Structural Classification of Proteins
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Superfamily: Metallo-dependent phosphatases

different families of this superfamily are groupped in a single Pfam family, Pfam 00149
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Metallo-dependent phosphatases [56299]
    4 layers: alpha/beta/beta/alpha; mixed beta sheets; contains duplication
  4. Superfamily: Metallo-dependent phosphatases [56300]
    different families of this superfamily are groupped in a single Pfam family, Pfam 00149
    link to SUPERFAMILY database - Superfamily

Families:

  1. Purple acid phosphatase-like [56301] (4)
    1. Plant purple acid phosphatase, catalytic domain [56302]
      also contain an Ig-like domain
      1. Kidney bean (Phaseolus vulgaris) [TaxId: 3885] [56303] (9) picpic
      2. Sweet potato (Ipomoea batatas) [TaxId: 4120] [118151] (1) picpic
        SQ Q9SE00 39-462
    2. Mammalian purple acid phosphatase [56304]
      1. Rat (Rattus norvegicus) [TaxId: 10116] [56305] (2) picpic
      2. Pig (Sus scrofa) [TaxId: 9823] [56306] (1) picpic
  2. DNA double-strand break repair nuclease [64427] (1)
    contains C-terminal alpha/beta subdomain
    1. Mre11 [64428]
      1. Archaeon Pyrococcus furiosus [TaxId: 2261] [64429] (3) picpic
        SQ Q8U1N9
  3. 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [56307] (3)
    1. 5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain [56308]
      1. Escherichia coli [TaxId: 562] [56309] (8) picpic
        SQ P07024 26-550
      2. Thermus thermophilus [TaxId: 274] [160867] (1) picpic
        SQ Q5SIP1 28-534
      3. Candida albicans [TaxId: 5476] [160868] (2) picpic
        SQ Q5A5Q7 16-337
  4. Protein serine/threonine phosphatase [56310] (9)
    1. Protein phosphatase-1 (PP-1) [56311]
      1. Rabbit (Oryctolagus cuniculus), alpha isoform [TaxId: 9986] [56312] (1) picpic
      2. Human (Homo sapiens), beta isoform [TaxId: 9606] [64430] (5) picpic
        SQ P36873
      3. Human (Homo sapiens), gamma isoform [TaxId: 9606] [111230] (1) picpic
        SQ P37140 1-308
      4. Rattus norvegicus [TaxId: 10116] [160869] (4) picpic
    2. Protein phosphatase-2B (PP-2B, calcineurin A subunit) [56313]
      1. Cow (Bos taurus) [TaxId: 9913] [56314] (1) picpic
      2. Human (Homo sapiens) [TaxId: 9606] [56315] (5) picpic
    3. lambda ser/thr protein phosphatase [64431]
      1. Bacteriophage lambda [TaxId: 10710] [64432] (1) picpic
    4. Serine/threonine protein phosphatase 5, PP5 [111231]
      1. Human (Homo sapiens) [TaxId: 9606] [111232] (5) picpic
        SQ P53041 176-499
    5. Protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha [143933]
      1. Human (Homo sapiens) [TaxId: 9606] [143934] (11) picpic
        SQ P67775 2-294
  5. Phosphoesterase-related [82803] (1)
    1. Hypothetical protein PF1291 [82804]
      1. Archaeon Pyrococcus furiosus [TaxId: 2261] [82805] (1) picpic
  6. TT1561-like [103320] (2)
    similar to purple acid and protein phosphatases
    1. Hypothetical protein TT1561 [103321]
      1. Thermus thermophilus [TaxId: 274] [103322] (1) picpic
    2. Uncharacterized protein Aq_1956 [160870]
      1. Aquifex aeolicus [TaxId: 63363] [160871] (1) picpic
        SQ O67769 4-260
  7. YfcE-like [111233] (6)
    1. Putative phosphodiesterase MJ0936 [111234]
      1. Methanococcus jannaschii [TaxId: 2190] [111235] (7) picpic
        SQ Q58346
    2. Phosphodiesterase yfcE [111236]
      1. Escherichia coli [TaxId: 562] [111237] (1) picpic
        SQ P76495
    3. Vacuolar protein sorting 29, VPS29 [143935]
      1. Mouse (Mus musculus) [TaxId: 10090] [143936] (5) picpic
        SQ Q9QZ88 1-182
      2. Cryptosporidium parvum [TaxId: 5807] [143937] (2) picpic
        SQ Q5CYJ7 5-197
      3. Homo sapiens [TaxId: 9606] [160872] (2) picpic
    4. Uncharacterized protein SP1879 [160873]
      1. Streptococcus pneumoniae [TaxId: 1313] [160874] (1) picpic
        SQ Q97NX4 1-173
  8. Hypothetical protein aq_1666 [118152] (1)
    1. Hypothetical protein aq_1666 [118153]
      1. Aquifex aeolicus [TaxId: 63363] [118154] (1) picpic
        SQ O67582
  9. DR1281-like [118155] (2)
    1. Putative phosphatase DR1281 [118156]
      1. Deinococcus radiodurans [TaxId: 1299] [118157] (1) picpic
        SQ Q9RUV0
    2. Hypothetical protein MPN349 [118158]
      1. Mycoplasma pneumoniae [TaxId: 2104] [118159] (1) picpic
        SQ P75429
  10. TTHA0625-like [143938] (1)
    part of Pfam 00149
    1. Hypothetical protein TTHA0625 [143939]
      1. Thermus thermophilus [TaxId: 274] [143940] (8) picpic
        SQ Q5SKL8 1-252
  11. GpdQ-like [160875] (2)
    part of Pfam 00149
    1. Rv0805 cyclic nucleotide phosphodiesterase [160876]
      1. Mycobacterium tuberculosis [TaxId: 1773] [160877] (3) picpic
        SQ O06629 10-265
    2. Glycerophosphodiesterase GpdQ [160878]
      1. Enterobacter aerogenes [TaxId: 548] [160879] (14) picpic
        SQ Q6XBH1 1-271
  12. ADPRibase-Mn-like [160880] (1)
    contains Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase (ADPRibase-Mn); part of Pfam 00149
    1. Uncharacterized C17orf48 homolog zgc:64213 [160881]
      1. Zebrafish (Danio rerio) [TaxId: 7955] [160882] (1) picpic
        SQ Q7T291 3-322
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk