Fold: CobE/GbiG C-terminal domain-like

3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32154; strand 5 is antiparallel to the rest

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: CobE/GbiG C-terminal domain-like [159663]
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32154; strand 5 is antiparallel to the rest

Superfamilies:

1. CobE/GbiG C-terminal domain-like [159664] (1)
   probably involved in deacylation steps in both anaerobic and aerobic pathways of cobalamin biosynthesis
   1. CobE/GbiG C-terminal domain-like [159665] (3)
      C-terminal part of Pfam 01890 (CbiG); corresponds to standalone protein CobE in the aerobic pathway; also includes resent structure 3BY5
      1. Cobalamin biosynthesis protein CobE [159666]
         predicted to facilitate the deacylation of precorrin-5 intermediate; this step can proceed non-enzymatically in vitro
         1. Agrobacterium tumefaciens [TaxId: 358] [159667] (1)
            SQ A9CHC6 8-130
            CobE orthologue Atu2797/ChiG; typo in the (mis)annotation
            1. 3by5
               complexed with so4
               1. region a:8-130 [155721]
         2. Pseudomonas aeruginosa [TaxId: 287] [159668] (1)
            SQ Q9HZQ0 1-139
            1. 2w6k
               previously 2BSN
               complexed with gol, so4
               1. region a:1-139 [153740]
      2. Cobalamin biosynthesis protein G, CbiG [159669]
         1. Sulfolobus solfataricus [TaxId: 2287] [159670] (2)
            SQ Q97WD0 215-335
            1. 3eeq
               complexed with so4
               1. region a:215-335 [158123]
            2. 3eeq
               automatically matched to 3EEQ A:215-335
               complexed with so4
               1. region b:215-335 [158125]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk