Family: DsbA-like

contains an all-alpha subdomain insertion

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: Thioredoxin fold [52832]
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
4. Superfamily: Thioredoxin-like [52833]
   uperfamily
5. Family: DsbA-like [100953]
   contains an all-alpha subdomain insertion

Protein Domains:

1. Disulfide-bond formation facilitator (DsbA) [100954]
   the insert subdomain is a 4-helical bundle
   1. Escherichia coli [TaxId: 562] [100955] (22)
      1. 1fvk
         1. chain a [90351]
         2. chain b [90352]
      2. 1ac1
         mutant
         1. chain a [90326]
         2. chain b [90327]
      3. 1acv
         mutant
         1. chain a [90328]
         2. chain b [90329]
      4. 1a2j
         1. chain a [90321]
      5. 1dsb
         1. chain a [90347]
         2. chain b [90348]
      6. 2b3s
         automatically matched to d1ac1a_
         mutant
         1. region a:2-188 [127794]
      7. 2b3s
         automatically matched to d1ac1a_
         mutant
         1. region b:2-188 [127795]
      8. 1fvj
         mutant
         1. chain a [90349]
         2. chain b [90350]
      9. 1u3a
         automatically matched to d1a23__
         complexed with pe5; mutant
         1. region a:3-188 [119504]
      10. 1u3a
          automatically matched to d1a23__
          complexed with pe5; mutant
          1. region b:3-188 [119505]
      11. 1u3a
          automatically matched to d1a23__
          complexed with pe5; mutant
          1. region d:3-188 [119506]
      12. 1u3a
          automatically matched to d1a23__
          complexed with pe5; mutant
          1. region e:3-188 [119507]
      13. 1a2l
          1. chain a [90322]
          2. chain b [90323]
      14. 1bq7
          mutant
          1. chain a [90331]
          2. chain b [90332]
          3. chain c [90333]
          4. chain d [90334]
          5. chain e [90335]
          6. chain f [90336]
      15. 1a2m
          1. chain a [90324]
          2. chain b [90325]
      16. 1ti1
          automatically matched to d1a23__
          complexed with d12; mutant
          1. region a:3-188 [119278]
      17. 2b6m
          automatically matched to d1ac1a_
          complexed with peg; mutant
          1. region a:2-188 [127995]
      18. 2b6m
          automatically matched to d1ac1a_
          complexed with peg; mutant
          1. region b:2-188 [127996]
      19. 1a24
          1. chain a [90320]
      20. 1a23
          1. chain a [90319]
      21. 2hi7
          automatically matched to d1a23__
          complexed with uq1, zn; mutant
          1. region a:1-188 [136524]
      22. 1un2
          circularly permuted cpdsba_q100t99
          1. chain a [99645]
   2. Vibrio cholerae [TaxId: 666] [100956] (1)
      TcpG, periplasmic enzyme required for the maturation of secreted virulence factors
      1. 1bed
         1. chain a [90330]
2. Mitochondrial class kappa glutathione S-transferase [102437]
   contains larger and less compact insertion in the common fold than DsbA
   1. Rat (Rattus norvegicus) [TaxId: 10116] [102438] (1)
      1. 1r4w
         complexed with gsh
         1. chain a [97050]
         2. chain b [97051]
         3. chain c [97052]
         4. chain d [97053]
3. Hypothetical protein EF0770 [142359]
   1. Enterococcus faecalis [TaxId: 1351] [142360] (1)
      SQ Q837R1 1-172
      1. 1z6m
         complexed with po4
         1. region a:1-172 [124529]

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk