Structural Classification of Proteins
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Family: Lesion bypass DNA polymerase (Y-family), little finger domain

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Lesion bypass DNA polymerase (Y-family), little finger domain [100878]
    beta-alpha-beta(2)-alpha-beta; antiparallel beta-sheet: order 1423; "reversed" ferredoxin-like topology
  4. Superfamily: Lesion bypass DNA polymerase (Y-family), little finger domain [100879]
    link to SUPERFAMILY database - Superfamily
  5. Family: Lesion bypass DNA polymerase (Y-family), little finger domain [100880]

Protein Domains:

  1. DinB homolog (DBH) [100881]
    1. Archaeon Sulfolobus solfataricus, DNA polymerase IV [TaxId: 2287] [100882] (62)
      1. 1jx4 picpicxref
        complexed with adi, ca, mg
        1. region a:241-341 [90378] picpiclink
      2. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddy, mg
        1. region a:241-341 [118913] picpiclink
      3. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddy, mg
        1. region b:241-341 [118915] picpiclink
      4. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddy, mg
        1. region c:241-341 [118917] picpiclink
      5. 1s9f picpicxrefxrefxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddy, mg
        1. region d:241-341 [118919] picpiclink
      6. 2jej picpicxref
        automatically matched to d1n48a1
        complexed with bzg, ca, dgt
        1. region a:241-341 [138284] picpiclink
      7. 1rys picpicxref
        complexed with atp, ca, edo, na
        1. region a:241-341 [98111] picpiclink
        2. region b:241-341 [98113] picpiclink
      8. 2asd picpicxrefxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dcp, ddg
        1. region a:241-341 [127248] picpiclink
      9. 2asd picpicxrefxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dcp, ddg
        1. region b:1241-1341 [127250] picpiclink
      10. 2rdi picpicxref
        automatically matched to d1n48a1
        complexed with gol, peg
        1. region a:241-341 [151928] picpiclink
      11. 1s10 picpicxref
        complexed with ca, dcp
        1. region a:241-341 [98327] picpiclink
      12. 1s0o picpicxref
        complexed with ca, mg, ttp
        1. region a:241-341 [98296] picpiclink
        2. region b:241-341 [98298] picpiclink
      13. 2imw picpicxref
        automatically matched to d1n48a1
        complexed with ca, dad, edo
        1. region p:241-341 [137519] picpiclink
      14. 2agq picpicxref
        automatically matched to d1n48a1
        complexed with ca, doc, dtp, mg
        1. region a:241-341 [126735] picpiclink
      15. 2bq3 picpicxref
        automatically matched to d1n48a1
        complexed with ca, gne
        1. region a:241-341 [128959] picpiclink
      16. 2uvv picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dgt; mutant
        1. region a:241-342 [139984] picpiclink
      17. 2br0 picpicxref
        automatically matched to d1n48a1
        complexed with ca, dg3, gne
        1. region a:241-341 [128973] picpiclink
      18. 1jxl picpicxref
        complexed with bro, ca, dg3, edo, mg
        1. region a:241-341 [90380] picpiclink
      19. 1n48 picpicxref
        complexed with 3dr, atp, ca
        1. region a:241-342 [91615] picpiclink
      20. 2uvw picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dgt; mutant
        1. region a:241-342 [139986] picpiclink
      21. 2rdj picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, gol, tmp
        1. region a:241-341 [151930] picpiclink
      22. 2rdj picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, gol, tmp
        1. region b:241-341 [151932] picpiclink
      23. 2jef picpicxref
        automatically matched to d1n48a1
        complexed with bzg, ca, dgt, doc
        1. region a:241-341 [138278] picpiclink
      24. 2c28 picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dg3
        1. region a:241-341 [129660] picpiclink
      25. 2jeg picpicxref
        automatically matched to d1n48a1
        complexed with bzg, ca, dgt, doc
        1. region a:241-341 [138280] picpiclink
      26. 2ibk picpicxref
        automatically matched to d1n48a1
        complexed with bap, ca, edo, gol, pop
        1. region a:241-341 [147598] picpiclink
      27. 1ryr picpicxref
        complexed with atp, ca
        1. region a:241-341 [98109] picpiclink
      28. 2bqr picpicxref
        automatically matched to d1n48a1
        complexed with ca, dtp, gne
        1. region a:241-341 [128965] picpiclink
      29. 1s97 picpicxref
        complexed with ca, dct
        1. region a:241-341 [98742] picpiclink
        2. region b:241-341 [98744] picpiclink
        3. region c:241-341 [98746] picpiclink
        4. region d:241-341 [98748] picpiclink
      30. 2j6u picpicxref
        automatically matched to d1n48a1
        complexed with 6og, ca, dgt
        1. region a:244-344 [138093] picpiclink
      31. 1n56 picpicxref
        complexed with 3dr, atp, ca, mg
        1. region a:241-341 [91680] picpiclink
        2. region b:241-341 [91682] picpiclink
      32. 2r8i picpicxref
        automatically matched to d1n48a1
        complexed with ca, dtp, p; mutant
        1. region a:241-341 [151721] picpiclink
      33. 2bqu picpicxref
        automatically matched to d1n48a1
        complexed with ca, dad, gne
        1. region a:241-341 [128967] picpiclink
      34. 2jei picpicxref
        automatically matched to d1n48a1
        complexed with bzg, ca, dgt
        1. region a:241-341 [138282] picpiclink
      35. 1s0m picpicxref
        complexed with atp, bpa, ca, mg
        1. region a:241-341 [98290] picpiclink
        2. region b:241-341 [98292] picpiclink
      36. 2r8h picpicxref
        automatically matched to d1n48a1
        complexed with ca, dgt, p; mutant
        1. region a:241-341 [151719] picpiclink
      37. 2j6s picpicxref
        automatically matched to d1n48a1
        complexed with 6og, ca, dtp
        1. region a:241-342 [138089] picpiclink
      38. 2c22 picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dgt
        1. region a:241-341 [129655] picpiclink
      39. 2agp picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dgt, doc, mg
        1. region a:241-341 [126731] picpiclink
      40. 2agp picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dgt, doc, mg
        1. region b:241-341 [126733] picpiclink
      41. 2j6t picpicxref
        automatically matched to d1n48a1
        complexed with 6og, ca, dtp
        1. region a:241-341 [138091] picpiclink
      42. 2r8g picpicxref
        automatically matched to d1n48a1
        complexed with ca, dgt, p; mutant
        1. region a:241-341 [151717] picpiclink
      43. 2ago picpicxref
        automatically matched to d1n48a1
        complexed with ca, mg, pop
        1. region a:241-341 [126729] picpiclink
      44. 2asj picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddg
        1. region a:241-341 [127254] picpiclink
      45. 2asj picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddg
        1. region b:1241-1341 [127256] picpiclink
      46. 2c2d picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dtp
        1. region a:241-341 [129664] picpiclink
      47. 2uvu picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dgt; mutant
        1. region a:241-342 [139982] picpiclink
      48. 1s0n picpicxref
        complexed with ca, dcp
        1. region a:241-341 [98294] picpiclink
      49. 2va2 picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dct, dft
        1. region a:241-342 [152815] picpiclink
      50. 2va2 picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dct, dft
        1. region b:241-342 [152817] picpiclink
      51. 2asl picpicxrefxref
        automatically matched to d1n48a1
        complexed with 8og, ca, doc
        1. region a:241-341 [127258] picpiclink
      52. 2asl picpicxrefxref
        automatically matched to d1n48a1
        complexed with 8og, ca, doc
        1. region b:1241-1341 [127260] picpiclink
      53. 2atl picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dcp, ddg
        1. region a:241-341 [127296] picpiclink
      54. 2atl picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dcp, ddg
        1. region b:1241-1341 [127298] picpiclink
      55. 2c2r picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dct, doc
        1. region a:241-341 [129680] picpiclink
      56. 2uvr picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dgt; mutant
        1. region a:241-342 [139980] picpiclink
      57. 2va3 picpicxref
        automatically matched to d1n48a1
        complexed with ca, dft, dgt
        1. region a:241-342 [152819] picpiclink
      58. 2c2e picpicxref
        automatically matched to d1n48a1
        complexed with 8og, ca, dcp
        1. region a:241-341 [129666] picpiclink
      59. 2v9w picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dct, dft
        1. region a:241-342 [152811] picpiclink
      60. 2v9w picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, dct, dft
        1. region b:241-342 [152813] picpiclink
      61. 2au0 picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddg
        1. region a:241-341 [127318] picpiclink
      62. 2au0 picpicxrefxref
        automatically matched to d1n48a1
        complexed with ca, ddg
        1. region b:1241-1341 [127320] picpiclink
    2. Archaeon Sulfolobus solfataricus [TaxId: 2287] [100883] (2)
      1. 1k1s picpicxref
        mutant
        1. region a:240-344 [90386] picpiclink
      2. 1k1q picpicxref
        mutant
        1. region a:240-344 [90382] picpiclink
        2. region b:240-344 [90384] picpiclink
    3. Sulfolobus acidocaldarius Brock et al. 1972 (Sulfolobus acidocaldarius) [TaxId: 2285] [160394] (3)
      1. 3bq1 picpicxref
        automatically matched to d1k1qa1
        complexed with ca, dg3
        1. region a:240-344 [155493] picpiclink
      2. 3bq0 picpicxref
        automatically matched to d1k1qa1
        complexed with ca
        1. region a:240-344 [155491] picpiclink
      3. 3bq2 picpicxref
        automatically matched to d1k1qa1
        complexed with ca
        1. region a:240-344 [155495] picpiclink
  2. DNA polymerase eta [100884]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [100885] (5)
      1. 1jih picpicxref
        1. region a:390-509 [90374] picpiclink
        2. region b:390-509 [90376] picpiclink
      2. 2r8j picpicxrefxref
        automatically matched to d1jiha1
        complexed with ca, cpt, dcp
        1. region a:390-509 [151723] picpiclink
      3. 2r8j picpicxrefxref
        automatically matched to d1jiha1
        complexed with ca, cpt, dcp
        1. region b:390-509 [151725] picpiclink
      4. 2r8k picpicxrefxref
        automatically matched to d1jiha1
        complexed with 2oa, ca, cpt
        1. region a:390-509 [151727] picpiclink
      5. 2r8k picpicxrefxref
        automatically matched to d1jiha1
        complexed with 2oa, ca, cpt
        1. region b:390-509 [151729] picpiclink
  3. DNA polymerase IV [103036]
    1. Escherichia coli [TaxId: 562] [103037] (1)
      1. 1unn picpicxref
        little finger domain only complexed with DNA polymerase III beta subunit
        complexed with so4
        1. chain c [99680] picpiclink
        2. chain d [99681] picpiclink
  4. DNA polymerase iota [111015]
    1. Human (Homo sapiens) [TaxId: 9606] [111016] (8)
      SQ Q9UNA4
      1. 1zet picpicxref
        automatically matched to d1t3na1
        complexed with bru, doc, mg, ttp
        1. region a:300-414 [124997] picpiclink
      2. 2dpi picpicxref
        automatically matched to d1t3na1
        complexed with dcp, doc, eda, mg
        1. region a:300-414 [131612] picpiclink
      3. 2dpj picpicxref
        automatically matched to d1t3na1
        complexed with doc, eda, mg, ttp
        1. region a:300-414 [131614] picpiclink
      4. 2flp picpicxref
        automatically matched to d1t3na1
        complexed with doc
        1. region a:300-414 [133745] picpiclink
      5. 1t3n picpicxref
        complexed with doc, mg, ttp
        1. region a:300-414 [106363] picpiclink
        2. region b:720-834 [106365] picpiclink
      6. 2alz picpicxref
        automatically matched to d1t3na1
        complexed with dcp, doc, mg
        1. region a:300-414 [126994] picpiclink
      7. 2fln picpicxref
        automatically matched to d1t3na1
        complexed with doc
        1. region a:300-414 [133731] picpiclink
      8. 2fll picpicxref
        automatically matched to d1t3na1
        complexed with doc, mg, ttp
        1. region a:300-414 [133727] picpiclink
  5. DNA polymerase kappa [111017]
    1. Human (Homo sapiens) [TaxId: 9606] [111018] (1)
      SQ Q9UBT6 71-517
      1. 1t94 picpicxref
        1. region a:411-515 [106701] picpiclink
        2. region b:413-515 [106703] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk