Structural Classification of Proteins

Superfamily: Microbial ribonucleases

: uperfamily

Lineage:

Root: scop
Class: Alpha and beta proteins (a+b) [53931]
Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold: Microbial ribonucleases [53932]
single helix packs against antiparallel beta-sheet
Superfamily: Microbial ribonucleases [53933]
uperfamily

Families:

Bacterial ribonucleases [81307] (5)
1. Barnase [81305]
  1. Bacillus amyloliquefaciens [TaxId: 1390] [53945] (60)
    1. 2c4b
      automatically matched to d1b3sa_
      complexed with 2pe, edo, fmt, gol, mes, so4, unx; mutant
      1. region a:3-110 [129801]
    2. 2c4b
      automatically matched to d1b3sa_
      complexed with 2pe, edo, fmt, gol, mes, so4, unx; mutant
      1. region b:3-110 [129803]
    3. 1a2p
      complexed with zn
      1. chain a [36140]
      2. chain b [36141]
      3. chain c [36142]
    4. 1b20
      complexed with zn
      1. chain a [36207]
      2. chain b [36208]
      3. chain c [36209]
    5. 1b2x
      complexed with zn
      1. chain a [36210]
      2. chain b [36211]
      3. chain c [36212]
    6. 1b2s
      complexed with sul; mutant
      1. chain a [36213]
      2. chain b [36214]
      3. chain c [36215]
    7. 1brn
      1. chain l [36143]
      2. chain m [36144]
    8. 2f56
      automatically matched to d1b27a_
      complexed with ure, zn
      1. region a:1-108 [132974]
    9. 2f56
      automatically matched to d1b27a_
      complexed with ure, zn
      1. region b:1-108 [132975]
    10. 2f56
      automatically matched to d1b27a_
      complexed with ure, zn
      1. region c:1-108 [132976]
    11. 1x1y
      automatically matched to d1b27a_
      mutant
      1. region a:3-110 [121610]
    12. 1x1y
      automatically matched to d1b27a_
      mutant
      1. region b:3-110 [121611]
    13. 1x1y
      automatically matched to d1b27a_
      mutant
      1. region c:3-110 [121612]
    14. 1bri
      mutant
      1. chain a [36145]
      2. chain b [36146]
      3. chain c [36147]
    15. 1brk
      complexed with zn; mutant
      1. chain a [36148]
      2. chain b [36149]
      3. chain c [36150]
    16. 1brh
      complexed with zn; mutant
      1. chain a [36151]
      2. chain b [36152]
      3. chain c [36153]
    17. 1b2z
      complexed with zn
      1. chain a [36216]
      2. chain b [36217]
      3. chain c [36218]
    18. 2f5m
      automatically matched to d1b27a_
      complexed with brj
      1. region a:1-108 [133001]
    19. 2f5m
      automatically matched to d1b27a_
      complexed with brj
      1. region b:1-108 [133002]
    20. 2f5m
      automatically matched to d1b27a_
      complexed with brj
      1. region c:1-108 [133003]
    21. 1bsc
      mutant
      1. chain a [36154]
      2. chain b [36155]
      3. chain c [36156]
    22. 1bnf
      mutant
      1. chain a [36166]
      2. chain b [36167]
      3. chain c [36168]
    23. 1brs
      mutant
      1. chain a [36163]
      2. chain b [36164]
      3. chain c [36165]
    24. 1brj
      complexed with zn; mutant
      1. chain a [36160]
      2. chain b [36161]
      3. chain c [36162]
    25. 1bsb
      mutant
      1. chain a [36157]
      2. chain b [36158]
      3. chain c [36159]
    26. 1bnj
      1. chain a [36172]
      2. chain b [36173]
      3. chain c [36174]
    27. 2f4y
      automatically matched to d1b27a_
      complexed with zn
      1. region a:1-108 [132960]
    28. 2f4y
      automatically matched to d1b27a_
      complexed with zn
      1. region b:1-108 [132961]
    29. 2f4y
      automatically matched to d1b27a_
      complexed with zn
      1. region c:1-108 [132962]
    30. 2f5w
      automatically matched to d1b27a_
      complexed with tou, zn
      1. region a:1-108 [133012]
    31. 2f5w
      automatically matched to d1b27a_
      complexed with tou, zn
      1. region b:1-108 [133013]
    32. 2f5w
      automatically matched to d1b27a_
      complexed with tou, zn
      1. region c:1-108 [133014]
    33. 1bng
      mutant
      1. chain a [36184]
      2. chain b [36185]
      3. chain c [36186]
    34. 1b21
      complexed with zn
      1. chain a [36219]
      2. chain b [36220]
      3. chain c [36221]
    35. 1bsa
      mutant
      1. chain a [36169]
      2. chain b [36170]
      3. chain c [36171]
    36. 1yvs
      trimeric domain swapped form
      complexed with so4
      1. chain a [36222]
    37. 1bns
      mutant
      1. chain a [36178]
      2. chain b [36179]
      3. chain c [36180]
    38. 1bne
      mutant
      1. chain a [36181]
      2. chain b [36182]
      3. chain c [36183]
    39. 1x1w
      automatically matched to d1b27a_
      mutant
      1. region a:3-110 [121604]
    40. 1x1w
      automatically matched to d1b27a_
      mutant
      1. region b:1-110 [121605]
    41. 1x1w
      automatically matched to d1b27a_
      mutant
      1. region c:2-110 [121606]
    42. 1bse
      mutant
      1. chain a [36175]
      2. chain b [36176]
      3. chain c [36177]
    43. 1bao
      complexed with zn; mutant
      1. chain a [36187]
      2. chain b [36188]
      3. chain c [36189]
    44. 1b27
      mutant
      1. chain a [36223]
      2. chain b [36224]
      3. chain c [36225]
    45. 1b2u
      mutant
      1. chain a [36226]
      2. chain b [36227]
      3. chain c [36228]
    46. 1x1x
      automatically matched to d1b27a_
      mutant
      1. region a:1-110 [121607]
    47. 1x1x
      automatically matched to d1b27a_
      mutant
      1. region b:1-110 [121608]
    48. 1x1x
      automatically matched to d1b27a_
      mutant
      1. region c:2-110 [121609]
    49. 1bni
      1. chain a [36193]
      2. chain b [36194]
      3. chain c [36195]
    50. 1brg
      complexed with zn; mutant
      1. chain a [36190]
      2. chain b [36191]
      3. chain c [36192]
    51. 1rnb
      complexed with so4
      1. chain a [36196]
    52. 1x1u
      automatically matched to d1b27a_
      mutant
      1. region a:1-110 [121598]
    53. 1x1u
      automatically matched to d1b27a_
      mutant
      1. region b:1-110 [121599]
    54. 1x1u
      automatically matched to d1b27a_
      mutant
      1. region c:2-110 [121600]
    55. 1ban
      mutant
      1. chain a [36197]
      2. chain b [36198]
      3. chain c [36199]
    56. 1bsd
      mutant
      1. chain a [36200]
      2. chain b [36201]
      3. chain c [36202]
    57. 1bgs
      mutant
      1. chain a [36203]
      2. chain b [36204]
      3. chain c [36205]
    58. 1b3s
      mutant
      1. chain a [36229]
      2. chain b [36230]
      3. chain c [36231]
    59. 1fw7
      1. chain a [83262]
    60. 1bnr
      1. chain a [36206]
2. Binase [81306]
  1. Bacillus intermedius [TaxId: 1400] [53946] (5)
    1. 1gou
      1. chain a [65429]
      2. chain b [65430]
    2. 1gov
      complexed with so4
      1. chain a [65431]
      2. chain b [65432]
    3. 1goy
      complexed with 3gp, so4
      1. chain a [65433]
      2. chain b [65434]
    4. 2rbi
      mutant
      1. chain a [36232]
      2. chain b [36233]
    5. 1buj
      1. chain a [36234]
3. RNase Sa [53935]
  1. Streptomyces aureofaciens [TaxId: 1894] [53936] (22)
    SQ P05798
    1. 1lni
      complexed with gol, so4
      1. chain a [74046]
      2. chain b [74047]
    2. 1t2h
      complexed with sul; mutant
      1. chain a [112217]
      2. chain b [112218]
    3. 1t2i
      mutant
      1. chain a [112219]
    4. 1rge
      complexed with 2gp, so4
      1. chain a [36028]
      2. chain b [36029]
    5. 1rgg
      complexed with so4
      1. chain a [36030]
      2. chain b [36031]
    6. 1i8v
      complexed with sul; mutant
      1. chain a [61985]
      2. chain b [61986]
    7. 1rgh
      complexed with so4
      1. chain a [36032]
      2. chain b [36033]
    8. 1rgf
      complexed with so4
      1. chain a [36034]
      2. chain b [36035]
    9. 1i70
      complexed with sul; mutant
      1. chain a [61862]
      2. chain b [61863]
    10. 1gmp
      complexed with 2gp, so4
      1. chain a [36036]
      2. chain b [36037]
    11. 1box
      mutant
      1. chain a [36038]
    12. 1ay7
      1. chain a [36041]
    13. 1gmq
      complexed with so4
      1. chain a [36039]
      2. chain b [36040]
    14. 1uci
      complexed with so4; mutant
      1. chain a [99175]
      2. chain b [99176]
    15. 1gmr
      complexed with 2gp, so4
      1. chain a [36042]
      2. chain b [36043]
    16. 1uck
      complexed with so4; mutant
      1. chain a [99179]
      2. chain b [99180]
    17. 1rsn
      complexed with sgp, so4
      1. chain a [36046]
      2. chain b [36047]
    18. 1ucl
      complexed with so4; mutant
      1. chain a [99181]
      2. chain b [99182]
    19. 1ucj
      complexed with so4; mutant
      1. chain a [99177]
      2. chain b [99178]
    20. 2sar
      complexed with gmp, so4
      1. chain a [36044]
      2. chain b [36045]
    21. 1sar
      complexed with so4
      1. chain a [36048]
      2. chain b [36049]
    22. 1c54
      1. chain a [64764]
4. Cytotoxic RNase Sa3 [82563]
  1. Streptomyces aureofaciens [TaxId: 1894] [82564] (2)
    1. 1mgr
      complexed with sul
      1. chain a [79106]
    2. 1mgw
      complexed with li
      1. chain a [79109]
5. Ribonuclease Sa2 [110767]
  1. Streptomyces aureofaciens [TaxId: 1894] [110768] (2)
    SQ Q53752
    1. 1pyl
      complexed with so4
      1. chain a [104391]
      2. chain b [104392]
    2. 1py3
      complexed with so4
      1. chain a [104386]
      2. chain b [104387]
      3. chain c [104388]
Fungal ribonucleases [81311] (5)
1. RNase F1 [53937]
  1. Fusarium moniliforme [TaxId: 117187] [53938] (4)
    1. 1fus
      1. chain a [36050]
    2. 1fut
      complexed with 2gp
      1. chain a [36051]
    3. 1rcl
      1. chain a [36052]
    4. 1rck
      1. chain a [36053]
2. RNase T1 [53939]
  1. Aspergillus oryzae [TaxId: 5062] [53940] (64)
    1. 1i0v
      complexed with 2gp, ca; mutant
      1. chain a [36054]
    2. 9rnt
      complexed with ca
      1. chain a [36055]
    3. 1lov
      complexed with 3gp, ca; mutant
      1. chain a [74166]
    4. 1loy
      complexed with 3gp, ca; mutant
      1. chain a [74168]
    5. 4gsp
      complexed with 3gp, ca, sgp
      1. chain a [36057]
    6. 1rga
      complexed with ca, gmp
      1. chain a [36056]
    7. 1i0x
      complexed with 2gp, ca; mutant
      1. chain a [36059]
      2. chain b [36060]
      3. chain c [36061]
      4. chain d [36062]
    8. 8rnt
      complexed with zn
      1. chain a [36058]
    9. 2gsp
      complexed with 3gp, ca, sgp
      1. chain a [36064]
    10. 1i3i
      complexed with 2gp, ca; mutant
      1. chain a [61593]
    11. 1q9e
      complexed with tmn; mutant
      1. chain a [96269]
      2. chain b [96270]
      3. chain c [96271]
    12. 1hyf
      complexed with 2gp, sr; mutant
      1. chain a [36065]
    13. 1rgk
      complexed with 2am, ca; mutant
      1. chain a [36067]
    14. 4bir
      complexed with ca; mutant
      1. chain a [36068]
    15. 5gsp
      complexed with 3gp, ca
      1. chain a [36072]
    16. 3gsp
      complexed with 3gp, ca, sgp
      1. chain a [36075]
    17. 1rn1
      complexed with so4
      1. chain a [36122]
      2. chain b [36123]
      3. chain c [36124]
    18. 1fzu
      complexed with 2gp, ca; mutant
      1. chain a [36071]
    19. 2rnt
      complexed with ca, gpg
      1. chain a [36063]
    20. 2aae
      complexed with ca, po4; mutant
      1. chain a [36066]
    21. 5bu4
      complexed with 2gp, ca
      1. chain a [36074]
    22. 1i2g
      complexed with 2gp, ca; mutant
      1. chain a [61567]
    23. 2hoh
      complexed with 2gp, ca, na, po4; mutant
      1. chain a [36077]
      2. chain b [36078]
      3. chain c [36079]
      4. chain d [36080]
    24. 1rhl
      complexed with 2gp, ca; mutant
      1. chain a [36082]
    25. 3rnt
      complexed with ca, vo4
      1. chain a [36069]
    26. 1rn4
      complexed with ca; mutant
      1. chain a [36073]
    27. 6rnt
      complexed with 2am, ca
      1. chain a [36070]
    28. 1i2e
      complexed with 2gp, ca; mutant
      1. chain a [61565]
    29. 4bu4
      complexed with 2gp, ca
      1. chain a [36081]
    30. 1bvi
      complexed with 2gp, ca
      1. chain a [36090]
      2. chain b [36091]
      3. chain c [36092]
      4. chain d [36093]
    31. 3hoh
      complexed with 2gp, ca; mutant
      1. chain a [36085]
      2. chain b [36086]
      3. chain c [36087]
      4. chain d [36088]
    32. 1g02
      complexed with 2gp, ca; mutant
      1. chain a [36076]
    33. 1bu4
      complexed with 2gp, ca
      1. chain a [36100]
    34. 5hoh
      complexed with 2gp, ca; mutant
      1. chain a [36096]
      2. chain b [36097]
      3. chain c [36098]
      4. chain d [36099]
    35. 3bu4
      complexed with 2gp, ca
      1. chain a [36089]
    36. 1rgl
      complexed with 2gp, ca; mutant
      1. chain a [36094]
    37. 7rnt
      complexed with 2am, ca; mutant
      1. chain a [36105]
    38. 1bir
      complexed with 2gp, ca; mutant
      1. chain a [36083]
      2. chain b [36084]
    39. 1i2f
      complexed with 2gp, ca; mutant
      1. chain a [61566]
    40. 1low
      complexed with 3gp, ca; mutant
      1. chain a [74167]
    41. 1rls
      complexed with 3gp, ca
      1. chain a [36095]
    42. 1lra
      complexed with 2gp, na; mutant
      1. chain a [36112]
    43. 1fys
      complexed with 2gp, ca; mutant
      1. chain a [36104]
    44. 2bu4
      complexed with 2gp, ca
      1. chain a [36114]
    45. 4hoh
      complexed with 2gp, ca; mutant
      1. chain a [36118]
      2. chain b [36119]
      3. chain c [36120]
      4. chain d [36121]
    46. 3bir
      complexed with 2gp, ca; mutant
      1. chain a [36132]
    47. 1rgc
      complexed with 3gp, ca; mutant
      1. chain a [36102]
      2. chain b [36103]
    48. 7gsp
      complexed with po4, sgp
      1. chain a [36108]
      2. chain b [36109]
    49. 1gsp
      complexed with ca, sgp
      1. chain a [36117]
    50. 2aad
      complexed with 2gp, ca; mutant
      1. chain a [36110]
      2. chain b [36111]
    51. 1det
      complexed with 2gp, cbm, na
      1. chain a [36101]
    52. 1b2m
      complexed with ch2; mutant
      1. chain a [36115]
      2. chain b [36116]
    53. 5bir
      complexed with 2gp, ca; mutant
      1. chain a [36106]
      2. chain b [36107]
    54. 6gsp
      complexed with 3gp, ca
      1. chain a [36125]
    55. 1rnt
      complexed with 2gp
      1. chain a [36113]
    56. 1ch0
      1. chain a [36129]
      2. chain b [36130]
      3. chain c [36131]
    57. 1i3f
      complexed with 2gp, ca; mutant
      1. chain a [61591]
    58. 4rnt
      mutant
      1. chain a [36126]
    59. 1trq
      complexed with 2gp, ca; mutant
      1. chain a [36127]
      2. chain b [36128]
    60. 2bir
      complexed with 2gp, ca
      1. chain a [36133]
    61. 1trp
      complexed with 2gp, ca; mutant
      1. chain a [36134]
      2. chain b [36135]
    62. 5rnt
      complexed with pgp
      1. chain a [36136]
    63. 1ygw
      mutant
      1. chain a [36137]
    64. 1iyy
      mutant
      1. chain a [90724]
  2. Aspergillus niger [TaxId: 5061] [53941] (1)
    1. 1hz1
      complexed with 2gp, mg; mutant
      1. chain a [36138]
3. RNase U2 [53942]
  1. Ustilago sphaerogena [TaxId: 5271] [53943] (1)
    1. 1rtu
      complexed with ias, so4
      1. chain a [36139]
4. RNase Ms [53947]
  1. Molsin (Aspergillus saitoi) [TaxId: 5063] [53948] (2)
    1. 1rds
      complexed with gpc
      1. chain a [36236]
    2. 1rms
      complexed with 3gp
      1. chain a [36235]
Ribotoxin [81310] (2)
the fungal cytotoxic ribonucleases with many insertions in the common fold
1. Restrictocin [81308]
  1. Fungus (Aspergillus restrictus) [TaxId: 5064] [53952] (4)
    1. 1jbs
      complexed with ch3, k
      1. chain a [66486]
      2. chain b [66487]
    2. 1aqz
      complexed with po4
      1. chain a [36238]
      2. chain b [36239]
    3. 1jbr
      complexed with a23, k
      1. chain a [66484]
      2. chain b [66485]
    4. 1jbt
      complexed with k
      1. chain a [66488]
      2. chain b [66489]
2. alpha-Sarcin [81309]
  1. Fungus (Aspergillus giganteus) [TaxId: 5060] [53953] (2)
    1. 1de3
      1. chain a [36240]
    2. 1r4y
      delta(7-22) mutant
      1. chain a [97056]