Structural Classification of Proteins
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Family: EF-G/eEF-2 domains III and V

domain III structure is lacking some of the superfamily characters and is often disordered in crystals

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a+b) [53931]
    Mainly antiparallel beta sheets (segregated alpha and beta regions)
  3. Fold: Ferredoxin-like [54861]
    alpha+beta sandwich with antiparallel beta-sheet; (beta-alpha-beta)x2
  4. Superfamily: EF-G C-terminal domain-like [54980]
    link to SUPERFAMILY database - Superfamily
  5. Family: EF-G/eEF-2 domains III and V [54981]
    domain III structure is lacking some of the superfamily characters and is often disordered in crystals

Protein Domains:

  1. Elongation factor G (EF-G) [54982]
    domain III is seen in 1FNM but disordered in the most of other PDB entries
    1. Thermus thermophilus [TaxId: 274] [54983] (12)
      1. 2bv3 picpicxrefxrefxref
        automatically matched to d1fnma4
        complexed with gnp, mg; mutant
        1. region a:404-478 [129240] picpiclink
      2. 2bv3 picpicxrefxrefxref
        automatically matched to d1dar_4
        complexed with gnp, mg; mutant
        1. region a:600-688 [129241] picpiclink
      3. 2efg picpicxrefxrefxref
        complexed with gdp
        1. region a:600-689 [39301] picpiclink
      4. 2bm0 picpicxrefxrefxref
        automatically matched to d1fnma4
        complexed with gdp, mg; mutant
        1. region a:404-478 [128751] picpiclink
      5. 2bm0 picpicxrefxrefxref
        automatically matched to d1dar_4
        complexed with gdp, mg; mutant
        1. region a:600-689 [128752] picpiclink
      6. 1fnm picpicxrefxrefxref
        complexed with gdp, mg; mutant
        1. region a:404-482 [39302] picpiclink
        2. region a:600-688 [39303] picpiclink
      7. 1dar picpicxrefxrefxref
        complexed with gdp
        1. region a:600-689 [39300] picpiclink
      8. 2bm1 picpicxrefxrefxref
        automatically matched to d1fnma4
        complexed with gdp, mg; mutant
        1. region a:404-478 [128756] picpiclink
      9. 2bm1 picpicxrefxrefxref
        automatically matched to d1dar_4
        complexed with gdp, mg; mutant
        1. region a:600-688 [128757] picpiclink
      10. 1efg picpicxrefxrefxref
        complexed with gdp
        1. region a:600-689 [39305] picpiclink
      11. 1elo picpicxrefxrefxref
        1. region a:600-689 [39304] picpiclink
      12. 1ktv picpicxrefxrefxref
        1. region a:600-689 [91030] picpiclink
        2. region b:600-689 [91034] picpiclink
    2. Thermus thermophilus, EF-G-2 [TaxId: 274] [143371] (4)
      SQ Q5SI76 371-447! SQ Q5SI76 563-658
      TTHA1498
      1. 2dy1 picpicxrefxrefxref
        automatically matched to d1wdta5
        complexed with gtp, mg
        1. region a:378-454 [146610] picpiclink
      2. 2dy1 picpicxrefxrefxref
        automatically matched to d1wdta4
        complexed with gtp, mg
        1. region a:570-665 [146611] picpiclink
      3. 1wdt picpicxrefxrefxref
        complexed with gtp, mg
        1. region a:570-665 [120914] picpiclink
      4. 1wdt picpicxrefxrefxref
        complexed with gtp, mg
        1. region a:378-454 [120915] picpiclink
  2. Elongation factor 2 (eEF-2) [82677]
    1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [82678] (41)
      SQ P32324
      1. 1n0u picpicxrefxrefxref
        complexed with so1
        1. region a:482-560 [79760] picpiclink
        2. region a:726-842 [79761] picpiclink
      2. 1u2r picpicxrefxrefxref
        complexed with apr, dde, gdp, mg, so1
        1. region a:482-560 [107620] picpiclink
        2. region a:726-842 [107621] picpiclink
      3. 1n0v picpicxrefxrefxref
        1. region c:482-560 [79765] picpiclink
        2. region c:726-842 [79766] picpiclink
        3. region d:482-560 [79770] picpiclink
        4. region d:726-842 [79771] picpiclink
      4. 2npf picpicxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with gdp, mou
        1. region a:482-560 [138435] picpiclink
      5. 2npf picpicxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with gdp, mou
        1. region a:726-842 [138436] picpiclink
      6. 2npf picpicxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with gdp, mou
        1. region b:482-560 [138440] picpiclink
      7. 2npf picpicxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with gdp, mou
        1. region b:726-842 [138441] picpiclink
      8. 1zm9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde, p34
        1. region a:482-560 [125339] picpiclink
      9. 1zm9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde, p34
        1. region a:726-842 [125340] picpiclink
      10. 1zm9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde, p34
        1. region c:482-560 [125345] picpiclink
      11. 1zm9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde, p34
        1. region c:726-842 [125346] picpiclink
      12. 1zm9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde, p34
        1. region e:482-560 [125351] picpiclink
      13. 1zm9 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde, p34
        1. region e:726-842 [125352] picpiclink
      14. 1zm4 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde, tad
        1. region a:482-560 [125319] picpiclink
      15. 1zm4 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde, tad
        1. region a:726-842 [125320] picpiclink
      16. 1zm4 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde, tad
        1. region c:482-560 [125325] picpiclink
      17. 1zm4 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde, tad
        1. region c:726-842 [125326] picpiclink
      18. 1zm4 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde, tad
        1. region e:482-560 [125331] picpiclink
      19. 1zm4 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde, tad
        1. region e:726-842 [125332] picpiclink
      20. 2e1r picpicxrefxrefxref
        automatically matched to d1n0ua4
        complexed with gdp, sod
        1. region a:482-560 [131969] picpiclink
      21. 2e1r picpicxrefxrefxref
        automatically matched to d1n0ua5
        complexed with gdp, sod
        1. region a:726-842 [131970] picpiclink
      22. 1zm3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde
        1. region a:482-560 [125301] picpiclink
      23. 1zm3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde
        1. region a:726-842 [125302] picpiclink
      24. 1zm3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde
        1. region c:482-560 [125307] picpiclink
      25. 1zm3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde
        1. region c:726-842 [125308] picpiclink
      26. 1zm3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with dde
        1. region e:482-560 [125313] picpiclink
      27. 1zm3 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with dde
        1. region e:726-842 [125314] picpiclink
      28. 1zm2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with apr, dde
        1. region a:482-560 [125283] picpiclink
      29. 1zm2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with apr, dde
        1. region a:726-842 [125284] picpiclink
      30. 1zm2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with apr, dde
        1. region c:482-560 [125289] picpiclink
      31. 1zm2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with apr, dde
        1. region c:726-842 [125290] picpiclink
      32. 1zm2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua4
        complexed with apr, dde
        1. region e:482-560 [125295] picpiclink
      33. 1zm2 picpicxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxrefxref
        automatically matched to d1n0ua5
        complexed with apr, dde
        1. region e:726-842 [125296] picpiclink
      34. 2p8z picpicxrefxrefxref
        automatically matched to d1n0ua4
        complexed with apr, dde, gnp, so1
        1. region t:482-560 [139554] picpiclink
      35. 2p8z picpicxrefxrefxref
        automatically matched to d1n0ua5
        complexed with apr, dde, gnp, so1
        1. region t:730-842 [139555] picpiclink
      36. 2p8x picpicxrefxrefxref
        automatically matched to d1n0ua4
        complexed with apr, dde, gnp
        1. region t:482-560 [139544] picpiclink
      37. 2p8x picpicxrefxrefxref
        automatically matched to d1n0ua5
        complexed with apr, dde, gnp
        1. region t:730-842 [139545] picpiclink
      38. 2p8y picpicxrefxrefxref
        automatically matched to d1n0ua4
        complexed with apr, dde, gdp, so1
        1. region t:482-560 [139549] picpiclink
      39. 2p8y picpicxrefxrefxref
        automatically matched to d1n0ua5
        complexed with apr, dde, gdp, so1
        1. region t:730-842 [139550] picpiclink
      40. 2p8w picpicxrefxrefxref
        automatically matched to d1n0ua4
        complexed with gnp
        1. region t:482-560 [139539] picpiclink
      41. 2p8w picpicxrefxrefxref
        automatically matched to d1n0ua5
        complexed with gnp
        1. region t:730-842 [139540] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk