to 2EUA A:2-429
        complexed with tar
        
        region b:2-429 [132381]
  4. Salicylate synthetase Irp9 [143943]
    1. Yersinia enterocolitica [TaxId: 630] [143944] (4)
      SQ Q9X9I8 2-434
      1. 2fn0
        complexed with act, mg, po4
        
        region a:2-434 [133799]
      2. 2fn0
        automatically matched to 2FN0 A:2-434
        complexed with act, mg, po4
        
        region b:2-434 [133800]
      3. 2fn1
        automatically matched to 2FN0 A:2-434
        complexed with mg, pyr, sal
        
        region a:2-434 [133801]
      4. 2fn1
        automatically matched to 2FN0 A:2-434
        complexed with mg, pyr, sal
        
        region b:2-434 [133802]
  5. Salicylate synthase MbtI [143945]
    Mycobactin synthetase protein I
    1. Mycobacterium tuberculosis [TaxId: 1773] [143946] (5)
      SQ Q7D785 15-449
      1. 2g5f
        complexed with gol, imd, pyr
        
        region a:15-449 [134654]
      2. 2g5f
        automatically matched to 2G5F A:15-449
        complexed with gol, imd, pyr
        
        region b:17-449 [134655]
      3. 2g5f
        automatically matched to 2G5F A:15-449
        complexed with gol, imd, pyr
        
        region c:15-449 [134656]
      4. 2g5f
        automatically matched to 2G5F A:15-449
        complexed with gol, imd, pyr
        
        region d:15-449 [134657]
      5. 2i6y
        automatically matched to 2G5F A:15-449
        
        region a:17-449 [137098]