Structural Classification of Proteins
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Family: Protein serine/threonine phosphatase

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Metallo-dependent phosphatases [56299]
    4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication
  4. Superfamily: Metallo-dependent phosphatases [56300]
    different families of this superfamily are groupped in a single Pfam family, Pfam 00149
    link to SUPERFAMILY database - Superfamily
  5. Family: Protein serine/threonine phosphatase [56310]

Protein Domains:

  1. Protein phosphatase-1 (PP-1) [56311]
    1. Rabbit (Oryctolagus cuniculus), alpha isoform [TaxId: 9986] [56312] (1)
      1. 1fjm picpic
        complexed with acb, add, bme, cab, mn
        1. chain a [42082] picpiclink
        2. chain b [42083] picpiclink
    2. Human (Homo sapiens), beta isoform [TaxId: 9606] [64430] (5)
      SQ P36873
      1. 1jk7 picpic
        complexed with bme, mn, oka, so4
        1. chain a [63144] picpiclink
      2. 1it6 picpic
        complexed with cyu, mn
        1. chain a [71407] picpiclink
        2. chain b [71408] picpiclink
      3. 1u32 picpic
        complexed with bme, mn, oka
        1. chain a [107631] picpiclink
      4. 2bcd picpic
        automatically matched to d1jk7a_
        complexed with bme, mn, moq
        1. region a:6-298 [128281] picpiclink
      5. 2bdx picpic
        automatically matched to d1jk7a_
        complexed with dlq, mn
        1. region a:6-298 [128346] picpiclink
    3. Human (Homo sapiens), gamma isoform [TaxId: 9606] [111230] (1)
      SQ P37140 1-308
      1. 1s70 picpicxref
        complexed with mn, pge; mutant
        1. chain a [105316] picpiclink
    4. Rattus norvegicus [TaxId: 10116] [160869] (4)
      1. 2o8g picpic
        automatically matched to d1jk7a_
        complexed with mn
        1. region a:6-299 [148674] picpiclink
      2. 2o8g picpic
        automatically matched to d1jk7a_
        complexed with mn
        1. region b:6-299 [148675] picpiclink
      3. 2o8a picpic
        automatically matched to d1jk7a_
        1. region a:6-299 [148672] picpiclink
      4. 2o8a picpic
        automatically matched to d1jk7a_
        1. region b:6-299 [148673] picpiclink
  2. Protein phosphatase-2B (PP-2B, calcineurin A subunit) [56313]
    1. Cow (Bos taurus) [TaxId: 9913] [56314] (1)
      1. 1tco picpicxrefxref
        complexed with ca, fe, fk5, myr, po4, zn
        1. chain a [42084] picpiclink
    2. Human (Homo sapiens) [TaxId: 9606] [56315] (5)
      1. 1aui picpicxref
        complexed with ca, fe, zn
        1. chain a [42085] picpiclink
      2. 2p6b picpicxrefxref
        automatically matched to d1m63a_
        complexed with ca, fe, nh2, po4, zn
        1. region a:14-370 [139511] picpiclink
      3. 2p6b picpicxrefxref
        automatically matched to d1m63a_
        complexed with ca, fe, nh2, po4, zn
        1. region c:14-370 [139513] picpiclink
      4. 1m63 picpicxrefxref
        complexed with aba, bmt, ca, dal, fe, mle, mva, sar, zn
        1. chain a [78677] picpiclink
        2. chain e [78680] picpiclink
      5. 1mf8 picpicxrefxref
        complexed with aba, bmt, ca, dal, mle, mva, po4, sar
        1. chain a [79040] picpiclink
  3. lambda ser/thr protein phosphatase [64431]
    1. Bacteriophage lambda [TaxId: 10710] [64432] (1)
      1. 1g5b picpic
        complexed with hg, mn, so4
        1. chain a [60261] picpiclink
        2. chain b [60262] picpiclink
        3. chain c [60263] picpiclink
  4. Serine/threonine protein phosphatase 5, PP5 [111231]
    1. Human (Homo sapiens) [TaxId: 9606] [111232] (5)
      SQ P53041 176-499
      1. 1s95 picpic
        complexed with mn, mpd, pi
        1. chain a [105375] picpiclink
        2. chain b [105376] picpiclink
      2. 1wao picpicxrefxrefxrefxref
        automatically matched to d1s95b_
        complexed with mn
        1. region 1:176-499 [120814] picpiclink
      3. 1wao picpicxrefxrefxrefxref
        automatically matched to d1s95b_
        complexed with mn
        1. region 2:176-497 [120816] picpiclink
      4. 1wao picpicxrefxrefxrefxref
        automatically matched to d1s95b_
        complexed with mn
        1. region 3:176-499 [120818] picpiclink
      5. 1wao picpicxrefxrefxrefxref
        automatically matched to d1s95b_
        complexed with mn
        1. region 4:176-494 [120820] picpiclink
  5. Protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha [143933]
    1. Human (Homo sapiens) [TaxId: 9606] [143934] (11)
      SQ P67775 2-294
      1. 3c5w picpic
        automatically matched to 2IE4 C:6-293
        1. region c:6-293 [155952] picpiclink
      2. 2ie3 picpicxref
        complexed with acb, add, cab, mn
        1. region c:6-293 [145523] picpiclink
      3. 2ie4 picpicxref
        complexed with mn, oka
        1. region c:6-293 [145524] picpiclink
      4. 3dw8 picpicxrefxref
        automatically matched to 2IE4 C:6-293
        complexed with acb, add, cab, mn; mutant
        1. region c:6-293 [157909] picpiclink
      5. 3dw8 picpicxrefxref
        automatically matched to 2IE4 C:6-293
        complexed with acb, add, cab, mn; mutant
        1. region f:6-293 [157911] picpiclink
      6. 2npp picpicxrefxrefxrefxref
        automatically matched to 2IE4 C:6-293
        complexed with acb, add, cab, mn
        1. region c:6-293 [145692] picpiclink
      7. 2npp picpicxrefxrefxrefxref
        automatically matched to 2IE4 C:6-293
        complexed with acb, add, cab, mn
        1. region f:6-293 [145693] picpiclink
      8. 2nym picpicxrefxrefxrefxref
        automatically matched to 2NYL C:2-294
        complexed with acb, add, cab, mn
        1. region c:2-294 [138823] picpiclink
      9. 2nym picpicxrefxrefxrefxref
        automatically matched to 2NYL C:2-294
        complexed with acb, add, cab, mn
        1. region f:2-294 [138826] picpiclink
      10. 2nyl picpicxrefxrefxrefxref
        complexed with acb, add, cab, mn
        1. region c:2-294 [138817] picpiclink
      11. 2nyl picpicxrefxrefxrefxref
        automatically matched to 2NYL C:2-294
        complexed with acb, add, cab, mn
        1. region f:2-294 [138820] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk