Structural Classification of Proteins
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Superfamily: DNA clamp

link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: DNA clamp [55978]
    contains two helices and two beta sheets
    duplication: fold has internal pseudo two-fold symmetry
  4. Superfamily: DNA clamp [55979]
    link to SUPERFAMILY database - Superfamily

Families:

  1. DNA polymerase III, beta subunit [55980] (2)
    duplication: consists of three domains of this fold
    1. DNA polymerase III, beta subunit [55981]
      1. Escherichia coli [TaxId: 562] [55982] (30)
        SQ P00583
        1. 1ok7 picpic
          1. region a:1-122 [103992] picpiclink
          2. region a:123-244 [103993] picpiclink
          3. region a:245-366 [103994] picpiclink
          4. region b:1-122 [103995] picpiclink
          5. region b:123-244 [103996] picpiclink
          6. region b:245-366 [103997] picpiclink
        2. 3d1g picpic
          automatically matched to d1jqja1
          complexed with 322
          1. region a:1-122 [157200] picpiclink
        3. 3d1g picpic
          automatically matched to d1jqja2
          complexed with 322
          1. region a:123-244 [157201] picpiclink
        4. 3d1g picpic
          automatically matched to d1jqja3
          complexed with 322
          1. region a:245-366 [157202] picpiclink
        5. 3d1g picpic
          automatically matched to d1jqja1
          complexed with 322
          1. region b:1-122 [157203] picpiclink
        6. 3d1g picpic
          automatically matched to d1jqja2
          complexed with 322
          1. region b:123-244 [157204] picpiclink
        7. 3d1g picpic
          automatically matched to d1jqja3
          complexed with 322
          1. region b:245-366 [157205] picpiclink
        8. 1unn picpicxref
          complexed with so4
          1. region a:1-122 [99674] picpiclink
          2. region a:123-244 [99675] picpiclink
          3. region a:245-366 [99676] picpiclink
          4. region b:1-122 [99677] picpiclink
          5. region b:123-244 [99678] picpiclink
          6. region b:245-366 [99679] picpiclink
        9. 3bep picpic
          automatically matched to d1jqja1
          complexed with 5cy
          1. region a:1-122 [155190] picpiclink
        10. 3bep picpic
          automatically matched to d1jqja2
          complexed with 5cy
          1. region a:123-244 [155191] picpiclink
        11. 3bep picpic
          automatically matched to d1jqja3
          complexed with 5cy
          1. region a:245-366 [155192] picpiclink
        12. 3bep picpic
          automatically matched to d1jqja1
          complexed with 5cy
          1. region b:1-122 [155193] picpiclink
        13. 3bep picpic
          automatically matched to d1jqja2
          complexed with 5cy
          1. region b:123-244 [155194] picpiclink
        14. 3bep picpic
          automatically matched to d1jqja3
          complexed with 5cy
          1. region b:245-366 [155195] picpiclink
        15. 3d1e picpic
          automatically matched to d1jqja1
          1. region a:1-122 [157188] picpiclink
        16. 3d1e picpic
          automatically matched to d1jqja2
          1. region a:123-244 [157189] picpiclink
        17. 3d1e picpic
          automatically matched to d1jqja3
          1. region a:245-366 [157190] picpiclink
        18. 3d1e picpic
          automatically matched to d1jqja1
          1. region b:1-122 [157191] picpiclink
        19. 3d1e picpic
          automatically matched to d1jqja2
          1. region b:123-244 [157192] picpiclink
        20. 3d1e picpic
          automatically matched to d1jqja3
          1. region b:245-366 [157193] picpiclink
        21. 3d1f picpic
          automatically matched to d1jqja1
          complexed with 323, peg
          1. region a:1-122 [157194] picpiclink
        22. 3d1f picpic
          automatically matched to d1jqja2
          complexed with 323, peg
          1. region a:123-244 [157195] picpiclink
        23. 3d1f picpic
          automatically matched to d1jqja3
          complexed with 323, peg
          1. region a:245-366 [157196] picpiclink
        24. 3d1f picpic
          automatically matched to d1jqja1
          complexed with 323, peg
          1. region b:1-122 [157197] picpiclink
        25. 3d1f picpic
          automatically matched to d1jqja2
          complexed with 323, peg
          1. region b:123-244 [157198] picpiclink
        26. 3d1f picpic
          automatically matched to d1jqja3
          complexed with 323, peg
          1. region b:245-366 [157199] picpiclink
        27. 1mmi picpic
          1. region a:1-122 [91309] picpiclink
          2. region a:123-244 [91310] picpiclink
          3. region a:245-366 [91311] picpiclink
          4. region b:1-122 [91312] picpiclink
          5. region b:123-244 [91313] picpiclink
          6. region b:245-366 [91314] picpiclink
        28. 2pol picpic
          1. region a:1-122 [41356] picpiclink
          2. region a:123-244 [41357] picpiclink
          3. region a:245-366 [41358] picpiclink
          4. region b:1-122 [41359] picpiclink
          5. region b:123-244 [41360] picpiclink
          6. region b:245-366 [41361] picpiclink
        29. 1jql picpicxref
          mutant
          1. region a:1-122 [63231] picpiclink
          2. region a:123-244 [63232] picpiclink
          3. region a:245-366 [63233] picpiclink
        30. 1jqj picpicxrefxref
          mutant
          1. region a:1-122 [67091] picpiclink
          2. region a:123-244 [67092] picpiclink
          3. region a:245-366 [67093] picpiclink
          4. region b:1-122 [67094] picpiclink
          5. region b:123-244 [67095] picpiclink
          6. region b:245-366 [67096] picpiclink
      2. Thermotoga maritima [TaxId: 2336] [118108] (1)
        SQ Q9WYA0
        1. 1vpk picpic
          Structural genomics target
          1. region a:1-120 [113963] picpiclink
          2. region a:121-243 [113964] picpiclink
          3. region a:244-366 [113965] picpiclink
  2. DNA polymerase processivity factor [55983] (9)
    duplication: consists of two domains of this fold
    1. gp45 sliding clamp [55984]
      1. Bacteriophage RB69 [TaxId: 12353] [55985] (2)
        1. 1b77 picpic
          1. region a:1-110 [41362] picpiclink
          2. region a:111-228 [41363] picpiclink
          3. region b:1-110 [41364] picpiclink
          4. region b:111-228 [41365] picpiclink
          5. region c:1-110 [41366] picpiclink
          6. region c:111-228 [41367] picpiclink
        2. 1b8h picpic
          1. region a:1-110 [41368] picpiclink
          2. region a:111-228 [41369] picpiclink
          3. region b:1-110 [41370] picpiclink
          4. region b:111-228 [41371] picpiclink
          5. region c:1-110 [41372] picpiclink
          6. region c:111-228 [41373] picpiclink
      2. Bacteriophage T4 [TaxId: 10665] [55986] (1)
        1. 1czd picpic
          1. region a:1001-1110 [41374] picpiclink
          2. region a:1111-1228 [41375] picpiclink
          3. region b:2001-2110 [41376] picpiclink
          4. region b:2111-2228 [41377] picpiclink
          5. region c:3001-3110 [41378] picpiclink
          6. region c:3111-3228 [41379] picpiclink
    2. UL42 [55987]
      1. Human herpesvirus type 1 [TaxId: 10298] [55988] (1)
        1. 1dml picpic
          1. region a:29-169 [41380] picpiclink
          2. region a:170-319 [41381] picpiclink
          3. region c:29-169 [41382] picpiclink
          4. region c:170-319 [41383] picpiclink
          5. region e:28-169 [41384] picpiclink
          6. region e:170-319 [41385] picpiclink
          7. region g:28-169 [41386] picpiclink
          8. region g:170-319 [41387] picpiclink
    3. Proliferating cell nuclear antigen (PCNA) [55989]
      1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [55990] (5)
        SQ P15873
        1. 1plq picpic
          CASP1
          complexed with hg
          1. region a:1-126 [41388] picpiclink
          2. region a:127-258 [41389] picpiclink
        2. 2od8 picpic
          automatically matched to d1plq_1
          1. region a:1-126 [139024] picpiclink
        3. 2od8 picpic
          automatically matched to d1plq_2
          1. region a:127-255 [139025] picpiclink
        4. 1sxj picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
          complexed with adp, atg, mg; mutant
          1. region f:1-126 [106091] picpiclink
          2. region f:127-256 [106092] picpiclink
          3. region g:1-126 [106093] picpiclink
          4. region g:127-255 [106094] picpiclink
          5. region h:1-126 [106095] picpiclink
          6. region h:127-254 [106096] picpiclink
        5. 1plr picpic
          1. region a:1-126 [41390] picpiclink
          2. region a:127-258 [41391] picpiclink
      2. Human (Homo sapiens) [TaxId: 9606] [55991] (31)
        SQ P12004
        1. 1u7b picpic
          complexed with a target peptide
          1. region a:1-126 [113083] picpiclink
          2. region a:127-255 [113084] picpiclink
        2. 1axc picpic
          1. region a:1-126 [41392] picpiclink
          2. region a:127-255 [41393] picpiclink
          3. region c:1-126 [41394] picpiclink
          4. region c:127-255 [41395] picpiclink
          5. region e:1-126 [41396] picpiclink
          6. region e:127-255 [41397] picpiclink
        3. 1vym picpic
          automatically matched to d1axca1
          1. region a:1-126 [120542] picpiclink
        4. 1vym picpic
          automatically matched to d1axca2
          1. region a:127-255 [120543] picpiclink
        5. 1vym picpic
          automatically matched to d1axca1
          1. region b:1-126 [120544] picpiclink
        6. 1vym picpic
          automatically matched to d1axca2
          1. region b:127-255 [120545] picpiclink
        7. 1vym picpic
          automatically matched to d1axca1
          1. region c:1-126 [120546] picpiclink
        8. 1vym picpic
          automatically matched to d1axca2
          1. region c:127-255 [120547] picpiclink
        9. 1u76 picpic
          complexed with a target peptide
          1. region a:1-126 [113077] picpiclink
          2. region a:127-255 [113078] picpiclink
          3. region c:1-126 [113079] picpiclink
          4. region c:127-255 [113080] picpiclink
          5. region e:1-126 [113081] picpiclink
          6. region e:127-255 [113082] picpiclink
        10. 1vyj picpic
          automatically matched to d1axca1
          1. region a:1-126 [120530] picpiclink
        11. 1vyj picpic
          automatically matched to d1axca2
          1. region a:127-255 [120531] picpiclink
        12. 1vyj picpic
          automatically matched to d1axca1
          1. region c:1-126 [120532] picpiclink
        13. 1vyj picpic
          automatically matched to d1axca2
          1. region c:127-255 [120533] picpiclink
        14. 1vyj picpic
          automatically matched to d1axca1
          1. region e:1-126 [120534] picpiclink
        15. 1vyj picpic
          automatically matched to d1axca2
          1. region e:127-255 [120535] picpiclink
        16. 1vyj picpic
          automatically matched to d1axca1
          1. region g:1-126 [120536] picpiclink
        17. 1vyj picpic
          automatically matched to d1axca2
          1. region g:127-255 [120537] picpiclink
        18. 1vyj picpic
          automatically matched to d1axca1
          1. region i:1-126 [120538] picpiclink
        19. 1vyj picpic
          automatically matched to d1axca2
          1. region i:127-255 [120539] picpiclink
        20. 1vyj picpic
          automatically matched to d1axca1
          1. region k:1-126 [120540] picpiclink
        21. 1vyj picpic
          automatically matched to d1axca2
          1. region k:127-255 [120541] picpiclink
        22. 1ul1 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1axca1
          complexed with mg
          1. region a:1-126 [119684] picpiclink
        23. 1ul1 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1axca2
          complexed with mg
          1. region a:127-255 [119685] picpiclink
        24. 1ul1 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1axca1
          complexed with mg
          1. region b:1-126 [119686] picpiclink
        25. 1ul1 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1axca2
          complexed with mg
          1. region b:127-255 [119687] picpiclink
        26. 1ul1 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1axca1
          complexed with mg
          1. region c:1-126 [119688] picpiclink
        27. 1ul1 picpicxrefxrefxrefxrefxrefxref
          automatically matched to d1axca2
          complexed with mg
          1. region c:127-255 [119689] picpiclink
        28. 1w60 picpic
          automatically matched to d1axca1
          1. region a:1-126 [120648] picpiclink
        29. 1w60 picpic
          automatically matched to d1axca2
          1. region a:127-255 [120649] picpiclink
        30. 1w60 picpic
          automatically matched to d1axca1
          1. region b:1-126 [120650] picpiclink
        31. 1w60 picpic
          automatically matched to d1axca2
          1. region b:127-255 [120651] picpiclink
      3. Archaeon Pyrococcus furiosus [TaxId: 2261] [55992] (4)
        1. 1iz5 picpic
          mutant
          1. region a:2-120 [83834] picpiclink
          2. region a:126-246 [83835] picpiclink
          3. region b:2-120 [83836] picpiclink
          4. region b:126-246 [83837] picpiclink
        2. 1ge8 picpic
          mutant
          1. region a:2-117 [41398] picpiclink
          2. region a:126-247 [41399] picpiclink
        3. 1iz4 picpic
          mutant
          1. region a:2-120 [83832] picpiclink
          2. region a:126-247 [83833] picpiclink
        4. 1isq picpic
          complexed with ace; mutant
          1. region a:2-119 [76779] picpiclink
          2. region a:126-247 [76780] picpiclink
      4. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [103254] (3)
        1. 1rwz picpic
          1. region a:1-122 [98005] picpiclink
          2. region a:123-244 [98006] picpiclink
        2. 1rxz picpic
          complexed with a FEN-1 peptide, chain B
          1. region a:1-122 [98067] picpiclink
          2. region a:123-245 [98068] picpiclink
        3. 1rxm picpic
          complexed with a FEN-1 peptide, chain B
          1. region a:1-122 [98035] picpiclink
          2. region a:123-245 [98036] picpiclink
      5. Archaeon Sulfolobus tokodaii [TaxId: 111955] [111175] (1)
        SQ Q975N2
        1. 1ud9 picpic
          complexed with zn
          1. region a:1-119 [107768] picpiclink
          2. region a:127-245 [107769] picpiclink
          3. region b:1-119 [107770] picpiclink
          4. region b:127-245 [107771] picpiclink
          5. region c:1-119 [107772] picpiclink
          6. region c:127-245 [107773] picpiclink
          7. region d:1-119 [107774] picpiclink
          8. region d:127-245 [107775] picpiclink
    4. UL44 [111176]
      1. Human cytomegalovirus, HHV-5 [TaxId: 10359] [111177] (3)
        SQ P16790 1-290
        1. 1t6l picpic
          1. region a:10-135 [106574] picpiclink
          2. region a:136-270 [106575] picpiclink
        2. 1yyp picpic
          automatically matched to d1t6la1
          complexed with edo, so4
          1. region a:10-135 [124248] picpiclink
        3. 1yyp picpic
          automatically matched to d1t6la2
          complexed with edo, so4
          1. region a:136-270 [124249] picpiclink

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