Structural Classification of Proteins
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Fold: Macro domain-like

3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest

Lineage:

  1. Root: scop
  2. Class: Alpha and beta proteins (a/b) [51349]
    Mainly parallel beta sheets (beta-alpha-beta units)
  3. Fold: Macro domain-like [52948]
    3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest

Superfamilies:

  1. Macro domain-like [52949] (2)
    link to SUPERFAMILY database - Superfamily
    1. Leucine aminopeptidase (Aminopeptidase A), N-terminal domain [52950] (2)
      1. Leucine aminopeptidase (Aminopeptidase A), N-terminal domain [52951]
        1. Cow (Bos taurus) [TaxId: 9913] [52952] (9)
          1. 1lam picpicxref
            complexed with co3, mpd, zn
            1. region a:1-159 [33166] picpiclink
          2. 1lcp picpicxref
            complexed with mpd, plu, zn
            1. region a:1-159 [33167] picpiclink
            2. region b:1-159 [33168] picpiclink
          3. 2j9a picpicxref
            automatically matched to d1blle1
            complexed with ahy, cl, dms, mpd, zn
            1. region a:1-159 [138150] picpiclink
          4. 2ewb picpicxref
            automatically matched to d1blle1
            complexed with co3, mpd, na, zed, zn
            1. region a:1-159 [132453] picpiclink
          5. 1lan picpicxref
            complexed with mpd, zn
            1. region a:1-159 [33169] picpiclink
          6. 1bll picpicxref
            complexed with zn
            1. region e:1-159 [33170] picpiclink
          7. 1lap picpicxref
            complexed with zn
            1. region a:1-159 [33171] picpiclink
          8. 1bpn picpicxref
            complexed with zn
            1. region a:1-159 [33173] picpiclink
          9. 1bpm picpicxref
            complexed with mg, zn
            1. region a:1-159 [33172] picpiclink
        2. Escherichia coli, PepA [TaxId: 562] [75241] (1)
          involved in Xer site-specific recombination; probable DNA-binding domain
          1. 1gyt picpicxref
            complexed with cl, co3, zn
            1. region a:1-178 [70765] picpiclink
            2. region b:1-178 [70767] picpiclink
            3. region c:1-178 [70769] picpiclink
            4. region d:1-178 [70771] picpiclink
            5. region e:1-178 [70773] picpiclink
            6. region f:1-178 [70775] picpiclink
            7. region g:1-178 [70777] picpiclink
            8. region h:1-178 [70779] picpiclink
            9. region i:1-178 [70781] picpiclink
            10. region j:1-178 [70783] picpiclink
            11. region k:1-178 [70785] picpiclink
            12. region l:1-178 [70787] picpiclink
    2. Macro domain [89724] (7)
      found in different proteins, including macro-H2a histone and the Appr-1"-p processing enzyme
      1. Hypothetical protein AF1521 [89725]
        contains extra N-terminal strand
        1. Archaeon Archaeoglobus fulgidus [TaxId: 2234] [89726] (4)
          SQ O28751
          1. 1vhu picpic
            structural genomics
            complexed with mes
            1. chain a [100703] picpiclink
          2. 2bfq picpic
            automatically matched to d1hjza_
            complexed with apr
            1. region a:1-192 [128452] picpiclink
          3. 1hjz picpic
            complexed with mes
            1. chain a [83520] picpiclink
            2. chain b [83521] picpiclink
          4. 2bfr picpic
            complexed with adp, mg
            1. chain a [116719] picpiclink
      2. Hypothetical protein YmbD [102530]
        1. Escherichia coli [TaxId: 562] [102531] (1)
          1. 1spv picpic
            structural genomics; NESG target ER58
            complexed with mes
            1. chain a [98957] picpiclink
      3. Hypothetical protein Ymr087W [110654]
        contains structural variations at both termini
        1. Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932] [110655] (3)
          SQ Q04299
          1. 1njr picpic
            complexed with xyl
            1. chain a [103858] picpiclink
          2. 1ty8 picpic
            complexed with adp, cl, na
            1. chain a [112826] picpiclink
          3. 1txz picpic
            complexed with apr, egl, na, so4
            1. chain a [112793] picpiclink
      4. Hypothetical protein BT1257 [142545]
        1. Bacteroides thetaiotaomicron [TaxId: 818] [142546] (3)
          SQ Q8A8B0 2-155
          1. 2fg1 picpic
            automatically matched to 2AFC A:2-155
            1. region a:2-155 [133400] picpiclink
          2. 2afc picpic
            1. region a:2-155 [126676] picpiclink
          3. 2afc picpic
            automatically matched to 2AFC A:2-155
            1. region b:2-155 [126677] picpiclink
      5. Histone macro-H2a1.1 [142547]
        1. Rat (Rattus norvegicus) [TaxId: 10116] [142548] (4)
          SQ Q02874 180-370
          1. 1yd9 picpic
            Isoform 1
            complexed with au
            1. region a:6-193 [122976] picpiclink
          2. 1yd9 picpic
            automatically matched to 1YD9 A:6-193
            complexed with au
            1. region b:6-192 [122977] picpiclink
          3. 1yd9 picpic
            automatically matched to 1YD9 A:6-193
            complexed with au
            1. region c:6-191 [122978] picpiclink
          4. 1yd9 picpic
            automatically matched to 1YD9 A:6-193
            complexed with au
            1. region d:6-193 [122979] picpiclink
        2. Human (Homo sapiens) [TaxId: 9606] [142549] (8)
          SQ O75367 179-367! SQ O75367 181-371
          1. 1zr3 picpic
            automatically matched to 2FXK A:182-368
            complexed with mes
            1. region a:182-367 [125513] picpiclink
          2. 1zr3 picpic
            automatically matched to 2FXK A:182-368
            complexed with mes
            1. region b:182-367 [125514] picpiclink
          3. 1zr3 picpic
            automatically matched to 2FXK A:182-368
            complexed with mes
            1. region c:183-366 [125515] picpiclink
          4. 1zr3 picpic
            automatically matched to 2FXK A:182-368
            complexed with mes
            1. region d:183-366 [125516] picpiclink
          5. 2fxk picpic
            isoform 1
            mutant
            1. region a:182-368 [134323] picpiclink
          6. 2fxk picpic
            automatically matched to 2FXK A:182-368
            mutant
            1. region b:182-368 [134324] picpiclink
          7. 1zr5 picpic
            1. region a:179-367 [125525] picpiclink
          8. 1zr5 picpic
            automatically matched to 1ZR5 A:179-367
            1. region b:181-367 [125526] picpiclink
      6. Replicase polyprotein 1ab [142550]
        1. SARS coronavirus [TaxId: 227859] [142551] (4)
          SQ P59641 1002-1169
          1. 2acf picpic
            complexed with gol
            1. region a:184-351 [126547] picpiclink
          2. 2acf picpic
            automatically matched to 2ACF A:184-351
            complexed with gol
            1. region b:184-351 [126548] picpiclink
          3. 2acf picpic
            automatically matched to 2ACF A:184-351
            complexed with gol
            1. region c:184-351 [126549] picpiclink
          4. 2acf picpic
            automatically matched to 2ACF A:184-351
            complexed with gol
            1. region d:184-351 [126550] picpiclink
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MRC site Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009
Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk