Fold: Aha1/BPI domain-like

core: [beta]-alpha-beta(5)-alpha; 2 layers: alpha/beta; antiparallel beta-sheet, meander

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a+b) [53931]
   Mainly antiparallel beta sheets (segregated alpha and beta regions)
3. Fold: Aha1/BPI domain-like [55393]
   core: [beta]-alpha-beta(5)-alpha; 2 layers: alpha/beta; antiparallel beta-sheet, meander

Superfamilies:

1. Activator of Hsp90 ATPase, Aha1 [103111] (1)
   consists of a single domain of this fold
   uperfamily
   1. Activator of Hsp90 ATPase, Aha1 [103112] (1)
      1. Activator of Hsp90 ATPase, Aha1 [103113]
         1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [103114] (2)
            1. 1usu
               complexed with a Hsp90 domain
               complexed with gol
               1. chain b [99886]
            2. 1usv
               complexed with a Hsp90 domain
               1. chain b [99888]
               2. chain d [99890]
               3. chain f [99892]
               4. chain h [99894]
2. Bactericidal permeability-increasing protein, BPI [55394] (1)
   duplication: consists of two clear structural repeats of this fold also containing an extra C-terminal beta-hairpin
   uperfamily
   1. Bactericidal permeability-increasing protein, BPI [55395] (1)
      1. Bactericidal permeability-increasing protein, BPI [55396]
         1. Human (Homo sapiens) [TaxId: 9606] [55397] (2)
            1. 1ewf
               complexed with pc2; mutant
               1. region a:1-217 [40024]
               2. region a:218-456 [40025]
            2. 1bp1
               CASP2
               complexed with pc; mutant
               1. region a:1-217 [40026]
               2. region a:218-456 [40027]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk