Structural Classification of Proteins
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Superfamily: Folate-binding domain

some topological similarity to Formylmethanofuran:tetrahydromethanopterin formyltransferase
link to SUPERFAMILY database - Superfamily

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Folate-binding domain [103024]
    duplication: consists of two beta(2)-alpha-beta(3)-alpha subdomains swapped with the first strands
  4. Superfamily: Folate-binding domain [103025]
    some topological similarity to Formylmethanofuran:tetrahydromethanopterin formyltransferase
    link to SUPERFAMILY database - Superfamily

Families:

  1. Aminomethyltransferase folate-binding domain [103026] (5)
    1. N,N-dimethylglycine oxidase domain 3 [103027]
      1. Arthrobacter globiformis [TaxId: 1665] [103028] (3)
        1. 1pj5 picpicxrefxrefxref
          complexed with act, fad, na
          1. region a:428-742 [94745] picpiclink
        2. 1pj6 picpicxrefxrefxref
          complexed with fad, fol, na
          1. region a:428-742 [94749] picpiclink
        3. 1pj7 picpicxrefxrefxref
          complexed with fad, fon, na
          1. region a:428-742 [94753] picpiclink
    2. Hypothetical protein YgfZ, N-terminal domain [103029]
      1. Escherichia coli [TaxId: 562] [103030] (2)
        SQ P39179
        1. 1vly picpicxref
          Structural genomics target
          complexed with act, ca, cl, edo
          1. region a:3-243 [108872] picpiclink
        2. 1nrk picpicxref
          structural genomics
          complexed with so4
          1. region a:1-243 [92090] picpiclink
    3. Glycine cleavage system T protein, GcvT [111012]
      1. Thermotoga maritima [TaxId: 2336] [111013] (4)
        SQ Q9WY54
        1. 1wos picpicxref
          1. region a:1-278 [109469] picpiclink
        2. 1wor picpicxref
          complexed with red
          1. region a:1-278 [109467] picpiclink
        3. 1wop picpicxref
          complexed with fon
          1. region a:1-278 [109461] picpiclink
        4. 1woo picpicxref
          complexed with thl
          1. region a:1-278 [109459] picpiclink
      2. Escherichia coli [TaxId: 562] [111014] (1)
        SQ P27248
        1. 1vlo picpicxref
          Structural genomics target
          mutant
          1. region a:4-277 [108839] picpiclink
      3. Pyrococcus horikoshii [TaxId: 53953] [117996] (1)
        SQ O58888
        1. 1v5v picpicxref
          complexed with gol, peg
          1. region a:3-312 [113540] picpiclink
          2. region b:3-312 [113542] picpiclink
  2. TrmE formyl-THF-binding domain [117997] (1)
    dimeric biological unit; one subunit domain corresponds to one "unswapped" subdomain of the other family
    1. TrmE formyl-THF-binding domain [117998]
      1. Thermotoga maritima [TaxId: 2336] [117999] (2)
        SQ Q9WYA4
        1. 1xzp picpicxrefxref
          complexed with so4
          1. region a:1-117 [116256] picpiclink
          2. region b:1-117 [116257] picpiclink
        2. 1xzq picpicxrefxref
          complexed with fon
          1. region a:2-117 [116260] picpiclink
          2. region b:1-117 [116261] picpiclink

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MRC
site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk