Family: Dual specificity phosphatase-like

Lineage:

1. Root: scop
2. Class: Alpha and beta proteins (a/b) [51349]
   Mainly parallel beta sheets (beta-alpha-beta units)
3. Fold: (Phosphotyrosine protein) phosphatases II [52798]
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
4. Superfamily: (Phosphotyrosine protein) phosphatases II [52799]
   share with the family I the common active site structure with a circularly permuted topology
   uperfamily
5. Family: Dual specificity phosphatase-like [52800]

Protein Domains:

1. VH1-related dual-specificity phosphatase, VHR [52801]
   1. Human (Homo sapiens) [TaxId: 9606] [52802] (2)
2. Mapk phosphatase [52803]
   1. Human (Homo sapiens), pyst1 (mkp3) [TaxId: 9606] [52804] (1)
   2. Human (Homo sapiens), pac-1 [TaxId: 9606] [75232] (1)
3. Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain [52818]
   1. Human (Homo sapiens) [TaxId: 9606] [52819] (1)
4. Proline directed phosphatase CDC14b2 [89698]
   duplication: consists of two structurally similar domains with the catalytic site being in the C-terminal domain
   1. Human (Homo sapiens) [TaxId: 9606] [89699] (3)
5. Protein tyrosine phosphatase type IVa [102418]
   1. Human (Homo sapiens), pr-3 [TaxId: 9606] [102419] (2)
      SQ O75365 1-162 # 99% sequence identity
   2. Human (Homo sapiens), pr-1 [TaxId: 9606] [117578] (1)
      SQ Q93096 9-160
6. mRNA capping enzyme, triphosphatase domain [64047]
   1. Mouse (Mus musculus) [TaxId: 10090] [64048] (2)
7. Kinase associated phosphatase (kap) [64049]
   1. Human (Homo sapiens) [TaxId: 9606] [64050] (2)
8. Putative phosphatase At1g05000 [117579]
   1. Thale cress (Arabidopsis thaliana) [TaxId: 3702] [117580] (3)
      SQ Q9ZVN4 52-201

Generated from scop database 1.75 with scopm 1.101 on Wed Jun 3 10:42:06 2009 Copyright © 1994-2009 The scop authors / scop@mrc-lmb.cam.ac.uk