Structural Classification of Proteins
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Fold: Homing endonuclease-like

alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Homing endonuclease-like [55603]
    alpha-beta(2)-alpha-beta(2)-alpha; 2 layers: a/b; antiparallel sheet 1243

Superfamilies:

  1. Glucose permease domain IIB [55604] (1)
    link to SUPERFAMILY database - Superfamily
    1. Glucose permease domain IIB [55605] (1)
      1. Glucose permease domain IIB [55606]
        1. Escherichia coli [TaxId: 562] [55607] (4) picpic
          there are differences in secondary structure packing between the two NMR-determined structures
  2. Homing endonucleases [55608] (2)
    link to SUPERFAMILY database - Superfamily
    1. Group I mobile intron endonuclease [55609] (5)
      contains two extra helices in the C-terminal extension
      1. DNA endonuclease I-CreI [55610]
        1. Chlamydomonas reinhardtii [TaxId: 3055] [55611] (13) picpic
          SQ P05725 2-154 ! SQ P05725
      2. DNA endonuclease I-dmoI [55612]
        duplication: contains tandem repeat of this fold
        1. Archaeon Desulfurococcus mobilis [TaxId: 2274] [55613] (2) picpic
      3. DNA endonuclease I-MsoI [90006]
        1. Monomastix sp. cl-1997 [TaxId: 141716] [90007] (1) picpic
      4. DNA endonuclease I-AniI [103141]
        duplication: contains tandem repeat of this fold
        1. Aspergillus nidulans [TaxId: 162425] [103142] (1) picpic
          synonym: Emericella nidulans
      5. DNA endonuclease I-SceI [118055]
        duplication: contains tandem repeat of this fold
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [118056] (1) picpic
          SQ P03882
    2. Intein endonuclease [55614] (2)
      duplication: contains tandem repeat of this fold
      1. VMA1-derived endonuclease (VDE) PI-SceI [55615]
        homing endonuclease with protein splicing activity
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [55616] (7) picpic
          SQ P17255 284-737
      2. PI-Pfui intein [55617]
        1. Archaeon Pyrococcus furiosus [TaxId: 2261] [55618] (1) picpic
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk